NIDA: Cannabis Kills Cancer Cells - Page 2 - Medical Cannabis News - International Cannagraphic Magazine Forums

Betterhaff · 04-08-2015, 05:01 PM

I believe this is the abstract, haven’t found a way to get the full paper without paying.

https://mct.aacrjournals.org/content/...-0402.abstract

guam_bomb80 · 04-08-2015, 05:05 PM

Quote:

Originally Posted by stihgnobevoli

that's not what we're looking for. we're looking for an article about marijuana reducing tumors. you're never gonna find it on the NIDA page. nida is the wing of the govt that says drugs are dangerous and alcohol and tobacco are good for a healthy diet.

Here is a copy and paste from the link I provided. Stating what the op was saying about reducing the size of tumors. If you want more detailed info about it, you're right, the govt. probably won't give out much more than this at the moment. At least it's a start!

For instance, recent animal studies have shown that marijuana extracts may help kill certain cancer cells and reduce the size of others. Evidence from one cell culture study suggests that purified extracts from whole-plant marijuana can slow the growth of cancer cells from one of the most serious types of brain tumors. Research in mice showed that treatment with purified extracts of THC and CBD, when used with radiation, increased the cancer-killing effects of the radiation (Scott, 2014).

stihgnobevoli · 04-08-2015, 11:10 PM

dunno what happened, i clicked the link again and it points to a different page now. before it was pointing to some propaganda page about the dangers of marijuana.

dracenstein · 04-10-2015, 11:46 PM

This has been known since the early seventies.....

“Antineoplastic activity of cannabinoids,” an article in a 1975 Journal of the National Cancer Institute — and this writer obtained a copy at the UC medical school library in Davis and faxed it to Madrid.

The summary of the Virginia study begins, “Lewis lung adenocarcinoma growth was retarded by the oral administration of tetrahydrocannabinol (THC) and cannabinol (CBN)” — two types of cannabinoids, a family of active components in marijuana. “Mice treated for 20 consecutive days with THC and CBN had reduced primary tumor size.”

The 1975 journal article doesn’t mention breast cancer tumors, which featured in the only newspaper story ever to appear about the 1974 study — in the Local section of the Washington Post on August 18, 1974. Under the headline, “Cancer Curb Is Studied,” it read in part:

“The active chemical agent in marijuana curbs the growth of three kinds of cancer in mice and may also suppress the immunity reaction that causes rejection of organ transplants, a Medical College of Virginia team has discovered.” The researchers “found that THC slowed the growth of lung cancers, breast cancers and a virus-induced leukemia in laboratory mice, and prolonged their lives by as much as 36 percent.”

From...
https://patients4medicalmarijuana.wo...wn-since-1974/

ShawnBaker · 04-11-2015, 07:04 PM

Quote:

Originally Posted by Puffin13

I found the article on a few different sites but the link back to NIDA doesnt seem to work on any of them. I really despise fake news reports so I hope this is not bogus. If it is fake, my deepest apologies to the IC Mag community!

Me too!

_____________________________
find cannabis dispensaries in Bothell Washington

vostok · 04-11-2015, 09:25 PM

NIDA: Cannabis Kills Cancer Cells

The requested page
"/sites/default/files/df_ismarijuanamedicine_4_2015. pdf"
could not be found.

stihgnobevoli · 04-12-2015, 12:27 AM

Try searching for the pdf by name, maybe Google cached it or someone saved it before they tried to drop it down the memory hole. Everyone seems to forget the Internet is forever. and by everyone i mean people who think just because you delete a link the information is gone. not you specifically or anything.

https://dailycaller.com/wp-content/up...ine_4_2015.pdf

it's the same thing as that link a couple posts up at the nida website.

tiodrowconta198 · 10-20-2015, 06:32 PM

Quote:

Originally Posted by ShawnBaker

Me too!

More info about marijuana anti-cancer properties:
https://allweednews.com/nida-recogniz...inal-cannabis/
https://allweednews.com/the-national-...-of-marijuana/
Jah Bless ya! Stay healthy lads and gentlemen

trichrider · 10-20-2015, 07:53 PM

https://www.researchgate.net/publicat...way_in_Gliomas

Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas

Department of Biochemistry and Molecular Biology I, School of Biology, Complutense University, Madrid, Spain.
Cancer Research (Impact Factor: 9.33). 09/2004; 64(16):5617-23. DOI: 10.1158/0008-5472.CAN-03-3927
Source: PubMed

ABSTRACT
Cannabinoids inhibit tumor angiogenesis in mice, but the mechanism of their antiangiogenic action is still unknown. Because the vascular endothelial growth factor (VEGF) pathway plays a critical role in tumor angiogenesis, here we studied whether cannabinoids affect it. As a first approach, cDNA array analysis showed that cannabinoid administration to mice bearing s.c. gliomas lowered the expression of various VEGF pathway-related genes. The use of other methods (ELISA, Western blotting, and confocal microscopy) provided additional evidence that cannabinoids depressed the VEGF pathway by decreasing the production of VEGF and the activation of VEGF receptor (VEGFR)-2, the most prominent VEGF receptor, in cultured glioma cells and in mouse gliomas. Cannabinoid-induced inhibition of VEGF production and VEGFR-2 activation was abrogated both in vitro and in vivo by pharmacological blockade of ceramide biosynthesis. These changes in the VEGF pathway were paralleled by changes in tumor size. Moreover, intratumoral administration of the cannabinoid Delta9-tetrahydrocannabinol to two patients with glioblastoma multiforme (grade IV astrocytoma) decreased VEGF levels and VEGFR-2 activation in the tumors. Because blockade of the VEGF pathway constitutes one of the most promising antitumoral approaches currently available, the present findings provide a novel pharmacological target for cannabinoid-based therapies

Cancer – breast

Anandamide inhibits human breast cancer cell proliferation
https://www.pnas.org/cgi/content/abstract/95/14/8375

Inhibition of Human Breast and Prostate Cancer Cell Proliferation1
https://endo.endojournals.org/cgi/co...tract/141/1/118

Antitumor Activity of Plant Cannabinoids
https://jpet.aspetjournals.org/cgi/c...ract/318/3/1375

9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer
https://cancerres.aacrjournals.org/c...ract/66/13/6615

Cannabidiol inhibits tumour growth in leukaemia and breast cancer
https://www.cannabis-med.org/english...el.php?id=220#2

THC and prochlorperazine effective in reducing vomiting in women following breast surgery
https://www.cannabis-med.org/english...el.php?id=219#1

Cancer- colorectal

Anandamide, induces cell death in colorectal carcinoma cells
https://gut.bmj.com/cgi/content/abstract/54/12/1741

Cannabinoids and cancer: potential for colorectal cancer therapy.
https://www.medscape.com/medline/abstract/16042581

Cancer- glioma/ brain

Anti-tumor effects of cannabidiol
https://www.hempworld.com/HempPharm/...milanstudy.html

Pot’s cancer healing properties
https://www.november.org/stayinfo/br...ncerKiller.html

Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas
https://cancerres.aacrjournals.org/c...hort/64/16/5617

Inhibition of Glioma Growth in Vivo
https://cancerres.aacrjournals.org/c.../61/15/5784.pdf

Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
https://www.cannabis-med.org/studies...ow.php?s_id=193

Cannabidiol triggers caspase activation and oxidative stress in human glioma cells.
https://www.ihop-net.org/UniPub/iHOP...l?pmid=16909207

Cannabinoid receptors in human astroglial tumors
https://www.brainlife.org/abstracts/...t_j20060800.pdf

Cannabis extract makes brain tumors shrink, halts growth of blood vessels
https://www.medicalnewstoday.com/articles/12088.php

THC tested against brain tumour in pilot clinical study
https://www.cannabis-med.org/english...el.php?id=222#1

Cancer- leukemia

Cannabis-induced cytotoxicity in leukemic cell lines
https://bloodjournal.hematologylibra...ract/105/3/1214

Cannabidiol-Induced Apoptosis in Human Leukemia Cells
https://molpharm.aspetjournals.org/c...stract/70/3/897

Marijuana's Active Ingredient Kills Leukemia Cells
https://www.treatingyourself.com/vbu...read.php?t=7107

Targeting CB2 cannabinoid receptors to treat malignant lymphoblastic disease
https://bloodjournal.hematologylibra...t/100/2/627.pdf

Cannabinoids induce incomplete maturation of cultured human leukemia cells
https://www.osti.gov/energycitations...osti_id=5164483

{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells
https://mcr.aacrjournals.org/cgi/con...bstract/4/8/549

Cannabidiol inhibits tumour growth in leukaemia and breast cancer
https://www.cannabis-med.org/english...el.php?id=220#2

Cancer- lung

Antineoplastic activity of cannabinoids
https://www.ukcia.org/research/Antin...ds/default.html

Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration
https://www.unboundmedicine.com/medl...astasis_in_vivo

Smoking Cannabis Does Not Cause Cancer Of Lung or Upper Airways
https://ccrmg.org/journal/05aut/nocancer.html

No association between lung cancer and cannabis smoking in large study
https://www.cannabis-med.org/english...el.php?id=219#2

Marijuana Smoking Found Non-Carcinogenic
https://www.medpagetoday.com/Hematol...gCancer/tb/3393

CLAIM #4: MARIJUANA CAUSES LUNG DISEASE
https://www.erowid.org/plants/cannab...bis_myth4.shtml

Cancer- melanoma

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.
https://www.cannabis-med.org/studies...ow.php?s_id=180

Intractable nausea and vomiting due to gastrointestinal mucosal metastases
https://www.cannabis-med.org/studies...how.php?s_id=35

Cancer – oral

Smoking of cannabis does not increase risk for oral cancer
https://www.cannabis-med.org/english...el.php?id=175#1

Marijuana use and Risk of Oral Squamous Cell Carcinoma
https://66.218.69.11/search/cache?ei...&icp=1&.intl=us

Cancer-pancreatic

Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells
https://cancerres.aacrjournals.org/c...ract/66/13/6748

Cancer – prostrate

Inhibition of Human Breast and Prostate Cancer Cell Proliferation
https://endo.endojournals.org/cgi/co...tract/141/1/118

Cannabinoid Receptor as a Novel Target for the Treatment of Prostate Cancer
https://cancerres.aacrjournals.org/c...t/65/5/1635.pdf

Cancer – Risk

Cannabis vs Tobacco

Cannabis Smoke and Cancer: Assessing the Risk
https://www.norml.org/index.cfm?Group_ID=6891

Cannabis and tobacco smoke are not equally carcinogenic
https://www.pubmedcentral.nih.gov/ar...i?artid=1277837

Smoking Marijuana Does Not Cause Lung Cancer
https://www.mapinc.org/drugnews/v05/n1065/a03.html

Blunt Smokers Link Dependence Potential To Nicotine
https://www.medicalnewstoday.com/articles/52838.php

Premiere British Medical Journal Pronounces Marijuana Safer Than Alcohol, Tobacco
https://cannabislink.ca/medical/safer.html

Why Doesn't Smoking Marijuana Cause Cancer?
https://www.healthcentral.com/drdean/408/14275.html

Marijuana Smoking Found Non-Carcinogenic
https://www.medpagetoday.com/Hematol...gCancer/tb/3393

Cancer - Skin

Inhibition of skin tumor growth
https://www.jci.org/cgi/content/full...y=MpUgjDbqHybAU

Cannabis Reduces Skin Cancer
https://www.onlinepot.org/medical/skincancerreport.htm

Cancer – Testicular

The antiemetic efficacy of nabilone
https://www.cannabis-med.org/studies...ow.php?s_id=127

Chemotherapy for Testicular Cancer
https://www.rxmarihuana.com/shared_c...icularchemo.htm

Cancer –various/ unnamed

Derivatives of cannabis for anti-cancer treatment
https://www.eurekalert.org/pub_relea...uo-do060605.php

giddyup!

GrinStick · 10-21-2015, 05:53 PM

holy hell trichrider, thas quite a list.
it will take weeks to read those,

04-10-2015, 11:46 PM	#14
dracenstein Newbie Join Date: Apr 2015 Posts: 1	This has been known since the early seventies..... “Antineoplastic activity of cannabinoids,” an article in a 1975 Journal of the National Cancer Institute — and this writer obtained a copy at the UC medical school library in Davis and faxed it to Madrid. The summary of the Virginia study begins, “Lewis lung adenocarcinoma growth was retarded by the oral administration of tetrahydrocannabinol (THC) and cannabinol (CBN)” — two types of cannabinoids, a family of active components in marijuana. “Mice treated for 20 consecutive days with THC and CBN had reduced primary tumor size.” The 1975 journal article doesn’t mention breast cancer tumors, which featured in the only newspaper story ever to appear about the 1974 study — in the Local section of the Washington Post on August 18, 1974. Under the headline, “Cancer Curb Is Studied,” it read in part: “The active chemical agent in marijuana curbs the growth of three kinds of cancer in mice and may also suppress the immunity reaction that causes rejection of organ transplants, a Medical College of Virginia team has discovered.” The researchers “found that THC slowed the growth of lung cancers, breast cancers and a virus-induced leukemia in laboratory mice, and prolonged their lives by as much as 36 percent.” From... https://patients4medicalmarijuana.wo...wn-since-1974/
	Quote 2 members found this post helpful.

10-20-2015, 07:53 PM	#19
trichrider THEORETICAL Join Date: Apr 2010 Location: between CB1 and the singularity. Posts: 7,046	https://www.researchgate.net/publicat...way_in_Gliomas Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas Department of Biochemistry and Molecular Biology I, School of Biology, Complutense University, Madrid, Spain. Cancer Research (Impact Factor: 9.33). 09/2004; 64(16):5617-23. DOI: 10.1158/0008-5472.CAN-03-3927 Source: PubMed ABSTRACT Cannabinoids inhibit tumor angiogenesis in mice, but the mechanism of their antiangiogenic action is still unknown. Because the vascular endothelial growth factor (VEGF) pathway plays a critical role in tumor angiogenesis, here we studied whether cannabinoids affect it. As a first approach, cDNA array analysis showed that cannabinoid administration to mice bearing s.c. gliomas lowered the expression of various VEGF pathway-related genes. The use of other methods (ELISA, Western blotting, and confocal microscopy) provided additional evidence that cannabinoids depressed the VEGF pathway by decreasing the production of VEGF and the activation of VEGF receptor (VEGFR)-2, the most prominent VEGF receptor, in cultured glioma cells and in mouse gliomas. Cannabinoid-induced inhibition of VEGF production and VEGFR-2 activation was abrogated both in vitro and in vivo by pharmacological blockade of ceramide biosynthesis. These changes in the VEGF pathway were paralleled by changes in tumor size. Moreover, intratumoral administration of the cannabinoid Delta9-tetrahydrocannabinol to two patients with glioblastoma multiforme (grade IV astrocytoma) decreased VEGF levels and VEGFR-2 activation in the tumors. Because blockade of the VEGF pathway constitutes one of the most promising antitumoral approaches currently available, the present findings provide a novel pharmacological target for cannabinoid-based therapies Cancer – breast Anandamide inhibits human breast cancer cell proliferation https://www.pnas.org/cgi/content/abstract/95/14/8375 Inhibition of Human Breast and Prostate Cancer Cell Proliferation1 https://endo.endojournals.org/cgi/co...tract/141/1/118 Antitumor Activity of Plant Cannabinoids https://jpet.aspetjournals.org/cgi/c...ract/318/3/1375 9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer https://cancerres.aacrjournals.org/c...ract/66/13/6615 Cannabidiol inhibits tumour growth in leukaemia and breast cancer https://www.cannabis-med.org/english...el.php?id=220#2 THC and prochlorperazine effective in reducing vomiting in women following breast surgery https://www.cannabis-med.org/english...el.php?id=219#1 Cancer- colorectal Anandamide, induces cell death in colorectal carcinoma cells https://gut.bmj.com/cgi/content/abstract/54/12/1741 Cannabinoids and cancer: potential for colorectal cancer therapy. https://www.medscape.com/medline/abstract/16042581 Cancer- glioma/ brain Anti-tumor effects of cannabidiol https://www.hempworld.com/HempPharm/...milanstudy.html Pot’s cancer healing properties https://www.november.org/stayinfo/br...ncerKiller.html Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas https://cancerres.aacrjournals.org/c...hort/64/16/5617 Inhibition of Glioma Growth in Vivo https://cancerres.aacrjournals.org/c.../61/15/5784.pdf Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. https://www.cannabis-med.org/studies...ow.php?s_id=193 Cannabidiol triggers caspase activation and oxidative stress in human glioma cells. https://www.ihop-net.org/UniPub/iHOP...l?pmid=16909207 Cannabinoid receptors in human astroglial tumors https://www.brainlife.org/abstracts/...t_j20060800.pdf Cannabis extract makes brain tumors shrink, halts growth of blood vessels https://www.medicalnewstoday.com/articles/12088.php THC tested against brain tumour in pilot clinical study https://www.cannabis-med.org/english...el.php?id=222#1 Cancer- leukemia Cannabis-induced cytotoxicity in leukemic cell lines https://bloodjournal.hematologylibra...ract/105/3/1214 Cannabidiol-Induced Apoptosis in Human Leukemia Cells https://molpharm.aspetjournals.org/c...stract/70/3/897 Marijuana's Active Ingredient Kills Leukemia Cells https://www.treatingyourself.com/vbu...read.php?t=7107 Targeting CB2 cannabinoid receptors to treat malignant lymphoblastic disease https://bloodjournal.hematologylibra...t/100/2/627.pdf Cannabinoids induce incomplete maturation of cultured human leukemia cells https://www.osti.gov/energycitations...osti_id=5164483 {Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells https://mcr.aacrjournals.org/cgi/con...bstract/4/8/549 Cannabidiol inhibits tumour growth in leukaemia and breast cancer https://www.cannabis-med.org/english...el.php?id=220#2 Cancer- lung Antineoplastic activity of cannabinoids https://www.ukcia.org/research/Antin...ds/default.html Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration https://www.unboundmedicine.com/medl...astasis_in_vivo Smoking Cannabis Does Not Cause Cancer Of Lung or Upper Airways https://ccrmg.org/journal/05aut/nocancer.html No association between lung cancer and cannabis smoking in large study https://www.cannabis-med.org/english...el.php?id=219#2 Marijuana Smoking Found Non-Carcinogenic https://www.medpagetoday.com/Hematol...gCancer/tb/3393 CLAIM #4: MARIJUANA CAUSES LUNG DISEASE https://www.erowid.org/plants/cannab...bis_myth4.shtml Cancer- melanoma Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases. https://www.cannabis-med.org/studies...ow.php?s_id=180 Intractable nausea and vomiting due to gastrointestinal mucosal metastases https://www.cannabis-med.org/studies...how.php?s_id=35 Cancer – oral Smoking of cannabis does not increase risk for oral cancer https://www.cannabis-med.org/english...el.php?id=175#1 Marijuana use and Risk of Oral Squamous Cell Carcinoma https://66.218.69.11/search/cache?ei...&icp=1&.intl=us Cancer-pancreatic Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells https://cancerres.aacrjournals.org/c...ract/66/13/6748 Cancer – prostrate Inhibition of Human Breast and Prostate Cancer Cell Proliferation https://endo.endojournals.org/cgi/co...tract/141/1/118 Cannabinoid Receptor as a Novel Target for the Treatment of Prostate Cancer https://cancerres.aacrjournals.org/c...t/65/5/1635.pdf Cancer – Risk Cannabis vs Tobacco Cannabis Smoke and Cancer: Assessing the Risk https://www.norml.org/index.cfm?Group_ID=6891 Cannabis and tobacco smoke are not equally carcinogenic https://www.pubmedcentral.nih.gov/ar...i?artid=1277837 Smoking Marijuana Does Not Cause Lung Cancer https://www.mapinc.org/drugnews/v05/n1065/a03.html Blunt Smokers Link Dependence Potential To Nicotine https://www.medicalnewstoday.com/articles/52838.php Premiere British Medical Journal Pronounces Marijuana Safer Than Alcohol, Tobacco https://cannabislink.ca/medical/safer.html Why Doesn't Smoking Marijuana Cause Cancer? https://www.healthcentral.com/drdean/408/14275.html Marijuana Smoking Found Non-Carcinogenic https://www.medpagetoday.com/Hematol...gCancer/tb/3393 Cancer - Skin Inhibition of skin tumor growth https://www.jci.org/cgi/content/full...y=MpUgjDbqHybAU Cannabis Reduces Skin Cancer https://www.onlinepot.org/medical/skincancerreport.htm Cancer – Testicular The antiemetic efficacy of nabilone https://www.cannabis-med.org/studies...ow.php?s_id=127 Chemotherapy for Testicular Cancer https://www.rxmarihuana.com/shared_c...icularchemo.htm Cancer –various/ unnamed Derivatives of cannabis for anti-cancer treatment https://www.eurekalert.org/pub_relea...uo-do060605.php giddyup! __________________ "I'm not always a dick...but when I am, I drink cheap beer".
	Quote 2 members found this post helpful.

10-21-2015, 05:53 PM	#20
GrinStick Indignados! Join Date: May 2010 Location: between grinds Posts: 213	holy hell trichrider, thas quite a list. it will take weeks to read those, __________________ someday we will all get along!
	Quote

04-08-2015, 05:01 PM	#11
Betterhaff Senior Member Join Date: Jun 2013 Posts: 2,568	I believe this is the abstract, haven’t found a way to get the full paper without paying. https://mct.aacrjournals.org/content/...-0402.abstract
	Quote

04-08-2015, 11:10 PM	#13
stihgnobevoli Banned Join Date: Feb 2007 Posts: 5,734	dunno what happened, i clicked the link again and it points to a different page now. before it was pointing to some propaganda page about the dangers of marijuana.
	Quote

04-11-2015, 09:25 PM	#16
vostok Banned Join Date: Jan 2009 Location: Far East Posts: 1,513	NIDA: Cannabis Kills Cancer Cells The requested page "/sites/default/files/df_ismarijuanamedicine_4_2015. pdf" could not be found.
	Quote

04-12-2015, 12:27 AM	#17
stihgnobevoli Banned Join Date: Feb 2007 Posts: 5,734	Try searching for the pdf by name, maybe Google cached it or someone saved it before they tried to drop it down the memory hole. Everyone seems to forget the Internet is forever. and by everyone i mean people who think just because you delete a link the information is gone. not you specifically or anything. https://dailycaller.com/wp-content/up...ine_4_2015.pdf it's the same thing as that link a couple posts up at the nida website.
	Quote