Wiki Cannabinoids: http://en.wikipedia.org/wiki/Cannabinoid
Types
At least 85 cannabinoids have been isolated from the cannabis plant[5] To the right the main classes of natural cannabinoids are shown. All classes derive from cannabigerol-type compounds and differ mainly in the way this precursor is cyclized.
Tetrahydrocannabinol (THC), cannabidiol (CBD) and cannabinol (CBN) are the most prevalent natural cannabinoids and have received the most study. Other common cannabinoids are listed below:
Cannabigerol (CBG) is a non-psychoactive cannabinoid found in the Cannabis genus of plants. Cannabigerol is found in higher concentrations in hemp rather than in varieties of Cannabis with high THC content (the kind used as a drug).
Cannabigerol has been found to act as a high affinity α2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist.[1] It also binds to the CB2 receptor, but whether it acts as an agonist or antagonist at this site is unknown
Cannabichromene
Cannabichromene (abbreviated as CBC) is a cannabinoid found in the cannabis plant. It bears structural similarity to the other natural cannabinoids, including tetrahydrocannabinol, tetrahydrocannabivarin, cannabidiol, and cannabinol, among others. Evidence has suggested that it may play a role in the anti-inflammatory effects of cannabis, and may contribute to the overall analgesic effects of medical cannabis. However, more research into the compound may be needed before any definite medical effects can be verified.
Cannabicyclol
Cannabicyclol (CBL) is a non-psychotomimetic cannabinoid found in the Cannabis species. CBL is a degradative product like cannabinol. Light converts cannabichromene to CBL.
Cannabivarin
Cannabivarin, also known as cannabivarol or CBV, is a non-psychoactive cannabinoid found in minor amounts in the hemp plant Cannabis sativa. It is an analog of cannabinol (CBN) with the sidechain shortened by two CH2 groups. CBV is an oxidation product of tetrahydrocannabivarin (THCV, THV).
Tetrahydrocannabivarin
Natural occurrence
THCV is found in largest quantities in Cannabis sativa subsp. sativa strains. Some varieties that produce propyl cannabinoids in significant amounts, over five percent of total cannabinoids, have been found in plants from South Africa, Nigeria, Afghanistan, India, Pakistan and Nepal with THCV as high as 53.69% of total cannabinoids.[1] They usually have moderate to high levels of both THC and Cannabidiol (CBD) and hence have a complex cannabinoid chemistry representing some of the world's most exotic cannabis varieties.[2]
Pharmaceutical properties
It has been shown to be a CB1 receptor antagonist, i.e. blocks the effects of THC.[3] In 2007 GW Pharmaceuticals announced that THCV is safe in humans in a clinical trial and it will continue to develop THCV as a potential cannabinoid treatment for type 2 diabetes and related metabolic disorders, similar to the CB1 receptor antagonist rimonabant.[4]
Cannabidivarin
Cannabidivarine (CBDV), also known as cannabidivarol, is a non-psychoactive cannabinoid found in low amounts in Cannabis sativa. It is an analog of cannabidiol (CBD), with the side-chain shortened by two CH2 groups. Under acidic conditions it isomerizes into the psychoactive cannabinoid tetrahydrocannabivarin (THCV). CBDV is the Biosynthetic precursor of THCV in the plant.
Types
At least 85 cannabinoids have been isolated from the cannabis plant[5] To the right the main classes of natural cannabinoids are shown. All classes derive from cannabigerol-type compounds and differ mainly in the way this precursor is cyclized.
Tetrahydrocannabinol (THC), cannabidiol (CBD) and cannabinol (CBN) are the most prevalent natural cannabinoids and have received the most study. Other common cannabinoids are listed below:
- CBG Cannabigerol
- CBC Cannabichromene
- CBL Cannabicyclol
- CBV Cannabivarin
- THCV Tetrahydrocannabivarin
- CBDV Cannabidivarin
- CBCV Cannabichromevarin
- CBGV Cannabigerovarin
- CBGM Cannabigerol Monoethyl Ether
Cannabigerol (CBG) is a non-psychoactive cannabinoid found in the Cannabis genus of plants. Cannabigerol is found in higher concentrations in hemp rather than in varieties of Cannabis with high THC content (the kind used as a drug).
Cannabigerol has been found to act as a high affinity α2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist.[1] It also binds to the CB2 receptor, but whether it acts as an agonist or antagonist at this site is unknown
Cannabichromene
Cannabichromene (abbreviated as CBC) is a cannabinoid found in the cannabis plant. It bears structural similarity to the other natural cannabinoids, including tetrahydrocannabinol, tetrahydrocannabivarin, cannabidiol, and cannabinol, among others. Evidence has suggested that it may play a role in the anti-inflammatory effects of cannabis, and may contribute to the overall analgesic effects of medical cannabis. However, more research into the compound may be needed before any definite medical effects can be verified.
Cannabicyclol
Cannabicyclol (CBL) is a non-psychotomimetic cannabinoid found in the Cannabis species. CBL is a degradative product like cannabinol. Light converts cannabichromene to CBL.
Cannabivarin
Cannabivarin, also known as cannabivarol or CBV, is a non-psychoactive cannabinoid found in minor amounts in the hemp plant Cannabis sativa. It is an analog of cannabinol (CBN) with the sidechain shortened by two CH2 groups. CBV is an oxidation product of tetrahydrocannabivarin (THCV, THV).
Tetrahydrocannabivarin
Natural occurrence
THCV is found in largest quantities in Cannabis sativa subsp. sativa strains. Some varieties that produce propyl cannabinoids in significant amounts, over five percent of total cannabinoids, have been found in plants from South Africa, Nigeria, Afghanistan, India, Pakistan and Nepal with THCV as high as 53.69% of total cannabinoids.[1] They usually have moderate to high levels of both THC and Cannabidiol (CBD) and hence have a complex cannabinoid chemistry representing some of the world's most exotic cannabis varieties.[2]
Pharmaceutical properties
It has been shown to be a CB1 receptor antagonist, i.e. blocks the effects of THC.[3] In 2007 GW Pharmaceuticals announced that THCV is safe in humans in a clinical trial and it will continue to develop THCV as a potential cannabinoid treatment for type 2 diabetes and related metabolic disorders, similar to the CB1 receptor antagonist rimonabant.[4]
Cannabidivarin
Cannabidivarine (CBDV), also known as cannabidivarol, is a non-psychoactive cannabinoid found in low amounts in Cannabis sativa. It is an analog of cannabidiol (CBD), with the side-chain shortened by two CH2 groups. Under acidic conditions it isomerizes into the psychoactive cannabinoid tetrahydrocannabivarin (THCV). CBDV is the Biosynthetic precursor of THCV in the plant.