[GanjaPharma]

saw the title of the thread, and thought you were LOOKING for a way to absorb THC transdermaly. then i read that you are in the terrible position of having drug tests while cultivating ganja. dont worry about the shit on your skin.

now for those of you that DO want to get THC in through your skin for muscle relief or arthritis etc. the only thing i know of that works well is DMSO mixed with hash/hash oil.

[TyChe]

OKAY. The chemical that allows substances to pass from one origin to another is DMSO. You find it, I just told you what it is. Shouldnt cost to much. sorry just the only way i can explain it. Read before trying.....On your self. Just give it to someone you dont know. And sit back, watch the show.

[Phaeton]

All the trimmers in my room have a finger bowl. Dip the fingers in the bowl (and the scissors) and trim away. Keep dipping the fingers before they get sticky. This makes the trimming go SO much easier, nothing sticks to the fingers, nothing sticks to the scissors.
Grab a bud with thumb and forefinger, pull it away from the stem, trim the inside leaf, release the bud and it all goes back in place, no clumps on the finger and thumb.
Slide the scissor tips in along the bud to the center, clip the leaf and slide back out with all the budhairs undisturbed.
A few hours of this and the hands are still smooth, scissors are only mildly tacky and the finger bowl is body temp and very brown. Mostly tricombs and a few tiny hairs, the big stuff doesn't stick enough when wet.

Keeping the hands wet repels the oils completely, I suspect just having the surface of the hands dry would not be enough to allow oil through the wet capillary layer to where fats might be found. Never got me high.

[Granger2]

I don't know about about trimming raw marijuana. I watched a video with this lady in her 60's and a younger guy making cannabis butter, and cannabis olive oil. They were cooking it down. She said it was very important to wear gloves or you will get higher than you ever wanted to be. That's with cooked [decarboxilated] cannabis. -granger

[Granger2]

I was talking about skin absorption. -granger

[exploziv]

Got high while trimming, got high while playing with bubblehash (pressing by hand), and by rubbing bho on my hands too. And I also got high by ingesting non decarboxylated green material.. so my experiences were different than yours.

[bill cooper]

I hand press my bubble hash every crop and i have never got high from it ,are you sure it wasn't the joint that you were smoking while pressing it that got you high

[exploziv]

If that's a fking placebo, then it's so real I could swear on it. I am really convinced I get some effect from raw material, especially when ingested. I get mad high when I put some leaves in my smoothies. It's not even same high as when smoking, it's more on the chill and calm side, with lightheadness and a milder cerebral high than smoking. It's about the same effect I get from cannabis tea, but stronger. When I put it on my skin the area heats up, or feels like that.. it even tingles when it's concentrated material.
Maybe it's not the thc that does that, but i'm sure some components are active and can render effects/
(sorry for my spelling i''m really high and i can barely see leters on my screen.)

[Scottish Research]

I don't think placebos work that way. Maybe I'm wrong, but it is amazing how the power of the mind and belief in a treatment or medicine can make a person better even if it is just a sugar pill that they ingested.

[dank.frank]

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689518/

Human Cannabinoid Pharmacokinetics

2.1.5. Transcutaneous

"Another route of cannabinoid exposure that avoids first-pass metabolism and improves THC bioavailability is topical administration [43]. Cannabinoids are highly hydrophobic, making transport across the aqueous layer of the skin the rate-limiting step in the diffusion process [44][45]. In vitro diffusion studies may underestimate in vivo transdermal flux [43]. After application of a dermal patch, mean steady-state plasma concentration of Δ8-THC was 4.4 ng/ml within 1.4 h, and was maintained for at least 48 h. Permeabilities of CBD and CBN were found to be 10-fold higher than for Δ8-THC. In vivo studies of transdermal drug delivery in guinea pigs noted the presence of significant amounts of plasma metabolites after topical application of THC [46]. Additional research is planned with combinations of cannabinoids in EtOH to increase drug absorption.

Transdermal delivery of cannabinoids is hoped to reduce negative side effects seen with inhalation dosing [47]. Transdermal delivery also bypasses first-pass metabolism of cannabinoids. These properties could improve the utility of transdermal cannabinoid medications. Applying a transdermal patch several hours before chemotherapy, and wearing it for several days, would be a convenient means for treating associated nausea and vomiting. Also, wearing a patch for a week to stimulate appetite could be a good alternative to twice a day oral dosing of dronabinol.

The drug-abuse potential of cannabinoid transdermal patches is expected to be low because of slow delivery of THC to the brain. However, extraction of cannabinoids from the patch for administration by a more-rapid method has not been evaluated. Diversion of fentanyl patches by drug abusers for use in such a manner has been a significant problem."



dank.Frank