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Old 12-07-2018, 11:29 AM #1
Hubbleman
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What's the best way to invest mj for medical purposes?

Smoking, vaping or eadables ?


Ps. I meant injest / consume
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Old 12-07-2018, 12:43 PM #2
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oil
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Old 12-07-2018, 12:54 PM #3
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Concentrates? What's the best way to take concentrates??
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Old 12-07-2018, 02:35 PM #4
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Old 12-07-2018, 03:09 PM #5
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Smoking is the worst, the material is exposed to temperatures that cause organic compounds to become carcinogenic. Vape and dabbing would be the next best method. The flower/concentrate is not exposed to nearly as much heat, preserving more of the good compounds and not producing nearly as much negative ones, concentrates like the name implies is a concentration of the psychoactive and medical compounds only without the plant material (even concentrates heated at too high a temperature before inhaling releases carcinogens). Vapes and electronic nails offer the most consistent heating when inhaling and overall will be safest inhalation method. Edibles and topicals (lotion, oils etc) dont need to be heated before use/ingestion therefore being the cleanest method of intake.

Link to thread Toxicant Formation in Dabbing:
(Gray Wolf is one of the founders of Skunk Pharm Research, him and SkyHighLer are very knowledgeable with extraction and concentrates.)

https://www.icmag.com/ic/showthread.php?t=351896

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Old 12-07-2018, 03:14 PM #6
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Originally Posted by Switcher56 View Post
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My son takes CBD by gel pills. Easy peasy.


I like the fact that I can dose with oil to what I like, and stay there and functional for 6 hours. Lol

The high is also very different and cleaner than smoking for me.
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Old 12-07-2018, 04:07 PM #7
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Quote:
Originally Posted by TychoMonolyth View Post
My son takes CBD by gel pills. Easy peasy.


I like the fact that I can dose with oil to what I like, and stay there and functional for 6 hours. Lol

The high is also very different and cleaner than smoking for me.
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Old 12-07-2018, 05:00 PM #8
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canna pills
Do U need to decarboxylate concentrate / oil before u eat it up??
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Old 12-07-2018, 08:15 PM #9
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One of the most efficient ways I've researched is suppositories. You're bypassing the liver and sending it straight to the heart and lungs. The liver breaks a lot down of the cannabinoids, which means you're wasting 2/3rds of what you're eating.
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Old 12-07-2018, 08:40 PM #10
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Another method of bypassing the liver, This is what i do:

Sublingual products are the preferred method of treatment for many cancer patients who are taking full extract cannabis oil (sometimes referred to as “hemp oil” or Rick Simpson Oil). Direct sublingual application involves placing precisely decarboxylated cannabis under the tongue, allowing the cannabinoids to immediately enter the bloodstream through the vessel-rich tissues within the sublingual cavity. Before you swallow, cannabis can also enter the blood stream. Under the tongue and within the mouth there are a large number of blood vessels which can absorb cannabinoids Common examples of these type of medications include dissolvable strips, sublingual sprays, or medicated lozenges or tinctures. Sublingual delivery is not only a socially acceptable and convenient way to medicate, but intake through the oral mucosal membranes in your mouth is also a very effective way to ingest cannabinoids. This method provides for rapid and effective absorption directly into your systemic circulation because of the increased bioavailability of the cannabinoids.

Bioavailability is a subcategory of absorption in pharmacology that refers to the fraction of an administered dose of unchanged drug that reaches the blood stream. The only way to achieve true 100% bioavailability, by definition, is to administer a drug intravenously. Compared to other delivery methods, uptake through blood vessels and micro-capillaries in your mouth is one of the best ways to increase the bioavailability of cannabinoids. This “first-pass” of medication, as it’s referred to, allows the medication to avoid having to pass through your liver where it would be broken down making it significantly less beneficial and bioavailable Whenever you take any other medications orally – i.e. swallowing pills or eating an edible – a small fraction of that drug is metabolized in the liver before it even reaches systemic circulation (blood stream), thus decreasing the overall bioavailability of the medication. Additionally, sublingual delivery provides rapid effects similar to smoking
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