CovertCultivatr
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Anyone ever order this stuff?
JWH-018
From Wikipedia, the free encyclopedia
JWH-018
Systematic (IUPAC) name
Naphthalen-1-yl-(1-pentylindol-3-yl)methanone
Identifiers
CAS number 209414-07-3
ATC code ?
PubChem 10382701
Chemical data
Formula C24H23NO
Mol. mass 341.45 g/mol
Physical data
Solubility in water hydrophobic, n/a mg/mL (20 °C)
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Half life ?
Excretion ?
Therapeutic considerations
Pregnancy cat. ?
Legal status Schedule II (CA)
Routes ?
JWH-018 (1-pentyl-3-(1-naphthoyl)indole) is an analgesic chemical from the aminoalkylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors, with some selectivity for CB2.[1][2][3] It produces effects in animals very similar to those of THC itself, but with a longer duration of action.
On December 15th 2008, it was reported by the German pharmaceutical company THC Pharm, that JWH-018 was found as one of the active components in at least three versions of the herbal blend Spice, which has been sold as an incense, in a number of countries around the world since 2002. [4][5][6]
[edit]Effects
When smoked or ingested (orally), JWH-018 produces a very pleasant, euphoric feeling. Its effects are considered more of a general body high with unusually clear cerebral effects, similar to cannabis with a higher component ratio of sativa over indica. Some users have reported side effects, some similar to those of cannabis, such as nausea, increased heartbeat, and feelings of paranoia and anxiety. JWH-018 has also been described to be an efficient painkiller, numbing pains with stomach and headaches, along with tooth and joint pain. The duration is shorter than that of cannabis.
[edit]Common Dosage
The usual dosage for individual consumption (orally) varies greatly per individual but is typically between 3 and 20 milligrams. Dosage is not strictly sensitive to users' general tolerance to THC, however there seems to be a noticeable correlation per individual (unconfirmed) reports. When smoked (as opposed to consumed orally) the amount needed may be lower, however the observed effects have a lesser duration.
JWH-018
From Wikipedia, the free encyclopedia
JWH-018
Systematic (IUPAC) name
Naphthalen-1-yl-(1-pentylindol-3-yl)methanone
Identifiers
CAS number 209414-07-3
ATC code ?
PubChem 10382701
Chemical data
Formula C24H23NO
Mol. mass 341.45 g/mol
Physical data
Solubility in water hydrophobic, n/a mg/mL (20 °C)
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Half life ?
Excretion ?
Therapeutic considerations
Pregnancy cat. ?
Legal status Schedule II (CA)
Routes ?
JWH-018 (1-pentyl-3-(1-naphthoyl)indole) is an analgesic chemical from the aminoalkylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors, with some selectivity for CB2.[1][2][3] It produces effects in animals very similar to those of THC itself, but with a longer duration of action.
On December 15th 2008, it was reported by the German pharmaceutical company THC Pharm, that JWH-018 was found as one of the active components in at least three versions of the herbal blend Spice, which has been sold as an incense, in a number of countries around the world since 2002. [4][5][6]
[edit]Effects
When smoked or ingested (orally), JWH-018 produces a very pleasant, euphoric feeling. Its effects are considered more of a general body high with unusually clear cerebral effects, similar to cannabis with a higher component ratio of sativa over indica. Some users have reported side effects, some similar to those of cannabis, such as nausea, increased heartbeat, and feelings of paranoia and anxiety. JWH-018 has also been described to be an efficient painkiller, numbing pains with stomach and headaches, along with tooth and joint pain. The duration is shorter than that of cannabis.
[edit]Common Dosage
The usual dosage for individual consumption (orally) varies greatly per individual but is typically between 3 and 20 milligrams. Dosage is not strictly sensitive to users' general tolerance to THC, however there seems to be a noticeable correlation per individual (unconfirmed) reports. When smoked (as opposed to consumed orally) the amount needed may be lower, however the observed effects have a lesser duration.
