Again, for those who are interested in making edibles that use the potency available as efficiently, and as wisely as possible, just google my user name.. oil matters
Cannabis glandular material is notoriously difficult for the body to absorb, even when active, even when it is in the form of a warm tacky concentrate. Even in small enough form, the chemicals bounce off our cellular walls when they are not held in the form of a bioavailable solution... fat, helps our body absorb cannabis glandular material, and certain fats help more than others.
This is why even eating a fatty meal a few hours beforehand can slightly aid absorption, it lubes up cell walls and prepares them for sliding cannabinoids through. But by eating glandular material and sugar alone, you are missing out on multiple stronger doses
, to achieve the desired effect for one single dose.
We use the same techniques used by the pharmaceutical industry
to promote the absorption of certain resistant chemicals, it's sometimes called liposomal encapsulation (or LET), it is when at a micro level a chemical or chemical-containing solute has not only
been broken down into small enough particles to be capable of passing through cellular walls, but it is when a solution is formed in such a way that the solvent (ie oil; readily absorbed by the body) forms a persistent coat
around the miniscule particles of solute.
It is said that the rate of delivery provided by liposomally treated chemicals, taken orally, is almost comparable to intravenous delivery
Rather than the lesser
alternative of relying on the cell walls being oily, or oily enough, when the particles themselves are coated and individually 'lubed up', they pass through as easily, as though they were made of oil themselves.
We use the 'edible solvents' we do, not just because they break down or extract our material, which is certainly important, but because they facilitate the absorption of that material.
The oil source you choose, even dictates where in your body the potency is absorbed...
choose the wrong oil, or skip out all together, and you miss out on much of the conversion from D9THC, to the more powerful 11-OH-THC, that takes place in the liver.
Long-chain triglyceride chaining oils are primarily absorbed lymphatically, and bypass the liver. This can be good for those with certain liver/metabolism ailments, or patients who can not eat in the morning before medicating (as a too-hungry liver can over metabolize cannabinoids.. a long-chain canna capsule before breakfast will peak hunger, and a medium-chain canna capsule after breakfast will provide much more relief, from much less material).
Medium-chain triglyceride containing oils however are absorbed much more readily, and passively without the aid of bile-salts, for delivery through the portal vein and liver where the potentiating conversion takes place! Nine out of ten patients, and most recreational users, are looking for the effects provided by cannabis when its potency is carried by and delivered in a MCT oil.
Again, to each their own, and as I've said before how you feel about your meds is often very important.
Placebo effect aside though, actually absorbing a greater ratio of your meds helps most of all! I've worked with and helped the most stubborn and elderly patients who were for years, stuck fast on the old and outdated methods used since the 60's and earlier, they've since opened their eyes, and have found that by putting in the time and effort to make their edibles as well as possible (or by instructing their caregivers to do so), that they now have several times
the meds from, the same amount of material they are allotted or can afford each month.
So just google 'BadKittySmiles' for a more comprehensive recipe list and series of tutorials, which are both dispensary and Granny Storm Crow
approved, and have helped hundreds of thousands of patients
over the last decade or so absorb the most potency from both their concentrates and flowers.