The size of the grow has nothing at all to do with it. It's time that I am talking about. Time becomes the enemy when things are not maintained at optimum levels.
My experience has been that over time if I allow and encourage the ongoing life of the soil (microbially) is that the pH stabalizes to that conducive to the plant life growing in the soil. That is as long as I don't do something silly like try out some crazy fertilizer or something. I do realize that not everyone can do this. (generally in soil, bacteria create a higher pH and fungi a lower so in a balanced ratio with input from the plants given sufficient organic matter the pH should balance to the appropriate level)