[Gray Wolf]

Hee, hee, hee, check this out. Dr Fischedick gave us permission to post this video of one of his lectures on cannabis terpenes. Check out this 2 1/2 hr video of his lecture and the following question and answer session!

https://thealchemistresource.thealchem istresource.com/p/normal-0-false-false-false_59.html

Not sure why this doesn't link up, but have Joe checking it out.

[SkyHighLer]

It's simple.

1. Click on the link above.

2. It will take you to a bad web page.

3. Then click in the address bar and use backspace to remove the s in https and the link should work.


troutman - https://www.icmag.com/ic/showpost.ph...2&postcount=29

[WaterFarmFan]

Thanks GW! Working through the video now. I found one of Dr. Fischedick's research papers that supports his talk with additional details:

Identification of Terpenoid Chemotypes Among High (−)- trans -Δ 9 - Tetrahydrocannabinol-Producing Cannabis sativa L. Cultivars

https://www.researchgate.net/publica...va_L_Cultivars

Edit - His 45 references for this study looks to be absolutely must reads for those, including me, seeking to understand cannabis from a deeper scientific point of view.

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2. Russo EB. History of cannabis and its preparations in saga, science, and sobriquet. Chem Biodivers. 2007;4:1614–1648.
3. Mead AP. International control of cannabis. In: Handbook of Cannabis (Pertwee R, ed.). Oxford University Press: Oxford, United Kingdom, 2014, pp. 44–64.
4. Maxwell JC, Mendelson B. What do we know now about the impact of the laws related to marijuana? J Addict Med. 2016;10:3–12.
5. Chatwin C. UNGASS 2016: insights from Europe on the development of global cannabis policy and the need for reform of the global drug policy regime. Int J Drug Policy. 2015 [Epub ahead of print]; DOI: 10.1016/i.drugpo.2015.12.17.
6. Room R. Legalizing a market for cannabis for pleasure: Colorado, Washington, Uruguay and beyond. Addiction 2014;109:345–351.
7. Schultes RE, Klein WM, Plowman T, et al. Cannabis: an example of taxonomic neglect. Botanical Museum Leaflets, Harvard University 1974;23:337–367.
8. Erkelens JL, Hazekamp A. An essay on the history of the term Indica and the taxonomical conflict between the monotypic and polytypic views of Cannabis. Cannabinoids. 2014;9:9–15.
9. Piomelli D, Russo EB. The Cannabis sativa versus Cannabis indica debate: an interview with Ethan Russo, MD. Cannabis Cannabinoid Res. 2016;1:44–46.
10. Hillig, KW. Genetic evidence for speciation in Cannabis (Cannabaceae). Genet Resour Crop Evol. 2005;52:161–180.
11. Turner CE, Elsohly MA, Boeren EG. Constituents of Cannabis sativa L. XVII. A review of the natural constituents. J Nat Prod. 1980;43: 169–234
12. ElSohly MA, Slade D. Chemical constituents of marijuana: the complex mixture of natural cannabinoids. Life Sci. 2005;78:539–548.
13. Radwan MM, ElSohly MA, Slade D, et al. Biologically active cannabinoids from high-potency Cannabis sativa. J Nat Prod. 2009;72:906–911.
14. Ahmed SA, Ross SA, Slade D, et al. Minor oxygenated cannabinoids from high potency Cannabis sativa L. Phytochemistry. 2015;117:194–199.
15. Ben Amar M. Cannabinoids in medicine: a review of their therapeutic potential. J Ethnopharmacol. 2006;105:1–25.
16. Costa B. On the pharmacological properties of Delta9-tetrahydrocannabinol (THC). Chem Biodivers. 2007;4:1664–1677.
17. Russo EB. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011;163:1344–1364.
18. Mechoulam R, Peters M, Murillo-Rodriguez E, et al. Cannabidiol—recent advances. Chem Biodivers. 2007;4:1678–1692.
19. Ferna´ndez-Ruiz J, Sagredo O, Pazos MR, et al. Cannabidiol for neurode-generative disorders: important new clinical applications for this phytocannabinoid? Br J Clin Pharmacol. 2013;75:323–333.
20. Schubart CD, Sommer IEC, Fusar-Poli P, et al. Cannabidiol as a potential treatment for psychosis. Eur Neuropsychopharmacol. 2014;24:51–64.
21. Mechoulam R. Plant cannabinoids: a neglected pharmacological treasure trove. Br J Pharmacol. 2005;146:913–915.
22. Fetterman PS, Keith ES, Waller CW, et al. Mississippi-grown Cannabis sativa L.: preliminary observation on chemical definition of phenotype and variations in tetrahydrocannabinol content versus age, sex, and plant part. J Pharm Sci. 1971;60:1246–1249.
23. Small E, Beckstead HD. Common cannabinoid phenotypes in 350 stocks of Cannabis. Lloydia 1973;36:144–165.
24. Hillig KW, Mahlberg PG. A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae). Am J Bot. 2004;91:966–975.
25. de Meijer E, The chemical phenotypes (chemotypes) of cannabis. In: Handbook of Cannabis (Pertwee RG, ed.). Oxford University Press: Oxford, United Kingdom, 2014, pp. 89–110.
26. Niesink RJM, Rigter S, Koeter MW, et al. Potency trends of D9-tetrahydrocannabinol, cannabidiol and cannabinol in cannabis in the Netherlands: 2005-15. Addiction 2015;110:1941–1950.
27. ElSohly MA, Mehmedic Z, Foster S, et al. Changes in cannabis potency over the last 2 decades (1995–2014): analysis of current data in the United States. Biol Psychiatry. 2016;79:613–619.
28. Fischedick JT, Hazekamp A, Erkelens T, et al. Metabolic fingerprinting of Cannabis sativa L., cannabinoids and terpenoids for chemotaxonomic and drug standardization purposes. Phytochemistry. 2010;71:2058–2073.
29. Elzinga S, Fischedick J, Podkolinski R, et al. Cannabinoids and terpenes as chemotaxonomic markers in cannabis. Nat Prod Chem Res. 2015;3:1–9.
30. Hazekamp A, Tejkalova ´K, Papadimitriou S. Cannabis: from cultivar to chemovar II—a metabolomics approach to cannabis classification. Cannabis Cannabinoid Res. 2016;1:202–215.
31. Russo E, Guy GW. A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. Med Hypotheses. 2006;66:234–246.
32. Bhattacharyya S, Morrison PD, Fusar-Poli P, et al. Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology. Neuropsychopharmacology. 2010;35:764–774.
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34. Brenneisen R. Chemistry and analysis of phytocannabinoids and other cannabis constituents. In: Marijuana and the Cannabinoids (ElSohly MA, ed.). Humana Press: Totowa, NJ, 2007, pp. 17–49.
35. Happyana N, Agnolet S, Muntendam R, et al. Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR. Phytochemistry. 2013;87:51–59.
36. Andre CM, Hausman JF, Guerriero G. Cannabis sativa: the plant of the thousand and one molecules. Front Plant Sci. 2016;7:19
37. Small E, Naraine SGU. Size matters: evolution of large drug-secreting resin glands in elite pharmaceutical strains of Cannabis sativa (marijuana). Genet Resour Crop Evol. 2016;63:349–359.
38. Fischedick J, Van Der Kooy F, Verpoorte R. Cannabinoid receptor 1 binding activity and quantitative analysis of Cannabis sativa L. smoke and vapor. Chem Pharm Bull. 2010;58:201–207.
39. Hazekamp A, Fischedick JT. Cannabis—from cultivar to chemovar. Drug Test Anal. 2012;4:660–667.
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41. Adams R. Identification of essential oil components by gas chromatography/mass spectrometry, 4th ed. Allured Pub Corp: Carol Stream, IL, 2007.
42. Bylesjo ¨M, Rantalainen M, Cloarec O, et al. OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification. J Chemometrics. 2006;20:341–351.
43. Xia J, Wishart DS. Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst. Nat Protocols. 2011;6:743–760.
44. Bijlsma S, Bobeldijk I, Verheij ER, et al. 2006. Large-scale human meta-bolomics studies: a strategy for data (pre-) processing and validation. Anal Chem. 2006;78:567–574.
45. Giese MW, Lewis MA, Giese L, et al. Development and validation of a reliable and robust method for the analysis of cannabinoids and terpenes in cannabis. J AOAC Int. 2015;98:1503–1522.

Mad props to this very smart cat!!!!

[Gray Wolf]

Yeah, we were impressed as well!

[Leaf Eater]

Hey Grey wolf, you have always helped us out, so this was the least I could do for the community thanks for sharing

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