[LostTribe]

Ok back to the subject at hand.

Any Cancer Treatment patients in the house that are using concentrates? Methods? Outlook?

You are all in our thoughts, Jah Blessed.

LT

[LostTribe]

Somebody was on here discussing his colon cancer treatments this week hope he keeps strong and fights through it!

[LostTribe]

For the suppositories what are the recommended dosages? Are you guys infusing with coco oil or just straight concentrates?

[LostTribe]

Originally Posted by Gray Wolf

Ummm, 200 mg of cannabis absolute in a coco butter suppository certainly demonstrated THC effects when I personally tested it and the cancer patients we've made them for report effects as well.

Hee, hee, hee, wait till I tell you where we all stuck them!

So is the 200mg of absolute combined with coco oil what you would recommend for most cancer patients?

[Mednugs]

If you are using suppositories I whould recommend olive oil over coco. It blends evenly and doesn't separate. And I would be afraid to go over 1:1

[Gray Wolf]

Originally Posted by LostTribe

So is the 200mg of absolute combined with coco oil what you would recommend for most cancer patients?

Coco butter. It is stiff enough to insert, where coconut oil is not.

We worked our cancer patients up to 300 mg doses. I only tested the 200 mg.

[Gray Wolf]

Originally Posted by Mednugs

If you are using suppositories I whould recommend olive oil over coco. It blends evenly and doesn't separate. And I would be afraid to go over 1:1

Ummmm, how easy is it to insert? Maybe a little like shooting pool with a cotton rope for a cue?

[live resin]

Originally Posted by G.O. Joe

It's an established scientific fact, whether it's true or not. The hemisuccinate ester is the usual suppository form of THC.

Does conversion to the ester make it more water soluble?

Would this same prodrug work orally or is it completely different mechanisms of absorption and metabolization?

[aridbud]

Currently have a friend with pancreatic cancer w/ metastasis into liver, 2nd round of chemo. Made some oil using ethanol/rice cooker and 20 cc syringe. He felt it was too 'druggy' (his term) not being a cannabis user. We experimented with dose, but he didn't like the sensation orally.

Then, I made suppositories from the remaining oil (size 1#). He's taking 3x a day, larger dose at night (00#). Reports less pain, a bit more energy, ability to eat after chemo.

Made another batch finely ground herb heated in coconut oil, then cooled before filling capsules. He seems to tolerate that better, again, 3x a day (size 1# gel capsule) and 00# at night. Cannot accurately measure g/ml and mg, but ratios for ground herb into oil 3:1.5, similar to a paste.

Any added suggestions would be welcome.

[G.O. Joe]

Originally Posted by live resin

Does conversion to the ester make it more water soluble?

Would this same prodrug work orally or is it completely different mechanisms of absorption and metabolization?

I assume it's easily hydrolyzed regardless - it can be injected as well - so measuring solubility could be a problem.