FDA Approves Synthetic Weed - Medical Cannabis News - International Cannagraphic Magazine Forums

**yortbogey** · 07-28-2016, 10:43 PM

The U.S. Food and Drug Administration (FDA) has given its stamp of approval on synthetic weed for the first time. Earlier this month, the FDA approved the liquid formulation of dronabinol — a synthetic form of the psychoactive compound in cannabis: tetrahydrocannabinol (THC).

Popular Science reports that the synthetic liquid formulation will be sold under the name of Syndros and will be categorized as a Schedule III substance under the Controlled Substances Act. Falling under Schedule III means the liquid formula of dronabinol is for medical use, with low chances of abuse and addiction. In comparison, natural cannabis is classified as Schedule I, which makes it federally illegal and a substance considered to have a high potential for abuse.

Dronabinol has been available since the mid-1980s in a pill form (sold commonly under the brand Marinol) and has been prescribed to treat nausea and vomiting caused by chemotherapy and other cancer medications. What separates Syndros from Marinol is the formula and being a liquid means Syndros might be easier for patients to absorb.

“It is a liquid that is easy-to-swallow and allows for the dosage to be titrated to clinical effect,” says Insys Therapeutics, the parent company manufacturing both Marinol and Syndros, in a press release.

Marinol and Syndros are approved for treating chemotherapy induced nausea and weight loss related to AIDS. But there are some experts who are wary of synthetic cannabis, as it may have limitations. Dr. Perry Solomon, a medical marijuana physician and chief medical officer of HelloMD, told Motherboard that synthetic marijuana does not have the “entourage effect” where all the chemicals in the plant react with each other.

"I think it is really important to understand the difference between a preparation that has gone through clinical development and one that hasn't,” told Catherine Jacobson, director of clinical research at Canadian medical cannabis company Tilray, to Motherboard. “We would like to do research on whole plant extracts. One of the holdups is the lack of safe, reliable, consistent products that are not pharmaceutical products."

https://www.msn.com/en-us/news/us/fda...xmG?li=BBnb7Kz

Chimera · 07-28-2016, 11:36 PM

Dronabinol is actually THC, and it's not exactly accurate to call synthetic.... in the industry it has been referred to over and over again as semi-synthetic since it's created form a naturally produced molecule.

Dronabinol is created from cannabidiol extracted from hemp plants grown in Germany. The CBD is converted to THC chemically; they do this because it's legal to grow CBD containing hemp, but illegal to grow THC producing drug cannabis.

G.O. Joe · 07-29-2016, 05:30 AM

Insys is a registered manufacturer not importer, they told the DEA they'd make synthetic CBD and some would be for conversion to THC. It's a public company and their press releases say their CBD is homemade. The best synthesis for CBD doesn't seem to be patented. Maybe the Germans are selling them olivetol?

Current US federal law. (g) Hallucinogenic substances.

(1) Dronabinol (synthetic) in sesame oil and encapsulated in a soft gelatin capsule in a U.S. Food and Drug Administration approved product - 7369.
[Some other names for dronabinol: (6aR-trans)-6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo [b,d]pyran-1-ol] or (-)-delta-9-(trans)-tetrahydrocannabinol]

It's doubtful whether THC from natural CBD would really meet the synthetic part of the exception, or if the DEA would allow the importation of cannabinoid material for sale or synthesis. Marinol was originally and is probably still made from olivetol.

Maybe someone at msn knows someone holding Insys stock that's been tanking for months? The law obviously needs to change for Insys to actually sell this - maybe it will happen like the DEA is Insys' bitch - or the stock will keep tanking. The stock wouldn't be tanking if Insys made Marinol - not exactly a tablet - like the article says they do.

corky1968 · 07-29-2016, 05:44 AM

What's next? Fake steaks?

_tessarecting · 07-29-2016, 05:48 AM

Some lichens contain up to 30% olivetol.

And yeah corky the japanese can make burgers out of feces/sewage waste butt thats a whole different story

aridbud · 07-29-2016, 05:50 AM

Scary!!! And shows where their pockets are lined.....

aridbud · 07-29-2016, 05:51 AM

Quote:

Originally Posted by corky1968

What's next? Fake steaks?

Slim Jim's Beef jerky!

PoweredByLove · 07-29-2016, 07:05 AM

so the natural form is still illegal but manufactured into a pill/drops it's A-Ok right? anyway carry on #fuckingthepolice

idiit · 07-22-2017, 04:03 PM

Seven deaths in Kiwi synthetic cannabis epidemic this month

21 Jul, 2017 3:11pm
https://www.nzherald.co.nz/nz/news/ar...ectid=11893530

Betterhaff · 07-24-2017, 08:15 PM

^ ^ That’s a different thing…probably of the likes of “Spice” or “K2”. Still a shame people have died using that stuff, if weed where legal there would be no need for it.

07-28-2016, 10:43 PM	#1
yortbogey To Have More ... Desire Less Join Date: Sep 2008 Posts: 10,983	FDA Approves Synthetic Weed The U.S. Food and Drug Administration (FDA) has given its stamp of approval on synthetic weed for the first time. Earlier this month, the FDA approved the liquid formulation of dronabinol — a synthetic form of the psychoactive compound in cannabis: tetrahydrocannabinol (THC). Popular Science reports that the synthetic liquid formulation will be sold under the name of Syndros and will be categorized as a Schedule III substance under the Controlled Substances Act. Falling under Schedule III means the liquid formula of dronabinol is for medical use, with low chances of abuse and addiction. In comparison, natural cannabis is classified as Schedule I, which makes it federally illegal and a substance considered to have a high potential for abuse. Dronabinol has been available since the mid-1980s in a pill form (sold commonly under the brand Marinol) and has been prescribed to treat nausea and vomiting caused by chemotherapy and other cancer medications. What separates Syndros from Marinol is the formula and being a liquid means Syndros might be easier for patients to absorb. “It is a liquid that is easy-to-swallow and allows for the dosage to be titrated to clinical effect,” says Insys Therapeutics, the parent company manufacturing both Marinol and Syndros, in a press release. Marinol and Syndros are approved for treating chemotherapy induced nausea and weight loss related to AIDS. But there are some experts who are wary of synthetic cannabis, as it may have limitations. Dr. Perry Solomon, a medical marijuana physician and chief medical officer of HelloMD, told Motherboard that synthetic marijuana does not have the “entourage effect” where all the chemicals in the plant react with each other. "I think it is really important to understand the difference between a preparation that has gone through clinical development and one that hasn't,” told Catherine Jacobson, director of clinical research at Canadian medical cannabis company Tilray, to Motherboard. “We would like to do research on whole plant extracts. One of the holdups is the lack of safe, reliable, consistent products that are not pharmaceutical products." https://www.msn.com/en-us/news/us/fda...xmG?li=BBnb7Kz __________________ i got a river for a soul... Darlin' I'm a nightmare... Dressed like a daydream~~~
	Quote 2 members found this post helpful.

07-28-2016, 11:36 PM	#2
Chimera Genetic Resource Management Join Date: May 2006 Location: In vitro Posts: 2,383	Dronabinol is actually THC, and it's not exactly accurate to call synthetic.... in the industry it has been referred to over and over again as semi-synthetic since it's created form a naturally produced molecule. Dronabinol is created from cannabidiol extracted from hemp plants grown in Germany. The CBD is converted to THC chemically; they do this because it's legal to grow CBD containing hemp, but illegal to grow THC producing drug cannabis. __________________ More Agriculture Less Agro-Culture Last edited by Chimera; 07-29-2016 at 12:12 AM..
	Quote 5 members found this post helpful.

07-29-2016, 05:30 AM	#3
G.O. Joe Senior Member Join Date: Oct 2008 Location: Ditchweed City Posts: 1,117	Insys is a registered manufacturer not importer, they told the DEA they'd make synthetic CBD and some would be for conversion to THC. It's a public company and their press releases say their CBD is homemade. The best synthesis for CBD doesn't seem to be patented. Maybe the Germans are selling them olivetol? Current US federal law. (g) Hallucinogenic substances. (1) Dronabinol (synthetic) in sesame oil and encapsulated in a soft gelatin capsule in a U.S. Food and Drug Administration approved product - 7369. [Some other names for dronabinol: (6aR-trans)-6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo [b,d]pyran-1-ol] or (-)-delta-9-(trans)-tetrahydrocannabinol] It's doubtful whether THC from natural CBD would really meet the synthetic part of the exception, or if the DEA would allow the importation of cannabinoid material for sale or synthesis. Marinol was originally and is probably still made from olivetol. Maybe someone at msn knows someone holding Insys stock that's been tanking for months? The law obviously needs to change for Insys to actually sell this - maybe it will happen like the DEA is Insys' bitch - or the stock will keep tanking. The stock wouldn't be tanking if Insys made Marinol - not exactly a tablet - like the article says they do. __________________ In the clinical field, the practical application of these substances must be awaited with the usual necessary patience. - Roger Adams Marihuana February 19, 1942
	Quote 1 members found this post helpful.

07-29-2016, 05:44 AM	#4
corky1968 Banned Join Date: Oct 2006 Location: Living in a Trichome. These are the Best Homes in the World. Posts: 2,695	What's next? Fake steaks?
	Quote 1 members found this post helpful.

07-29-2016, 05:48 AM	#5
_tessarecting ஓ Join Date: May 2015 Posts: 3,852	Some lichens contain up to 30% olivetol. And yeah corky the japanese can make burgers out of feces/sewage waste butt thats a whole different story __________________
	Quote

07-29-2016, 05:50 AM	#6
aridbud automeister Join Date: May 2013 Location: the best place on earth Posts: 5,589	Scary!!! And shows where their pockets are lined..... __________________ Seeds have the power to preserve species, to enhance cultural as well as genetic diversity, to counter economic monopoly and to check the advance of conformity on all its many fronts. Michael Pollan Happiness held is the seed; Happiness shared is the flower. John Harrigan Instant gratification takes too long. Carrie Fisher - RIP. *afterthought autos* We are passionate breeders of unique quality cannabis autoflower hybrid seeds at down to earth prices; now 11 years running! https://www.icmag.com/ic/forumdisplay.php?f=65770
	Quote

07-29-2016, 07:05 AM	#8
PoweredByLove Most Loved Join Date: Oct 2015 Location: Throwin Bricks...Hittin Bitches... Posts: 1,241	so the natural form is still illegal but manufactured into a pill/drops it's A-Ok right? anyway carry on #fuckingthepolice __________________
	Quote

07-22-2017, 04:03 PM	#9
idiit Banned Join Date: Jun 2010 Posts: 3,095	Seven deaths in Kiwi synthetic cannabis epidemic this month 21 Jul, 2017 3:11pm https://www.nzherald.co.nz/nz/news/ar...ectid=11893530
	Quote

07-24-2017, 08:15 PM	#10
Betterhaff Senior Member Join Date: Jun 2013 Posts: 2,568	^ ^ That’s a different thing…probably of the likes of “Spice” or “K2”. Still a shame people have died using that stuff, if weed where legal there would be no need for it.
	Quote