Register ICMag Forum Menu Features Mark Forums Read
You are viewing our:
in:
Forums > Talk About It! > Medicinal Cannabis Forum > Learn how Cannabinoids kill cancer! Part 1: Reducing VEGF (Show people this!)

Thread Title Search
Click for Weed Seed Shop
Post Reply
Learn how Cannabinoids kill cancer! Part 1: Reducing VEGF (Show people this!) Thread Tools
Old 04-22-2012, 01:25 PM #11
Toes.
Guest

Posts: n/a
Thank you for this informative thread Bi0hazard
Mad Respect.
Quote


Old 04-22-2012, 02:11 PM #12
Hoover_lungz
Guest

Posts: n/a
Cannabis has been used as medicine through out History and now scientist have proven it to be facts.


On this planet our creator has given us many plants and herbs that can cure any disease and ilness, its upto us to find them and use them in the correct ways

Cannabis is one of the best meds with zero side effects exept heavy munchy attacks and being extremly peacfull
Quote


1 members found this post helpful.
Old 04-22-2012, 02:49 PM #13
TLoft13
Member

TLoft13's Avatar

Join Date: May 2009
Posts: 873
TLoft13 is a jewel in the roughTLoft13 is a jewel in the roughTLoft13 is a jewel in the roughTLoft13 is a jewel in the roughTLoft13 is a jewel in the roughTLoft13 is a jewel in the roughTLoft13 is a jewel in the rough
Quote:
Originally Posted by Hash Zeppelin View Post
I smoked pure high quality bho at a heavy rate after i got burns on my face, and scars that were supposed to be there for a year are not there at all. second degree burns. no scars. the doctor is shocked!
Congratulations!
May i ask what happened? Accident while making oil?
__________________
1200W seed SOG
1200W tent SCROG; FMS Superskunk, Easy Sativa, KC Brains KC33(fem.)
Current setup: 1800W Gavita Triplestar, 12/12 from seed SOG, Nirvana AK48

TLoft13 is offline Quote


Old 04-22-2012, 03:15 PM #14
Hash Zeppelin
Ski Bum Rodeo Clown

Hash Zeppelin's Avatar

Join Date: Sep 2008
Location: The Misty Mountains
Posts: 9,307
Hash Zeppelin has a reputation beyond reputeHash Zeppelin has a reputation beyond reputeHash Zeppelin has a reputation beyond reputeHash Zeppelin has a reputation beyond reputeHash Zeppelin has a reputation beyond reputeHash Zeppelin has a reputation beyond reputeHash Zeppelin has a reputation beyond reputeHash Zeppelin has a reputation beyond reputeHash Zeppelin has a reputation beyond reputeHash Zeppelin has a reputation beyond reputeHash Zeppelin has a reputation beyond repute
Quote:
Originally Posted by TLoft13 View Post
Congratulations!
May i ask what happened? Accident while making oil?
It was a freak grilling accident. I was turning the steak and there was some fat on fire in the bottom of the grill. The wind blew really hard at the same time a coal popped. It was the cole covered in burning fat.

It landed on my shoulder length hair and burned my hair, face, and neck.

I was wearing a fire resistant hat and windbreaker from REI. all there gear is fire resistant I think. the burns stopped when the fire hit the edge of the hat and jacket, and I was able to throw it off.

this all happened in under 3 seconds.

I was by myself. if it was not for the jacket and hat stopping the fire my whole head would have went up and I would be dead now.
__________________
Grow thread.
https://www.icmag.com/ic/showthread....04#post7552204

Quote:
"I know no safe depositary of the ultimate powers of the society but the people themselves; and if we think them not enlightened enough to exercise their control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education. This is the true corrective of abuses of constitutional power." -Thomas Jefferson
Quote:
"Who are we? We find that we live on an insignificant planet of a humdrum star lost in a galaxy tucked away in some forgotten corner of a universe in which there are far more galaxies than people." -Carl Sagan
Quote:
"When a government is dependent upon bankers for money, they and not the leaders of the government control the situation, since the hand that gives is above the hand that takes. Money has no motherland; financiers are without patriotism and without decency; their sole object is gain."
-Napoleon Bonaparte
Hash Zeppelin is offline Quote


1 members found this post helpful.
Old 04-22-2012, 08:45 PM #15
Bi0hazard
Senior Member

Bi0hazard's Avatar

Join Date: Apr 2009
Location: Legally Compliant
Posts: 1,399
Bi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to all
Glioma Cancer Article: Cannabinoids inhibit glioma cell invasion in brain cancer studies (2010)
Full Write up and Primary Article @ http://www.examiner.com/article/cann...cancer-studies

Researchers in Spain publish juicy studies such as this one: Cannabinoids, the active components of Cannabis sativa L. and their derivatives, inhibit tumor growth in laboratory animals by inducing apoptosis of tumor cells and impairing tumor angiogenesis.
Bi0hazard is offline Quote


Old 04-22-2012, 08:47 PM #16
Bi0hazard
Senior Member

Bi0hazard's Avatar

Join Date: Apr 2009
Location: Legally Compliant
Posts: 1,399
Bi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to all
Leukaemia and Breast Cancer Article: Cannabidiol inhibits tumour growth in leukaemia and breast cancer in animal studies (2006)

Italian researchers investigated the anti-tumour effects of five natural cannabinoids of the cannabis plant (cannabidiol, cannabigerol, cannabichromene, cannabidiol-acid and THC-acid) in breast cancer. Cannabidiol (CBD) was the most potent cannabinoid in inhibiting the growth of human breast cancer cells that had been injected under the skin of mice. CBD also reduced lung metastases deriving from human breast cancer cells that had been injected into the paws of the animals.

Researchers found that the anti-tumour effects of CBD were caused by induction of apoptosis (programmed cell death). They concluded that their data "support the further testing of cannabidiol and cannabidiol-rich extracts for the potential treatment of cancer."

These observations are supported by investigations of US scientists who found out that exposure of leukaemia cells to CBD led to a reduction in cell viability and induction of apoptosis. In living animals CBD caused a reduction in number of leukaemia cells. The scientists noted that CBD "may be a novel and highly selective treatment for leukemia."

(Sources: Ligresti A, Schiano Moriello A, Starowicz K, Matias I, Pisanti S, De Petrocellis L, Laezza C, Portella G, Bifulco M, Di Marzo V. Anti-tumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. J Pharmacol Exp Ther. 2006 May 25; [electronic publication ahead of print]; McKallip RJ, Jia W, Schlomer J, Warren JW, Nagarkatti PS, Nagarkatti M. Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression. Mol Pharmacol. 2006 Jun 5; [electronic publication ahead of print])
Bi0hazard is offline Quote


1 members found this post helpful.
Old 04-22-2012, 08:53 PM #17
Bi0hazard
Senior Member

Bi0hazard's Avatar

Join Date: Apr 2009
Location: Legally Compliant
Posts: 1,399
Bi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to all
Melanoma Cancer Article: Cannabinoid receptor-1 modulation induces apoptosis of human melanoma cells (2008) Apoptosis = Cell Death (in this case of Cancer Cells only)

Full Article @ www.fasebj.org/content/20/14/2633.full.pdf

ABSTRACT Melanoma causes the greatest number of skin cancer-related deaths worldwide. Despite intensive research, prevention and early detection are the only effective measures against melanoma, so new therapeutic strategies are necessary for the management of this devastating disease. Here, we evaluated the efficacy of cannabinoid receptor agonists, a new family of potential antitumoral compounds, at skin melanoma. Human melanomas and melanoma cell lines express CB1 and CB2 cannabinoid receptors. Activation of these receptors decreased growth, proliferation, angiogenesis and metastasis, and increased apoptosis, of melanomas in mice. Cannabinoid antimelanoma activity was independent of the immune status of the animal, could be achieved without overt psychoactive effects and was selective for melanoma cells vs. normal melanocytes. Cannabinoid antiproliferative action on melanoma cells was due, at least in part, to cell cycle arrest at the G1-S transition via inhibition of the prosurvival protein Akt and hypophosphorylation of the pRb retinoblastoma protein tumor suppressor. These findings may contribute to the design of new chemotherapeutic strategies for the management of melanoma.—
Bi0hazard is offline Quote


1 members found this post helpful.
Old 04-22-2012, 09:03 PM #18
Bi0hazard
Senior Member

Bi0hazard's Avatar

Join Date: Apr 2009
Location: Legally Compliant
Posts: 1,399
Bi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to all
Lymphoma Cancer Article: Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma. (2005)

Abstract: http://journals1.scholarsportal.info...lmgicdimcl.xml

We have earlier reported overexpression of the central and peripheral cannabinoid receptors CB1 and CB2 in mantle cell lymphoma (MCL), a B cell non-Hodgkin lymphoma. In this study, treatment with cannabinoid receptor ligands caused a decrease in viability of MCL cells, while control cells lacking CB1 were not affected. Interestingly, equipotent doses of the CB1 antagonist SR141716A and the CB1/CB2 agonist anandamide inflicted additive negative effects on viability. Moreover, treatment with the CB1/CB2 agonist Win-55,212-2 caused a decrease in long-term growth of MCL cells in culture. Induction of apoptosis, as measured by FACS/Annexin V-FITC, contributed to the growth suppressive effect of Win-55,212-2. Our data suggest that cannabinoid receptors may be considered as potential therapeutic targets in MCL.
Bi0hazard is offline Quote


1 members found this post helpful.
Old 04-22-2012, 09:05 PM #19
Bi0hazard
Senior Member

Bi0hazard's Avatar

Join Date: Apr 2009
Location: Legally Compliant
Posts: 1,399
Bi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to all
Pancreatic Cancer Article: Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress–Related Genes (2006) Apoptosis = Cell Death (in this case of Cancer Cells only)

Full Article: http://cancerres.aacrjournals.org/co...6/13/6748.full

Abstract: Pancreatic adenocarcinomas are among the most malignant forms of cancer and, therefore, it is of especial interest to set new strategies aimed at improving the prognostic of this deadly disease. The present study was undertaken to investigate the action of cannabinoids, a new family of potential antitumoral agents, in pancreatic cancer. We show that cannabinoid receptors are expressed in human pancreatic tumor cell lines and tumor biopsies at much higher levels than in normal pancreatic tissue. Studies conducted with MiaPaCa2 and Panc1 cell lines showed that cannabinoid administration (a) induced apoptosis, (b) increased ceramide levels, and (c) up-regulated mRNA levels of the stress protein p8. These effects were prevented by blockade of the CB2 cannabinoid receptor or by pharmacologic inhibition of ceramide synthesis de novo. Knockdown experiments using selective small interfering RNAs showed the involvement of p8 via its downstream endoplasmic reticulum stress–related targets activating transcription factor 4 (ATF-4) and TRB3 in Δ9-tetrahydrocannabinol–induced apoptosis. Cannabinoids also reduced the growth of tumor cells in two animal models of pancreatic cancer. In addition, cannabinoid treatment inhibited the spreading of pancreatic tumor cells. Moreover, cannabinoid administration selectively increased apoptosis and TRB3 expression in pancreatic tumor cells but not in normal tissue. In conclusion, results presented here show that cannabinoids lead to apoptosis of pancreatic tumor cells via a CB2 receptor and de novo synthesized ceramide-dependent up-regulation of p8 and the endoplasmic reticulum stress–related genes ATF-4 and TRB3. These findings may contribute to set the basis for a new therapeutic approach for the treatment of pancreatic cancer.
Bi0hazard is offline Quote


2 members found this post helpful.
Old 04-29-2012, 09:04 PM #20
Bi0hazard
Senior Member

Bi0hazard's Avatar

Join Date: Apr 2009
Location: Legally Compliant
Posts: 1,399
Bi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to allBi0hazard is a name known to all
Quote:
Originally Posted by Hash Zeppelin View Post
I smoked pure high quality bho at a heavy rate after i got burns on my face, and scars that were supposed to be there for a year are not there at all. second degree burns. no scars. the doctor is shocked!
I wonder what the CDN levels were on your BHO..

“CBN” = cannabinol – Formed when CBNA is heated (or exposed to UV light). Sedative, antibacterial(MRSA), Treats Burns, psoriasis, breast cancer
Bi0hazard is offline Quote


2 members found this post helpful.

Post Reply

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


All times are GMT +2. The time now is 07:45 AM.


Click for great deals at Seedbay


This site is for educational and entertainment purposes only.
You must be of legal age to view ICmag and participate here.
All postings are the responsibility of their authors.
Powered by: vBulletin Copyright ©2000 - 2016, Jelsoft Enterprises Ltd.