Very interesting: "Darwin Dynasty Cursed By Inbreeding" - Page 3 - Hobbies and Interests - International Cannagraphic Magazine Forums

Dropped Cat · 07-13-2017, 05:18 AM

Google this:

"Estimating the Inbreeding Depression on Cognitive Behavior: A Population Based Study of Child Cohort"

The top result is the page of the study.

**Gypsy Nirvana** · 07-13-2017, 05:55 AM

Yes, that looks like a very thorough study concerning inbreeding.

Here is just a bit of it:

Discussion

Parental consanguinity leads to inbreeding which often result into genetic drift, and hence may swiftly give rise to evolutionary consequence to pose the most immediate risk.

Inbreeding exposes the action of deleterious recessive alleles and reduces fitness in terms of loss of heterozygosity. The increased homozygosity (due to inbreeding) implies lower genetic variation that may lead to the expression of recessive alleles, or loss of hybrid vigor, of essential genes for the traits and thus may lead to the cause of depression (fitness decline) among inbred populations .

The harmful effects of inbreeding were first documented and quantified in detail by Charles Darwin, who carried out experiments on 57 plant species that involved self-fertilization (inbreeding) and outcrossing between unrelated groups. Darwin’s experiments supported his hypothesis that self-fertilization must be strongly disadvantageous for the progeny produced– it lowered vigor and fertility in most of his species studied.

Further, inbreeding experiments carried out in maize plant has exposed the cause of depression in growth and vigor among selfed generations . Increased frequency of polydactyly has also been reported among inbred strains of guinea pigs .

The majority of studies done on human beings support the relationship between inbreeding and the increased risk for recessive and many other complex traits.

The pioneers of human inbreeding, Schull and Neel while studying children of atomic bomb survivors in Japan after the World War II, found higher mortality, increased rate of genetic disorders, and many other health related hazards, more often among inbred children in comparison with the non-inbred group.

The relative abundance of recessive disorders among inbred communities of many Arab countries has been associated clearly with the practice of consanguinity.

*link to the full study: https://journals.plos.org/plosone/art...l.pone.0109585

07-13-2017, 05:18 AM	#21
Dropped Cat Six Gummi Bears and Some Scotch Join Date: Jan 2014 Posts: 2,615	Google this: "Estimating the Inbreeding Depression on Cognitive Behavior: A Population Based Study of Child Cohort" The top result is the page of the study. __________________ "So we're just done with phrasing, right, that's not a thing anymore?."
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07-13-2017, 05:55 AM	#22
Gypsy Nirvana Free'd P.O.W. Join Date: Jan 2004 Location: Back in Blighty! Posts: 7,065	Yes, that looks like a very thorough study concerning inbreeding. Here is just a bit of it: Discussion Parental consanguinity leads to inbreeding which often result into genetic drift, and hence may swiftly give rise to evolutionary consequence to pose the most immediate risk. Inbreeding exposes the action of deleterious recessive alleles and reduces fitness in terms of loss of heterozygosity. The increased homozygosity (due to inbreeding) implies lower genetic variation that may lead to the expression of recessive alleles, or loss of hybrid vigor, of essential genes for the traits and thus may lead to the cause of depression (fitness decline) among inbred populations . The harmful effects of inbreeding were first documented and quantified in detail by Charles Darwin, who carried out experiments on 57 plant species that involved self-fertilization (inbreeding) and outcrossing between unrelated groups. Darwin’s experiments supported his hypothesis that self-fertilization must be strongly disadvantageous for the progeny produced– it lowered vigor and fertility in most of his species studied. Further, inbreeding experiments carried out in maize plant has exposed the cause of depression in growth and vigor among selfed generations . Increased frequency of polydactyly has also been reported among inbred strains of guinea pigs . The majority of studies done on human beings support the relationship between inbreeding and the increased risk for recessive and many other complex traits. The pioneers of human inbreeding, Schull and Neel while studying children of atomic bomb survivors in Japan after the World War II, found higher mortality, increased rate of genetic disorders, and many other health related hazards, more often among inbred children in comparison with the non-inbred group. The relative abundance of recessive disorders among inbred communities of many Arab countries has been associated clearly with the practice of consanguinity. *link to the full study: https://journals.plos.org/plosone/art...l.pone.0109585 __________________ 'It can all start from a seed'
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