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The Original O'l Farts Club.

OleReynard

Well-known member
I did a lot of reading up and a lot of YouTube watching so I could learn the basics. I knew nothing about them except always wanting to try them before I started. What kind of shrooms did you want to grow?
Don't even know that yet something I've never ventured into.
I hear of shroom bars from out west, might have to get a handle on those.
Buddy in Ill buys them by the case.
 

Unca Walt

Well-known member
420club
Jeebus! Lookit:
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Unca Walt

Well-known member
420club
I’m not sure how they compare to other shrooms walt They are the only ones I’ve tried so far. I know there are stronger ones. These so far are great for me but maybe I’m now brave enough to try some others.
I din' mean compared to other shrooms. I know less about shrooms than I do about weed. I guess I meant how strong is the reaction effect vs weed.

Oh... and late edit add: Is it a painkiller like weed?
 

bigsur51

On a mailtrain.
Premium user
Veteran
420club
I din' mean compared to other shrooms. I know less about shrooms than I do about weed. I guess I meant how strong is the reaction effect vs weed.

Oh... and late edit add: Is it a painkiller like weed?



great questions Unca….you are entering into the Realm of the World of Psychedelia….

closely linked to one’s pineal gland and a tool in the decalcifying of the pineal gland


What is a Psychedelic Drug?​

The term psychedelic was created by English psychologist and researcher Humphry Osmond. He derived it from the Greek words for mind or soul (psyche) and show (deloun) to describe the effect LSD had on the mind. Osmond first used the word in a presentation he gave at the New York Academy of Sciences in 1957.1

Basically, there are two ways to figure out if a drug is psychedelic. The first is based on its receptor binding. The second is to compare the effects of the drug to what are considered psychedelic effects. If a compound passes the test for either or both, then it is psychedelic.

In terms of receptors, scientists classify a drug as psychedelic if it binds to serotonin 5-HT2A receptors (5-HT2AR) as an agonist or partial agonist2–4 (these are typically tryptamine compounds which are chemically similar to serotonin). The hallucinogenic effects of agonist binding are mediated via the 5-HT2AR receptor-coupled signaling pathway.2,3 This pathway is not entirely understood, but researchers theorize that it involves activation of the enzyme phospholipase C leading to the formation of inositol phosphates and diglycerol (signaling molecules) which causes the release of calcium ions from the endoplasmic reticulum in the cell. The possibility also exists that other serotonin receptors may be involved in the overall psychedelic experience of a user.

Interestingly, the effects of psychedelic drugs are highly variable and may not be dose-dependent.4 With LSD, for example, low doses (about <100 µg) may cause some distortion of cognitive and sensory processes with the person remaining aware that the drug is causing the effects. Higher doses may “…transport the user to an alternate reality, where they lose contact with their everyday environment.” These are the transcendent or mystical experiences that represent states of consciousness that are profoundly altered from reality.

From a medical standpoint, it is now understood by researchers that having a mystical experience results in a dramatic improvement for patients using psychedelic-assisted therapy.5–8 However, the mystical phenomenon can occur when using almost any dose of a psychedelic as long as the set and setting have been optimized to promote an altered state of consciousness.4

THC and other compounds in cannabis that have been tested elicit their effects by binding as agonists or partial agonists on the cannabinoid receptors CB1 and CB2. Like the serotonin receptors, cannabinoid receptors belong to the G protein-coupled receptor (GPCR) family.

When it comes to 5-HT2AR, current research indicates THC binding may have a role in the development of schizophrenia in young adults with long-term cannabis use.9 This study found that in young mice, long-term exposure to THC “…induced a pro-hallucinogenic molecular conformation of the 5-HT2AR.” The researchers also observed “…exacerbated schizophrenia-like responses…” in the mice. These observations of the modification of 5-HT2AR by THC is not only a ground-breaking finding but it also adds to the evidence of cannabis being a psychedelic drug based on receptor binding.
 

bigsur51

On a mailtrain.
Premium user
Veteran
420club
I din' mean compared to other shrooms. I know less about shrooms than I do about weed. I guess I meant how strong is the reaction effect vs weed.

Oh... and late edit add: Is it a painkiller like weed?


as far as the pain killer question I can only speak from my experience and specifically my experience in regards to pain relief from chronic migraines…

it does help me deal with a migraine, somewhat similar to cannabis in that I still have the pain , but with mushrooms , I can “ move” the pain into another compartment of my brain where it is out of sight out of mind…

i trade the pain for a psychedelic experience which usually includes copious amounts of smiles and laughs , lots of colors , and some hallucinations depending on how much I consume…

smoking weed and consuming mushrooms create an entourage effect , a synergy and in my opinion , the two were made for each other….
 

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