couch lock CBD/CBN?

[lr3]

i heated some dried bluedream sugar leaves/trim at 200F for 2 hours. tried smoking a little and it tastes very hashy, and has a pretty intense couch lock. now can anyone clarify why letting a strain go longer or over decarboxylating to where some THC gets converted to CBN--why would this result in more couch lock if it is CBD that causes it?

i've seen it written and seems pretty much accepted that the more THC breaks down, the more CBN ends up in the finished product--causing couchlock though i've also read that CBD is supposed responsible for that effect.

can anyone clarify? i'm seeing the effect but want to better understand why higher CBN seems to result in more couch lock.

 

[aridbud]

According to Wikipedia (there are others here 'in the know' about this subject...Sam_Skunkman, others).....


As you know different components of cannabis affect us different ways in different brain receptors...

Wikipedia: "CBN is the primary product of THC degradation, and there is usually little of it in a fresh plant. CBN content increases as THC degrades in storage, and with exposure to light and air. It is only mildly psychoactive. Its affinity to the CB2 receptor is higher than for the CB1 receptor"

CB1:Cannabinoid receptor type 1 (CB1) receptors are thought to be one of the most widely expressed G protein-coupled receptors in the brain. This is due to endocannabinoid-mediated depolarization-induced suppression of inhibition, a very common form of short-term plasticity in which the depolarization of a single neuron induces a reduction in GABA-mediated neurotransmission

CB2 receptors are mainly expressed on T cells of the immune system, on macrophages and B cells, and in hematopoietic cells. They also have a function in keratinocytes. They are also expressed on peripheral nerve terminals. These receptors play a role in antinociception, or the relief of pain. In the brain, they are mainly expressed by microglial cells, where their role remains unclear.

So in essence, CBN helps with pain relief in the receptors role.

 

[devilgoob]

I say the entourage breaks down and you're left with a barebones THC,CBD and CBN high.

I've also had this happen in very, very degraded weed. It was kind of an intense high!


It had even been in a container under the sunlight alot of the time. Maybe *a lot* of THC broke down to CBN.

 

[m314]

I've made edibles, oil, and tinctures with some 6 and 7 year old trim. I didn't get it tested, but I'm guessing it was high in CBN. The main effect was a strong couch lock feeling with a strong body buzz. My gf at the time said it made her feel like a peach. Fuzzy all over. The head effect was kind of a blunt feeling instead of a high, not enjoyable on its own. It does feel nice when mixed with something high in THC.

 

[Sadhu Sciences]

CBN relieves pain, is a sleep aid, and supresses muscle spasms. This may be the couchlock effect you are looking for.

CBD is much more versatile in treating many of the ailments cannabis is said to help with almost across the board. This includes, anti-fungal, anti-bacterial, seizures, psoriasis, anti-spasmodic, etc..

I personally use CBD in oil, tincture, and flower form every night. Just imagine a 6 month cured CBD bud ? Its more about the ratios of THC to CBD. This is where you fill find the perfect balance you are looking for. Right now I am burning on a 3:1, 2:1, and a 1:1 ratio. Percentages are definitely important, but these ratios are the future of cannabis genetics IMO, once again , all opinion, and one can contradict. Have a great day !! Namaste

 

[lr3]

According to Wikipedia (there are others here 'in the know' about this subject...Sam_Skunkman, others).....


As you know different components of cannabis affect us different ways in different brain receptors...

Wikipedia: "CBN is the primary product of THC degradation, and there is usually little of it in a fresh plant. CBN content increases as THC degrades in storage, and with exposure to light and air. It is only mildly psychoactive. Its affinity to the CB2 receptor is higher than for the CB1 receptor"

CB1:Cannabinoid receptor type 1 (CB1) receptors are thought to be one of the most widely expressed G protein-coupled receptors in the brain. This is due to endocannabinoid-mediated depolarization-induced suppression of inhibition, a very common form of short-term plasticity in which the depolarization of a single neuron induces a reduction in GABA-mediated neurotransmission

CB2 receptors are mainly expressed on T cells of the immune system, on macrophages and B cells, and in hematopoietic cells. They also have a function in keratinocytes. They are also expressed on peripheral nerve terminals. These receptors play a role in antinociception, or the relief of pain. In the brain, they are mainly expressed by microglial cells, where their role remains unclear.

So in essence, CBN helps with pain relief in the receptors role.

Good information--makes sense. Is CBD also more active at the CB2 receptor? Sounds kind of like CB1 corresponds to the stimulation associated with THC, and CB2 is an inhibitory receptor. kind of like how amphetamines stimulate excitatory pathways (thru dopamine) whereas GHB or benzos activate GABA inhibitory receptors. it may be a bit of a stretch but seems to be analogous with the way other receptors work regarding excitatory or inhibitory action.

i had thought a possible reason for this would be that CBN competes for the same receptors and THC, and therefore may attenuate it's cerebral stimulation effects--or somehow alters the affects of THC and/or CBD.

I say the entourage breaks down and you're left with a barebones THC,CBD and CBN high.

I've also had this happen in very, very degraded weed. It was kind of an intense high!


It had even been in a container under the sunlight alot of the time. Maybe *a lot* of THC broke down to CBN.

this would make sense based on anecdotal evidence--as it is pretty much "common knowledge" in the growing community that the longer you let a grow go, the more couch lock it will produce. So I am assuming that there is some

I've made edibles, oil, and tinctures with some 6 and 7 year old trim. I didn't get it tested, but I'm guessing it was high in CBN. The main effect was a strong couch lock feeling with a strong body buzz. My gf at the time said it made her feel like a peach. Fuzzy all over. The head effect was kind of a blunt feeling instead of a high, not enjoyable on its own. It does feel nice when mixed with something high in THC.

yea, i have mixed high CBD/CBN material with high THC material--i like they way they can balance out the high to some degree.

CBN relieves pain, is a sleep aid, and supresses muscle spasms. This may be the couchlock effect you are looking for.

CBD is much more versatile in treating many of the ailments cannabis is said to help with almost across the board. This includes, anti-fungal, anti-bacterial, seizures, psoriasis, anti-spasmodic, etc..

I personally use CBD in oil, tincture, and flower form every night. Just imagine a 6 month cured CBD bud ? Its more about the ratios of THC to CBD. This is where you fill find the perfect balance you are looking for. Right now I am burning on a 3:1, 2:1, and a 1:1 ratio. Percentages are definitely important, but these ratios are the future of cannabis genetics IMO, once again , all opinion, and one can contradict. Have a great day !! Namaste

I agree it is probably more a function of the ratios of active cannabinoids (neglecting any terpene effects for this discussion). Are your ratios actually THC:CBD, or the ratio of high THC bud to High CBD bud used in your mix?

Lastly, does anyone know about how much it costs to get material tested? I'm in SoCal so assuming that the service is available here. I only grow enough for personal medicinal use. It would be nice to know what is in each grow but the cost is probably going to be pretty high for an end user like me.