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    It's an established scientific fact, whether it's true or not. The hemisuccinate ester is the usual suppository form of THC.
    In the clinical field, the practical application of these substances must be awaited with the usual necessary patience. - Roger Adams
    Marihuana
    February 19, 1942

    Comment


      I read up it's Vitamin E in a certain format. Looked it up on where you can buy..can't find it.

      What would I be looking for if I wanted to buy tocopherol hemisuccinate?
      I'm new to the game.

      Comment


        Originally posted by G.O. Joe View Post
        It's an established scientific fact, whether it's true or not. The hemisuccinate ester is the usual suppository form of THC.
        How is something a known fact, weather its true or not. Sort of defeats the concept of being a fact. And how about many studies stating otherwise?
        Its a weed it will grow.

        Comment


          Originally posted by G.O. Joe View Post
          It's an established scientific fact, whether it's true or not. The hemisuccinate ester is the usual suppository form of THC.
          So you have stated nothing but scientific trial without anything to back it up.

          What is your own opinion on the use of suppositories regarding cannabis research??

          The Tribe
          LostTribe

          C99 The Ultimate Search and Rescue Mission
          https://www.icmag.com/ic/showthread.php?threadid=334331

          Treating Cancer with Concentrates
          https://www.icmag.com/ic/showthread.php?t=301121

          Comment


            Originally posted by Mednugs View Post
            I considered using nut oil but worried about a nut allergy. I can see that feedback report... I put in the suppository and everything was on fire!
            Hee, hee, hee, when we were making suppositories, one of my partners insisted on making some with HAO, which she alone tried, and reported back that it was a super hot ride.

            Good point on the nut oils! Not for everyone.
            An age is called Dark not because the light fails to shine, but because people refuse to see it.

            Believing is seeing and ignorance is bliss until it bites you in the ass!

            Fervor is the weapon of the impotent. The harder the sell, the poorer the product.

            Alas, my ignorance abounds; the more I've learned, the less I know that I know..........

            Thou shalt seek and respect the opinions of operators, even unto the third helper, for theirs is a wisdom unknown to technicrats.

            Wise men learn more from fools, than fools from wise men.

            In my dotage I finally discovered that the secret to putting on pants both legs at a time is sitting down.


            https://graywolfslair.com/

            Comment


              Originally posted by G.O. Joe View Post
              Butt dope research always uses esters, because THC was not absorbed in monkeys once and no one has ever contradicted that in a peer reviewed journal or the THC suppository patents. The Dr. appears to be oblivious to all that, so don't count on that emergency rectal CBD administration either.
              Ummm, 200 mg of cannabis absolute in a coco butter suppository certainly demonstrated THC effects when I personally tested it and the cancer patients we've made them for report effects as well.

              Hee, hee, hee, wait till I tell you where we all stuck them!
              An age is called Dark not because the light fails to shine, but because people refuse to see it.

              Believing is seeing and ignorance is bliss until it bites you in the ass!

              Fervor is the weapon of the impotent. The harder the sell, the poorer the product.

              Alas, my ignorance abounds; the more I've learned, the less I know that I know..........

              Thou shalt seek and respect the opinions of operators, even unto the third helper, for theirs is a wisdom unknown to technicrats.

              Wise men learn more from fools, than fools from wise men.

              In my dotage I finally discovered that the secret to putting on pants both legs at a time is sitting down.


              https://graywolfslair.com/

              Comment


                Just don't eat them. That was a bad idea.
                Its a weed it will grow.

                Comment


                  Patient swore she saw the Chupacabra, but we thick she might have been hallucinating. One that note we worked on improving the taste so it would be better as a sublingual.
                  Its a weed it will grow.

                  Comment


                    Originally posted by Mednugs View Post
                    How is something a known fact, weather its true or not.
                    When it's published in a respected science journal, which heavyweights in the field then cite when making statements in their own work like THC itself totally lacks bioavailability from suppositories, accompanied by statements like these from U.S. Pat. 4,933,363:

                    Studies have shown that there was no absorption, consequently no bioavailability achieved via the rectal route using various suppository formulations.

                    Neither delta-9-tetrahydrocannabinol nor its metabolite was detected in any of the blood samples, confirming the lack of bioavailability of delta-9-tetrahydrocannabinol itself from a suppository dosage form.


                    Originally posted by Gray Wolf View Post
                    Ummm, 200 mg of cannabis absolute in a coco butter suppository certainly demonstrated THC effects when I personally tested it and the cancer patients we've made them for report effects as well.
                    This then is a golden opportunity for the crew to get published in at least an open-access journal, to everlasting fame. Wouldn't young biochemistry student Joe be stoked to write the first science showing THC or metabolites in the blood of a posse of primates after - sorry, none before - a mass anal insertion of THC party?
                    In the clinical field, the practical application of these substances must be awaited with the usual necessary patience. - Roger Adams
                    Marihuana
                    February 19, 1942

                    Comment


                      Ok enough anal probing activity going on in here to get us all banned, just kidding!

                      So go joe are you stating that you believe suppositories will get thc into the blood stream in humans or not?

                      Have you tried it yourself as gw had(not sure I would be that brave unless I was very ill)?
                      LostTribe

                      C99 The Ultimate Search and Rescue Mission
                      https://www.icmag.com/ic/showthread.php?threadid=334331

                      Treating Cancer with Concentrates
                      https://www.icmag.com/ic/showthread.php?t=301121

                      Comment


                        Originally posted by Gray Wolf View Post
                        Ummm, 200 mg of cannabis absolute in a coco butter suppository certainly demonstrated THC effects when I personally tested it and the cancer patients we've made them for report effects as well.

                        Hee, hee, hee, wait till I tell you where we all stuck them!

                        So, where'd ya'll stuck em?
                        LostTribe

                        C99 The Ultimate Search and Rescue Mission
                        https://www.icmag.com/ic/showthread.php?threadid=334331

                        Treating Cancer with Concentrates
                        https://www.icmag.com/ic/showthread.php?t=301121

                        Comment


                          Originally posted by LostTribe View Post
                          So, where'd ya'll stuck em?
                          Dark dank places, where the sun doesn't shine, though there is nothing in them, except for the mental image, precluding eating them.
                          An age is called Dark not because the light fails to shine, but because people refuse to see it.

                          Believing is seeing and ignorance is bliss until it bites you in the ass!

                          Fervor is the weapon of the impotent. The harder the sell, the poorer the product.

                          Alas, my ignorance abounds; the more I've learned, the less I know that I know..........

                          Thou shalt seek and respect the opinions of operators, even unto the third helper, for theirs is a wisdom unknown to technicrats.

                          Wise men learn more from fools, than fools from wise men.

                          In my dotage I finally discovered that the secret to putting on pants both legs at a time is sitting down.


                          https://graywolfslair.com/

                          Comment


                            Originally posted by LostTribe View Post
                            Have you tried it yourself as gw had(not sure I would be that brave unless I was very ill)?
                            I couldn't in good faith give them to a patient without trying them myself, but haven't done followup trials, because I didn't much care for the insertion part.

                            I turned down the HAO suppository trials because of my suspicion that the cinnamon and myrrh might add entourage effects, significantly altering the experience.

                            I'm pleased to say, that was a good call, as the experimenter who did, reported quicker uptake, but seriously unpleasant side effects involving perceived heat.
                            An age is called Dark not because the light fails to shine, but because people refuse to see it.

                            Believing is seeing and ignorance is bliss until it bites you in the ass!

                            Fervor is the weapon of the impotent. The harder the sell, the poorer the product.

                            Alas, my ignorance abounds; the more I've learned, the less I know that I know..........

                            Thou shalt seek and respect the opinions of operators, even unto the third helper, for theirs is a wisdom unknown to technicrats.

                            Wise men learn more from fools, than fools from wise men.

                            In my dotage I finally discovered that the secret to putting on pants both legs at a time is sitting down.


                            https://graywolfslair.com/

                            Comment


                              Originally posted by Gray Wolf View Post
                              I couldn't in good faith give them to a patient without trying them myself, but haven't done followup trials, because I didn't much care for the insertion part.

                              I turned down the HAO suppository trials because of my suspicion that the cinnamon and myrrh might add entourage effects, significantly altering the experience.

                              I'm pleased to say, that was a good call, as the experimenter who did, reported quicker uptake, but seriously unpleasant side effects involving perceived heat.
                              This is science in its finest moment. We know that cinnamon and myrrh cause a burning sensation when in the oral cavity, so we can hypothesize that a similar effect will occur in the rectal cavity. I better call in a test subject for this..... moments later... hypothesis confirmed!

                              Comment


                                When explain this...
                                http://www.greenbridgemed.com/rectal...-cannabinoids/http://http://www.greenbridgemed.com...-cannabinoids/
                                Its a weed it will grow.

                                Comment

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