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Variances within Malawi Gold?

3dDream

Matter that Appreciates Matter
Veteran
C Qual - It sounds to me like you want something with what I call a "clear high". I've found it in a few places. DJ's beans can do it.

I don't know about how DJ feeds. Check the forum, I am sure it's in there.

Good luck!
 

C Qual

Member
That's interesting, "a clear high." Do each and every one of these properties that I've been describing: 1.improvement of short-term memory; 2.no munchies; 3.quick onset of effects – all fit into what you classify as a "clear high?"!!!!!

I haven't read anything anywhere about feeding seedlings, until after the seedling stage, when do you start, from your f13 micro grow, I deduced that you were following DJ's advice. Do you start with the first watering. I've been following J Cervantes pretty much in everything!!!???...
 

amoril

Member
C Qual - It is my understanding that THCV does not get you high at all. Sam Skunkman has a few posts on this.

the idea that THCV wont get you high is subjective....doesnt matter if Sam said it or not. High is a relative term

THCV is psychoactive. that is objective. What its effects are....well, who knows, exactly. Could actually be "unique" effects for everyone...some may not feel much of anything, while others get blasted.

I just dont see why we're going to spew that sam doesnt think it gets him high....and as a result, its pointless for any of us?
 

3dDream

Matter that Appreciates Matter
Veteran
I trust a guy who says he has smoked pure thcv more than a guy guessing it does something. Sure it is subjective. I really don't care what chemicals are in the weed, I have no way of testing the chemicals.

Here's some reading:

Evidence that the plant cannabinoid Δ9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist

In conclusion, we have obtained evidence from competitive binding and GTPγS-binding experiments with mouse brain and CHO-hCB2 cell membranes that THCV is a competitive cannabinoid CB1 and CB2 receptor antagonist. In line with this hypothesis, THCV antagonized THC in the mouse isolated vas deferens, in a manner that suggested that it was competing with THC for CB1 receptors.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751228/

and one more:
GW Pharmaceuticals has bred a plant strain rich in THCV (tetrahydrocannabivarin) that it hopes will provide a natural antagonist drug that doesn't have the liabilities of Sanofi's synthetic. GW is the British pharmaceutical company that in 2005 won conditional approval in Canada to sell a plant extract called Sativex as a treatment for pain caused by multiple sclerosis.

Anecdotal evidence from seed collectors suggested that strains high in THCV had notably "clearer" and "faster" effects than high-THC strains, and GW decided to sponsor a pharmacological study by Roger Pertwee, MD, of the University of Aberdeen. Pertwee determined that THCV strongly Antagonizes anandamide -one of the body's own cannabinoids- while hardly antagonizing the plant cannabinoid THC! "The discovery that THCV was a neutral antagonist at the CB1 and then the CB2 receptor was a complete surprise," according to GW chairman Geoffrey Guy, MD. "It is therefore unlikely to be psychoactive at all in humans.

Even more intriguing was the fact that THCV antagonizes THC far less than endogenous (anandamide) or synthetic cannabinoids."

Apparently the cannabis plant contains and makes available to the body a choice of drugs and the body uses those it needs to achieve a balanced state (homeostasis). 3If the body is producing endocannabinoids in excess, it can use the plant cannabinoid THCV to achieve homeostasis,2 Guy observes. 3If the endocannabinoid system needs a boost, the THC provides it (while the THCV shuts down the endocannabinoid system, giving it a rest as it were). The key to relief, apparently, is not high cannabinoid levels but proper gradients.2

GW has developed a strain with a cannabinoid content of 85% THCV and 15% THC. (It may not be possible to have a plant that expresses 100% of its cannabinoid content as THCV.) Guy says, "the possibility exists (yet to be demonstrated) that the extract might inhibit the endogenous cannabinoids whilst maintaining basic cannabinoid tone through the effects of THC (albeit less potently than when unopposed by THCV). More pharmacology is underway and we hope to take this extract into man this year."

GW's goal is a preparation that curbs hunger but does not drive tumor formation, exacerbate MS cases, lower seizure thresholds or produce anxiety and depression. "You want a drug that takes the edge off, not one that hits you like a ton of bricks," says a GW researcher who hopes that Sanofi's campaign to educate doctors and the public about metabolic syndrome will create a market for his company's kinder, gentler cannabioid-antagonist drug.


ok, now you show me something that says pure THCV gets you high.
 

C Qual

Member
I know, I think that's really funny. I think that everyone acknowledges that Sam is the authority on things that he has done, not things common to the common man....
I think that growing cannabis in the quantities that he describes, sounds idilic, but its only practical for about .0001% of the population.
I do see some common effects reported by people who have smoked cannabis that has high THCV and maybe the clear high could be a THCV signifier. I'd really like to establish some positive early identifiers for people that want high THCV, without having to resort to a GC test. I wouldn't trust anyone else's GC test anyway.
 

C Qual

Member
Ok, I personally didn't say that it(THCV) gets you high. Think of it as "regulating your high." Here's my knowledge. THCV is a cb1 antagonist. A plant – high in THCV, will typically have a significant amount of THC as well. The THCV does NOT negate(antagonise) the cb1 receptor to the point of completely blocking off all the THC. If it did, that would make THCV an inverse agonist, however, as well, there is cb2 for the THC to activate to a lesser level. THCV doesn't block at all on cb2. It only acts on cb1. I love your avatar!!!
 

amoril

Member
spot on c qual. additionally, mecholaum has reported, within the last few years, that THCV antagonizes the endogenous cannabinoids moreso than, say, THC.

3ddream the fourth paragraph of your second provided quote also supports this....and none of it contradicts what we are talking about...?

We both agree that the term "high" is used subjectively. Do we disagree that THCV is a psychoactive compound? By definition, it does alter the chemical and thusly physical processes of the brain....so it is psychoactive.

how it effects each person will be different, even by your own evidence, as we all have a unique endogenous cannabinoid profile....just as our plants have a unique profile ;)

someone with lower levels of anandamide will certainly think THCV detracts from the "high", while someone with higher levels of anandamide may notice drastic effects.
 

C Qual

Member
spot on c qual. additionally, mecholaum has reported, within the last few years, that THCV antagonizes the endogenous cannabinoids moreso than, say, THC. Fu-show!!!!!

(someone with lower levels of anandamide will certainly think THCV detracts from the "high", while someone with higher levels of anandamide may notice drastic effects.)
This needs to be clarified since endogenous cannabinoids are created within the body on demand
...there is a basal ecs(endocannabinoid system) level, there is not a basal ec(endocannabinoid) level. Only if you are talking about a "starting" level of Anandamide at the exact time the drug enters the system. Anandamide levels vary within a day. Each individual's
anandamide producing system(the ECS) shouldn't vary greatly in it's tendencies, under stable conditions, ...probably how and why yogis try to remain on an even keel, once they find Nirvana. I have made the same mistake on thinking that there is a measureable, basal endocannabinoid level.
 

C Qual

Member
I actually just realized that (there is cannot be a concrete basal ec(endocannabinoid) level) upon seeing your judgement here. There have been tests that determine anandamide levels. They(researchers) point to a basal EC level. They even say that black people have higher anandamide levels, in the most prominent study!!! Amoril, Don't you think that a personal anandamide level is a little bit misleading. At best, I'd say there might be certain tendencies, as to the levels, I'm sure that my anandamide level changes the minute I even think about medicine. The levels can change instantly from things like satiety and paranoia. That may be why a high becomes more intense during a bout of P... more anandamide is produced?
So, I hope we can find some reliable way to measure THCV in early plants other than GC? THC is so easy. I wonder if low stress enhances THCV production.
 

amoril

Member
well, then that would just mean that the effects of the smoke could be more variable each time you smoke it, given a higher amount of THCV. It would variably antagonize the endogenous and the plant systems, depending upon the individuals current state...right?

I would think that could be seen as a benefit for frequent users.
 

C Qual

Member
I'm a little confused on what you are saying, now?? The variables are there, whether it is THC or THCV. The Endogenous C system is variable. Endogenous cannabinoids are created on demand.
You can change your high by changing your state before getting high. Working yourself into a paranoia on purpose would create more anandamide, ...hunger creates more anandamide. I guess that might be why you get higher on an empty stomach and purposeful paranoia in order to get higher would fall under the category of set and setting!
 

3dDream

Matter that Appreciates Matter
Veteran
We both agree that the term "high" is used subjectively. Do we disagree that THCV is a psychoactive compound? By definition, it does alter the chemical and thusly physical processes of the brain....so it is psychoactive.

Are you a lawyer? Geez! Do I think THCV alone can get you high? No. Do I think THCV can shape a high? Yes.

I was mainly responding to this w/ my pasting of info:
the idea that THCV wont get you high is subjective
This is where the confusion lies. If you meant pure THCV you are 100% wrong.

I am glad we are all on the same page now. :)

C Qual - I have found many clear-headed, zero munchies, fast acting plants in DJ's f13. He breeds for the high, not many can say that. I am looking for "pleasantly potent" types.
 
G

GroMore

C Qual - It is my understanding that THCV does not get you high at all. Sam Skunkman has a few posts on this.

This brings up an interesting issue, that of synergy. Synergy is where something interacts with other components to create an effect that wouldn't occur on the basis of the individual components. It is often referred to in nutritional science and is certainly a realistic and feasable possibility when you take accompanying cannabinoids into account.

But if we skip the techno stuff for just a moment, many can attest that Malawi is a strain that stands out from the crowd for its unique high. I've been growing it for years now and it really delivers a very high high and probably one of the nearest things to a cocaine buzz that I've encountered amongst most landrace sativas. I began growing in 1976 and have only had the oddest memory of anything that compared to it in the sense of the sort of high I'm referring to.

Go do blood tests, measure atomic radiation levels, stand on your head and see if the world is still up the right way or whatever. You can argue till the cows come home but you need to just go away and smoke some first, then come back and give a direct rave on it. I'm in a position to do that; wish you could too so that we could have a directly informed discussion on the matter.

GroMore
 

oldbootz

Active member
Veteran
Afropips information

"Hi OB...and peace with you.

AFROPIPS circulated the attachment to most of our customers at the back end
of 08, confirming - Jimmy (Afroman, Malawi Jim) had indeed passed away and
business although would carry on.

If you would like to pass the word further, in remembrance of his name and
contribution to the cause?

Afroman.
Jimmy SNR."
 

C Qual

Member
.......the lawyerness of amoril! That's funny. I think that people who investigate and read a lot of scientific data might come off that way.. It's funny. I wish that I could test Malawi, as well. I'm definitely not in it for the high, as much as the health benefits that I've been describing. But I am excited by what you say about Malawi, because I do enjoy the happy side effects of cannabis. Taking meds that make us feel anything other than good, can be completely obsolete now for everyone – legally!!. ...fun getting healthy.!!! Gro more, thank you so much for your observations on Malawi. ...not quite so concerned about the quality of the high – more just the traits of the effects. I did try some about 2 weeks ago and it was "style fine," in regards to the traits of a THCV strain. I'm just looking for some growing techniques here that people might have discovered to get more THCV.
3rd Dream, My guess is that DJ's F13 would measure high in THCV.
Please, if you get a chance ask DJ if he knows how to get more "V." ..in his "T." If you get a chance, please ask him about it.!!! I don't know if he's ever talked about testing his progeny by G. Cromotograph.
And Gro more, maybe you're right that I should go away and stop beating this.. But I want to thank you all – amoril, 3rd dream, OB, Spliphy, Thule, for your help. I was able to come to some really good realizations from your kind help and time!!!!!!!!!!!!!. I'll be here if you need anything about THCV, I guess we're breaking new ground here!!!! That feels good! I hope you find our communicattion practical and useful at some point. ...I do!
 
S

spliphy

changed viewpoint

changed viewpoint

"early cultivated" is: maturation of this Sativa is "early" as compared with other Sativas...provided it is "cultivated"...that is: subjecting it to an artificial veg. cycle and then a strict flower regimen.After rereading as one poster has suggested:joint:

upon further investigation: this is how I read "early"

upon reading his site...he claims earliness by cultivation carried out for some years by "the best"...so: "selection for earliness" is how I read it now:2cents:

he seems to strongly diss "cobs" without providing documentation...to me (maybe only to me)...good land-race genetics may be provided by these sources...anyway...not to clog the thread...I may start a thread about "cob" genetics
 

C Qual

Member
Mr Spliphy you are 100% correct. It is obvious, now.! You've opened my eyes right now. Look at this entire thread and peoples experiences and you will come to the conclusion like I did, "all.....ALL, early harvested marijuana (regardless of strain)is high in THCV, ...!
 
S

spliphy

sorry to hear about Malawi Jim

sorry to hear about Malawi Jim

in the spirit of preserving genetics, Jim would ultimately support (I believe) utilization of Malawi's strains whether they were "worked" or not
 
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