acespicoli
Well-known member
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Disease | Active compound | Receptors | Mechanism of Action |
---|---|---|---|
Parkinson’s | THC, CBD | Non-Cannabinoid receptors | Antioxidant activity |
CB2 | Decreases proinflammatory cytokines and NFkb pathway activity | ||
THCV | CB2 | Decreases proinflammatory cytokines & ROS. Increases anti-inflammatory cytokines | |
Huntington Disease | THC, CBD | Non-Cannabinoid receptors | Decreases oxidative stress and edema |
THC | CB1 | Neuroprotective activity | |
CBG | Cannabinoid & Non-cannabinoid receptors | Reduces mutant Htt protein aggregation. Counteract superregulation of proinflammatory markers | |
Alzheimer’s disease | THC | CB1 | Inhibits AChE neurotransmitter |
CBD | CB2 | Inhibits amyloid-β plaque formation. Modulates iNOS expression | |
CBD | PPAR-y | Decreases amyloid-β production and reduces apoptosis | |
Multiple Sclerosis | THC | CB1 | Reduces neuroinflammation. Prevents excitotoxicity by reducing glutamate release |
Amyotrophic Lateral Sclerosis | THC | CB2 | Reduces excitotoxicity by reducing glutamate release. Reduces oxidative cell damage. |
Hypoxia-Ischemia | CBD | CB2, 5HT1A | Modulation of oxidative stress and inflammation. Modulation of glutamate and cytokine release. Modulation of COX-3 induction |
Epilepsy | CBD | GPR55, TPRV-1, 5HT1A | Reduction of Ca2+ in synaptic complex of neurons |
THC | CB1 | Modulates GABA release | |
Pain | THC, CBD | CB1, CB2 | Inhibits the release of neurotransmitters from presynaptic nerve. Activates the descending inhibitory pain pathways. |
CBD | TRPV-1 | Desensitizes TRPV-1 receptor and inhibits activation of other intermediary molecules of signaling pathway. | |
Apptetite | THC, CBD | CB1, CB2 | Upregulates ghrelin and downregulates leptin hormone |
Respiratory Disorder | THC | CB1, CB2 | Prevents fibrosis in lung, liver, heart, kidney, and skin cells. Reduces inflammation, oxidative/nitrosative stress. |
Going to start with this rate to make cannabis capsules. Need to work up to a comfortable dose using this variety.1 gram decarbed Hash
5 ml coconut oil (1 teaspoon)
2ml lecithin (1/4 teaspoon)
Heat 220 F for 10 minutes
Freeze
Reheat.
Fills about 10 capsules. Same general strength as the 5 gram version.
What is the general THC content of kief per gram?
This is something I intend to persue in earnest with cbd rich ... well also balanced thc/cbd strains to use as feed material for these medications. Also the potency and tolerance needs to be monitored closely.![]()
RSO FECO Liposomal Encapsulation | badkittysmiles
www.badkatscannapharm.com
Lots of great methods of making concentrates on here and also a number of great cannabis infused recipes.
THE CARBON COPY OF THE SITE IS HERE FOR REFERENCE![]()
RSO FECO Liposomal Encapsulation | badkittysmiles
www.badkatscannapharm.com
Lots of great methods of making concentrates on here and also a number of great cannabis infused recipes.