donb5
Member
It's necessary to convert (decarboxylate) the acid forms THCA and CBDA, synthesized by the Cannabis plant, to THC and CBD for anti-cancer medicine to be effective or at full power. THC bonds with CB receptors, but it doesn't when in the form of the larger THCA molecules. CBD doesn't bond with CB receptors, but still is at maximum effectiveness when decarbed.
CBDA when cooking requires more time to decarboxylate to CBD than THCA requires to yield THC, both being subject to the same cooking temperature in a vessel. If it were possible to cook them each at a custom temp, THCA would take less heat to decarb to THC than the amount of heat necessary to decarb CBDA to CBD. Since they must both be cooked at the same temperature in the same vessel, THCA is maximally converted to THC while CBDA is still in the midst of decarboxylating.
This disturbs me as it means there will probably be significantly more CBN in the final oil product as a result of degradation of THC, since THC has to be 'overcooked' to decarb all the CBDA. Though CBN is a 5-carbon molecule like other cannabinoids, it's not synthesized in the plant; rather it's the breakdown product of THC. My concern is that CBN is associated with weed that's stale, has a tiring effect (some say produces headaches) and hasn't been studied so well as to cancer cell destruction (apoptosis), stopping angiogenesis (blood vessel formation) in cancer cells, and in turning off a gene that allows metastisis, and/or other cellular mechanisms that fight cancer.
So I am wondering should CBN take over some of the job of the relatively well studied THC? The way around this problem would be to decarb two separate strains, one high in THC and the other high in CBD, then combine the oils later on.
Anyone who is interested in this with something to say relating to cannabinoids, debarboxylating, CBN info, or other semi-intelligent, pls offer ur comments.
CBDA when cooking requires more time to decarboxylate to CBD than THCA requires to yield THC, both being subject to the same cooking temperature in a vessel. If it were possible to cook them each at a custom temp, THCA would take less heat to decarb to THC than the amount of heat necessary to decarb CBDA to CBD. Since they must both be cooked at the same temperature in the same vessel, THCA is maximally converted to THC while CBDA is still in the midst of decarboxylating.
This disturbs me as it means there will probably be significantly more CBN in the final oil product as a result of degradation of THC, since THC has to be 'overcooked' to decarb all the CBDA. Though CBN is a 5-carbon molecule like other cannabinoids, it's not synthesized in the plant; rather it's the breakdown product of THC. My concern is that CBN is associated with weed that's stale, has a tiring effect (some say produces headaches) and hasn't been studied so well as to cancer cell destruction (apoptosis), stopping angiogenesis (blood vessel formation) in cancer cells, and in turning off a gene that allows metastisis, and/or other cellular mechanisms that fight cancer.
So I am wondering should CBN take over some of the job of the relatively well studied THC? The way around this problem would be to decarb two separate strains, one high in THC and the other high in CBD, then combine the oils later on.
Anyone who is interested in this with something to say relating to cannabinoids, debarboxylating, CBN info, or other semi-intelligent, pls offer ur comments.