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Old 06-06-2017, 05:50 PM #1
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Post Should Cannabis Be Avoided Before Age 25?


Research has also shown how THC affects the growth of electrical pathways and brain matter. The consensus seems to be that cannabis use is fine, but only after you have finished growing.

New Research Suggests You Shouldn’t Use Cannabis Before Age 25 By LA Lady | June 06, 2017

From infancy to the age of 25, the human brain goes through a dramatic growth process that solidifies the essence of a person: likes, dislikes, temperament, senses of touch and smell are all determined within the first five years of a human life. Within the teenage years, a person’s judgement begins to form that is independent of their intellect and academic abilities, and will be fully-formed around the age of 25. Therefore, any substance or environmental factor that could inhibit this development is discouraged by doctors.

While cannabis seems to have little effect on adult brains over 25, doctors are concerned by cannabis use among teenagers, and want to warn them on the dangers of using cannabis before the brain is ready. “You should know what you’re getting into. You should know what will happen,” said Jennifer Golick from Muir Wood Adolescent and Family Services in Marin County, CA. “Be an informed consumer — you make the choice.” Golick sees about 180 children as patients who have cannabis dependency and understands drug abstinence education has little effect on the teenage population.

In terms of recreational substances, alcohol, heroin, cocaine, tobacco, ecstasy and methamphetamine are far more lethal than cannabis. In fact, lethal overdoses of cannabis are non-existent due to how cannabis is processed in the human body and the amount needed to trigger an overdose. But doctors want teenage patients to know that a non-lethal substance can still be harmful.

According to Sion Kim Harris, a researcher at the Center for Adolescent Substance Abuse Research at Boston Children’s Hospital, teenagers involved in heavy cannabis consumption often have decreased neurocognitive function and brain development. This is due to THC’s effect on neurons in the hippocampus, decreasing their activity in a part of the brain responsible for memory and learning. If the hippocampus has prolonged exposure to THC during the developmental phase, it could lead to undersized development and therefore decreased function. Since a human brain doesn’t fully develop until the age of 25 or so, teenage brains are more easily-influenced by internal and external stressors, and are more adept at learning and adapting to new influences. If neurons in the hippocampus are less active over time, the brain naturally disables these neurons, which affects memory formation.
“That is one of the biggest issues for teens — the ‘opportunity cost,” Harris said. “Learning is the number one job for teens, and if they are having problems with learning, that will impact their ability to grow into adulthood.”
Research has also shown how THC affects the growth of brain matter, and how electrical pathways in the brain can be weaker. Myelin, the substance responsible for insulating neurons and other nerve cells, does not form as well in the presence of chronic THC consumption. “So the implication is your brain is slower.” said Harris.
“There’s a problem with cognitive processing. It’s not as sharp or as strong. It’s harder to maintain focus.”
There is also a connection between how early the brain is exposed to harmful substances and the severity of developmental damage. According to one report,
“The brain does not complete development until approximately age 25, and data from the field of alcohol use reflect that substance use exposure during this period when the brain undergoes rapid transformation could have a more lasting impact on cognitive performance.”
Researchers at the academy admit that there’s no clear connection between cannabis and academic performance, due to the infinite number of variables that affect cognitive brain development, they do suggest “this interference in cognitive function during the adolescent and emerging adult years, which overlap with the critical period in which many youth and young adults’ primary responsibility is to be receiving their education, could very well interfere with these individuals’ ability to optimally perform in school and other educational settings.”

But in teenager’s whose family has a history of mental illness, marijuana use could lead to a higher likelihood of that illness presenting itself. “We are seeing these kids develop schizophrenia at a younger age than their parents or other family members developed it,” Harris said. “Marijuana use seems to be a precipitating factor.”

The consensus seems to be that cannabis is use is fine, but only after you’re finished growing. “I don’t care who uses, or how often, if you’re over age 30,” said Harris. “But we’re seeing these critical developmental issues in people up to their mid-20s.”

LA Lady
The LA Lady covers cannabis culture from Southern California. Follow her on Twitter @the_LAlady. Email tips to marie@massroots.com.
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Old 06-06-2017, 07:17 PM #2
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Considering how essential our Endocannabiniod System (ECS) , waiting until one is 25 to consume cannabis seems misguided.

The pool of test subjects seems to be biased towards individuals with deeper underlying issues.

"Researchers at the academy admit that there’s no clear connection between cannabis and academic performance, due to the infinite number of variables that affect cognitive brain development,"
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Old 06-06-2017, 08:21 PM #3
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I call bs. There are no actually studies done. Maybe if cannabis ever gets reclassified I will believe these propaganda studies. Schedule 1 means no real testing. It's all hypotheses
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Old 06-06-2017, 08:42 PM #4
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Old 06-06-2017, 08:49 PM #5
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It makes me wonder what I may have become if I hadn’t started smoking pot before I was teenager, lol. Smoked all thru high school and college. Then I got a good job and now I own my own business.

I would really like to see some hard numbers these researchers are getting/using and where they’re coming from for them to make these hypotheses. I don’t condone use by kids but in reality I used when I was young. It really didn’t create any problems other than the associated social stigma…and I was lucky I never ran afoul with the law.

Speaking of Facebook and not to go off topic too much, but has anybody seen the clips of toddlers trying to expand pictures in magazines? Some moms don’t seem to be too concerned about letting their little ones use pads.
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Old 06-06-2017, 08:50 PM #6
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Old 06-06-2017, 09:00 PM #7
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Old 06-06-2017, 10:28 PM #8
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Starting age of marijuana use may have long-term effects on brain development


These are divergent patterns in overlapping areas of anterior prefrontal cortex. Credit: Center for BrainHealth

https://www.sciencedaily.com/release...0210135334.htm
Starting age of marijuana use may have long-term effects on brain development
Date:February 10, 2016 Source:Center for BrainHealth

Summary:The age at which an adolescent begins using marijuana may affect typical brain development, according to researchers. Scientists describe how marijuana use, and the age at which use is initiated, may adversely alter brain structures that underlie higher order thinking.

The age at which an adolescent begins using marijuana may affect typical brain development, according to researchers at the Center for BrainHealth at The University of Texas at Dallas. In a paper recently published in Developmental Cognitive Neuroscience, scientists describe how marijuana use, and the age at which use is initiated, may adversely alter brain structures that underlie higher order thinking.

Findings show study participants who began using marijuana at the age of 16 or younger demonstrated brain variations that indicate arrested brain development in the prefrontal cortex, the part of the brain responsible for judgment, reasoning and complex thinking. Individuals who started using marijuana after age 16 showed the opposite effect and demonstrated signs of accelerated brain aging.

"Science has shown us that changes in the brain occurring during adolescence are complex. Our findings suggest that the timing of cannabis use can result in very disparate patterns of effects," explained Francesca Filbey, Ph.D., principal investigator and Bert Moore Chair of Behavioral and Brain Sciences at the Center for BrainHealth. "Not only did age of use impact the brain changes but the amount of cannabis used also influenced the extent of altered brain maturation."

The research team analyzed MRI scans of 42 heavy marijuana users; twenty participants were categorized as early onset users with a mean age of 13.18 and 22 were labeled as late onset users with a mean age of 16.9. According to self-reports, all participants, ages 21-50, began using marijuana during adolescence and continued throughout adulthood, using cannabis at least one time per week.

According to Filbey, in typical adolescent brain development, the brain prunes neurons, which results in reduced cortical thickness and greater gray and white matter contrast. Typical pruning also leads to increased gyrification, which is the addition of wrinkles or folds on the brain's surface. However, in this study, MRI results reveal that the more marijuana early onset users consumed, the greater their cortical thickness, the less gray and white matter contrast, and the less intricate the gyrification, as compared to late onset users. These three indexes indicate that when participants began using marijuana before age 16, the extent of brain alteration was directly proportionate to the number of weekly marijuana use in years and grams consumed.

Contrastingly, those who began using marijuana after age 16 showed brain change that would normally manifest later in life: thinner cortical thickness, stronger gray and white matter contrast.

"In the early onset group, we found that how many times an individual uses and the amount of marijuana used strongly relates to the degree to which brain development does not follow the normal pruning pattern. The effects observed were above and beyond effects related to alcohol use and age. These findings are in line with the current literature that suggest that cannabis use during adolescence can have long-term consequences," said Filbey.

Filbey notes that a longitudinal study would be necessary to establish a causal relationship between brain alterations and marijuana use. Her future studies will explore cognitive and behavioral changes associated with structural brain change and consider the different patterns of development within the adolescent period and how these patterns could lead to non-linear effects.

Story Source:
Materials provided by Center for BrainHealth. Note: Content may be edited for style and length.

Journal Reference:

  1. Francesca M. Filbey, Tim McQueeny, Samuel J. DeWitt, Virendra Mishra. Preliminary findings demonstrating latent effects of early adolescent marijuana use onset on cortical architecture. Developmental Cognitive Neuroscience, 2015; 16: 16 DOI: 10.1016/j.dcn.2015.10.001
  2. Center for BrainHealth. "Starting age of marijuana use may have long-term effects on brain development." ScienceDaily. ScienceDaily, 10 February 2016. www.sciencedaily.com/releases/2016/02/160210135334.htm.

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Old 06-07-2017, 01:28 AM #9
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Most people are as dumb as dog shit, so how would you know anyway, lol
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Old 06-07-2017, 04:57 AM #10
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