How Are Omega-3s Connected to the Endocannabinoid System?
As mentioned above, endocannabinoids are lipids made from the cells’ omega-3 and omega-6 content. Once cells build up a sufficient inventory of these fatty acids, endocannabinoids are created rapidly and as-needed in response to brain activity and stimuli (like stress and exercise).
Omega-3s are directly involved in the synthesis of endocannabinoids, and also react with existing endocannabinoids to create omega-3-derived endocannabinoid epoxides (which have powerful anti-inflammatory properties). Due to the important role that omega-3s have in the cell membrane, researchers believe that omega-3s also serve as crucial anchors for endocannabinoid cell membrane receptors .
To put it simply, omega-3s and endocannabinoids are totally dependent on each other in a healthy brain and body. This connection can also help explain why the noted anxiety and pain relieving effects from taking CBD oil are similar to the results achieved from receiving adequate omega-3 supplementation over time.
What Happens When You Don’t Get Enough Omega-3s?
Omega-3 deficiency is widespread in today’s world, impacting some 95% of adults in the United States . As researchers have demonstrated, this deficiency has serious consequences for the healthy functioning of our endocannabinoid systems.
Omega-3-deficient diets don’t just limit the creation of beneficial endocannabinoids and the omega-3-derived endocannabinoid epoxides. Studies have also shown that omega-3-deficiency creates dysfunctional endocannabinoid receptors, uncoupling them from the protein and altering signaling pathways in the brain .
Health Consequences of Omega-3 Deficiency
Consequences of dysfunctional endocannabinoid receptors (due to omega-3 deficiency) include increased anxiety and impaired behavior, according to one mice study from the University of Bordeaux . In addition, studies also show that omega-3 deficiency plays a role in increasing the development of obesity through the dysregulation of the endocannabinoid system .
Chronic deficiency of omega-3s in our diet may partly explain society’s enormous craving for CBD products. What’s more, it may also help to explain the widely-diverse experiences that CBD users have. After all, if one person’s endocannabinoid receptors are dysfunctional, throwing lots of cannabinoids at them won’t necessarily produce the results users are hoping to achieve.
So, it helps the body absorb the CBD far more than taking alone. When I used to buy capsules (full spectrum) before making my own CBD capsules, it was recommended.
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