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Juicing, CBD, cancer

disneychildhood

New member
I'm new to this forum. I'm a Stage IV cancer patient who is two weeks into my own cannabis cancer trial . . . My goal is to take 1 gram of RSO oil a day for 60 days. I'm also juicing leaves from three strains. I've four small tumors I'm hoping will shrink on treatment or at least stablize. There are no pharmaceutical meds known to help thus I've nothing to lose.

I've been taking 1/5 gram RSO for two years but that wasn't strong enough to stop tumor growth.

Thus I'm going for a two month intensive. I'll report back after my August CT scan.

My question today has to do with the "high" effect of THC with CBD. I was hesitate to increase my dose because of how sleepy the 1/5 gram made me (it was extract oil, 80% THC 9% CBD). I bought a higher CBD strain to use in the extract to be made into oil next week. Since I've been juicing (for two weeks) I've noticed that I don't get "high" from the oil. I'd actually counted on it to help me sleep. I didn't think sleep would be a problem taking a gram a day but it has been. I feel the CBDA and THCA from the juicing is countering the THC "high" . . . Has anyone else experienced this? My own body system feels that if you gave someone stoned, juiced leaves, would that take away the "high" and "sober" someone up?

A question pulled from my own experience.

Thank you.

SDHB germline mutation, Carney-Stratakis Dyad, Pediatric-like Gist
Oregon, USA
 

dannykarey

Well-known member
Hey sorry to hear of your medical condition.

CBD is supposed negate the effects of THC..........To see if this the case maybe try taking yer dose of THC first.........Then after an hour or 2 take your CBD dose. Not sure if that possible but I remember just seeing a post the other day by Sam S where he was talking about taking a dose of pure CBD and then trying to get high and it wouldn't work.....Can't remember what thread it was in but if I find it I'll post a link.

Goodluck bro, hope the results in August are positive......Sending ya good vibes.

Danny
 

disneychildhood

New member
Thanks. I appreciate that. I just found the fact after two years of taking RSO that with juicing I no longer got the sleep benefits . . . Which is fine especially if it shrinks my tumors. I only juice once a day in the morning yet the counter effects seem to stay . . . I'm finding it fascinating. Interested to know if juicing counters any "high" . . .
 
Disney, I'm very interested to know, I live in canada and have a German shepherd with terminal bone cancer. I am trying to find a good source of cbd. Bluebird botanicals in CO has what seems like a good quality cbd product... But they won't ship to Canada.. I talked to them on the phone... They say packages are getting turned back,.. So they won't bother trying again...my god I hate the corruption in governments and law enforcement... Only If it benefits corporations and lines to pockets of dirty politicians. It's not illegal. Yet i can't get it.
 

disneychildhood

New member
I'm new to this medicine and am only in the asking questions phase . . . From my research I think in the US you can order Hemp Oil from India (God forbid we make anything in our own country, USA) that is CBD. This is not the RSO (Rick Simpson Oil) that Canada's Rick Simpson is "famous" for promoting for its cancer fighting properties. I'm juicing CBD plants and taking RSO in hopes of battling some tumors . . . I'll get back to you in late August if this is working or not. I agree with the "it is not illegal" but "how do I get it" . . . I saw the dose the US government is allowing New Jersey residents who have approved a medical marijuana bill is 2 oz a month . . . In order to make a batch of oil a patient would have to "save up" for two years . . . The cancer will have killed them by then.
 
All due respect to Rick Simpson, but he's not a scientist, a very vocal Marijane advocate and has his heart in the right place, he has helped thousands.
I'm looking at lots of studies showing that cbd in large amounts shrinks tumours... Thc for topical skin cancer seems to be effective. I know dogs are not people, but she is like a child to me, so I am very sorry if I compare situations, if you are offended by that, I'm truly sorry. But ultimately we are looking for the same thing...to Defeat cancer.
My dog is on RSO for last 2weeks she's at about 2 grains a day... But I'm starting to think the key might be high levels of cbd... Also cbd-a can be decarbed as well... I don't know which form is better.i talked to these guys at bluebird this morn... With the laws the way they are they import hemp... But make it here... I'm not advertising for them. But I think this could help you as well. Here's their page. http://www.bluebird-botanicals.com
 

disneychildhood

New member

I read this study before but I like it because the science behind targeting the ID1 with cannabis is the same science as the cancer researchers are trying for (a pharmaceutical that targets ID1) . . . The reason I fell onto this path was the pharmaceutical companies have not developed any medications for my kind of tumors . . . I'm hopeful.

One Cannabis doctor I've been in contact with is Dr. Russo. He had a second alternative that he recommended for pets if you can't find CBD . . . fortunately I can grow my own plants and "juicing" them has no "high" because the THC needs heat to be activated. Dr. Russo has heard good results from this treatment:

There are a couple of alternatives otherwise, things like Oriental mushrooms that also may limit metastases and recurrence. My favorites are these two preparations:

http://www.fungi.com/product-detail/product/host-defense-stamets-7-capsules-60ct.html
or
http://www.fungi.com/product-detail/product/host-defense-mycommunity-capsules-120ct.html

I have seen remarkable life extension or freedom from recurrence in both people and dogs that astounded their doctors.
I hope that this information helps in some small way.
Sincerely,
Ethan Russo

Ethan Russo, MD
President, International Cannabinoid Research Society (ICRS)
Website: www.icrs.co
ICRS 2014 Meeting Website: www.icrs2014.org


I've got C02 distilled "oil" for my own use . . . I get it locally . . . They can't ship. Sorry.
 
I grow and make my own up here... I'm growing critical kush from Barney's farms right now.. I got the seeds at the start if the cbd hype for a co-worker, it's only 2.1% cbd 25%thc. I'm making my own oil using isopropyl.. I have not thought to try juicing.. That would at least give me cbd-a in higher dose she could handle. What's the idiots guide to juicing? :) Thanks so much with all this new info!!! Please make sure you do post regularly, I wish you all the best in your fight!!

I also have just cracked some cbd shark shock from the cbd crew.. I'm tring to locate some hemp seeds now for high source of cbd..
I'm so glad for you guys down in the states, the law makers are finally gaining sanity!! It's hard to believe Canada has taken 2 steps back...conservative government up here is so corrupt.. It's a joke and would be funny.. If people weren't dieing as a result of them.
 

disneychildhood

New member
The joy of juicing is there is no activated THC to worry about. Thus your high THC plant can still be juiced and get the THCA (non activated enzyme). It just takes more raw material to juice . . . Also if you are juicing it doesn't matter if the seeds are male or female . . .

The states are getting better in some places regarding cannabis but it isn't wide spread.

And even the "legal" states such as Oregon there is still a fear of the Federal government coming in and arresting everyone. Not fun.
=
 
Disney, what parts of the plant are you using for juicing and what's the process you use?
Also what's the name of the strain you used for last 2 years to make RSO.. What are you using now,,, I find it a bit funny that when people say they cured something with RSO .. They never say what strain they used... I happen to think it might be important.
 

disneychildhood

New member
I have two theories about RSO . . . There is an individual in town who makes an alcohol concentrate. He takes a few drops a day and has had success. I've taken 1/5 of a gram for two years and I've had tumors grow. With oil they test for the THC properties afterwards . . . The heating process can change the THC / CBD levels. That is probably why "strain" isn't mentioned. Also RSO is made here from the "scraps/trimmings" from harvest thus isn't necessarily one strain. The oil I'm having made for me with a C02 process is "Soul Train" . . . But . . . That is a "local" strain. It is testing 20% THC and 10% CBD. Taken "RAW" the THC wouldn't be activated, thus the amount of THCA would be the question. My grower also has Harlequin which is approx. 15% CBD 10% THC. Sometimes those with oil combine two sources to try and get a 50/50 blend. To me that makes sense as a medical dose because the CBD would counter any THC "high" . . . I've read that THC has the tumor suppressor elements while CBD has other healing elements. Thus high quantities of both is the theory I'm going on. Flowed the cancer cells and reprogram to self-destruct . . . Thus I'm finding even saying the strain can vary depending on the process of distillation.

I juice the leaves of my plant. Take 8-10 leaves (include all sizes, buds have more "up" energy properties, older leaves are bigger and more "juice" . . . run through a slow grinder like used for wheat grass . . . I add carrot and apple . . . Vit C is suppose to help dissolve any "high" . . .
 
I like your blending idea.. And I'm very jealous about your medical strain Selection. Right now my CBD shark shock are about 4 inches high. A friend has some big bud that are close to harvest, so I'm going there Sunday to get some pickings for juicing. Probably not the best strain but at least it'll get the ball rolling till my shark shock are bigger. I really hope the juicing will counter the effects of the RSO, Vesta(my dog) really gets whacked when I give her the big dose in the evening.
I was talking with a friend that has been doing cancer diet research he is saying to stay away from carbs and sugars... To try and starve the cancer. I'm going to out her on a high meat and veggie diet with some vita and omega 3-6-9.
Also, I've got some DMSO coming Friday, I'm going to make a topical rub to put on top the tumour on her leg.. Any suggestions about this stuff?
Are you decarbing the soultrain CO2 extract?
 

diffusing

Active member
I like your blending idea.. And I'm very jealous about your medical strain Selection. Right now my CBD shark shock are about 4 inches high. A friend has some big bud that are close to harvest, so I'm going there Sunday to get some pickings for juicing. Probably not the best strain but at least it'll get the ball rolling till my shark shock are bigger. I really hope the juicing will counter the effects of the RSO, Vesta(my dog) really gets whacked when I give her the big dose in the evening.
I was talking with a friend that has been doing cancer diet research he is saying to stay away from carbs and sugars... To try and starve the cancer. I'm going to out her on a high meat and veggie diet with some vita and omega 3-6-9.
Also, I've got some DMSO coming Friday, I'm going to make a topical rub to put on top the tumour on her leg.. Any suggestions about this stuff?
Are you decarbing the soultrain CO2 extract?

rather than DMSO have you considered using coconut oil as a carrier? Or do you think it would be too hard for her to resist licking it off? Im not very familiar with DMSO but it appears it can cause skin irritation and some forms are pretty aggressive chemical? id do a bit more research on DMSO perhaps before trying it out I think.. maybe there are some better non chemical options out there. Personally I use cocnut oil, but it does smell pretty damn good :)

good luck!
 

disneychildhood

New member
I know nothing about DMSO. I looked it up and there are many of these concepts out there . . . DCA was one I was looking into concerning tumor growth. Coconut oil I've also heard is the good for topical . . . I haven't tried it although my brother in law was going to try it for his skin cancer.

My research on "raw" plants, ie juicing, is that there is "no high" because the THC is not activated. Thus a high THC strain wouldn't matter if you are taking the leaves. And if anyone is "harvesting" you can use all those leaves for juice.
 
The DMSO didn't work out as good as planned. Caused surface bleeding.. Se was licking it a lot, I was worried about poisoning. So I only tried 2 x. Then made a scab on the surface... I see the vet on the 5 th of August. Maybe get a new plan.

Disney, how have you been doing? I've been looking for you to update.. I know your waiting on appointment... Just thought I would drop you a note.
 

jpt again

Member
The DMSO didn't work out as good as planned. Caused surface bleeding.. Se was licking it a lot, I was worried about poisoning. So I only tried 2 x. Then made a scab on the surface... I see the vet on the 5 th of August. Maybe get a new plan.

Disney, how have you been doing? I've been looking for you to update.. I know your waiting on appointment... Just thought I would drop you a note.



Back in the '70's DMSO was touted as a cure all for joints, etc. and people were using it. I tried it back then and it is like poison. A form of it is used for fungus on toenails, as well. Most people quit it due to the bad nasty taste you have in your mouth, from it.

I'd suggest you use RSO for the sore/tumor, you can dilute it with coconut oil but, most people that are practicing with topical cures are having great luck curing skin cancers with plain RSO. They goop up the spot and then place band-aids over it. For a pet, wrap the heck out of it or put a collar to prevent the licking.

@disneychildhood; If you are taking any other medications SSRI's, those will affect your effects, and kill the high. Hope this is helpful. There is a thread by a username of GrowGoddess called: "My Experience With Rick Simpson Oil" I suggest you Google it and read, I believe you'll find a wealth of information in that thread. It is the best I've found on the internet, to date. It does not cover 'juicing' but has important info there.

There is yet another Board that many of the members use Juicing to 'manage' their disease, as you so state in the above. The thought it might kill the high is rather interesting to me, I've not read anything like that, yet! I'll be taking the RSO soon for my auto-immune disease. My plan is to take SSRI's to combat the high and get the dose in myself as quickly as possible. If the leaves if the leaves are combating the high--well, I am "in." :biggrin:

Good luck to you Both on your mission for better health for any living being's. I too, have a pet and when the day comes..I'll be using it for her--if I can get her to stop that pitiful whining when she is stoned. I just hate that pathetic noise(she is spoiled rotten too)...but then, she managed to get into edibles (someone else dropped some crumbs in her water--I hope it was accidental).

I know some that prefer edibles for sleep. With the rso..idk if you really need it.

Regardless of what the two of you do; please keep up this thread. Many start threads like this and abandon the end; making others, just as yourselves..Googling more and more. I sure hope you'll keep up this post and what you do.

http://en.wikipedia.org/wiki/Limonene

Many here are interested in RSO and healing;

Juicing has become more popular lately and there is some information 'out there' on it. The leaves may not have many or much thc; the leaves are very high in Omega's..Per Granny Storm Crows lists and posts. Even if you don't juice them she suggests drying them and then grinding it into flour and using that for baking 'treats', for the remainder of the plants 'medication' (minerals/ vits/ supplements.

Some here are practicing with 'flavinoids' and limonene with their medications; I'd google that and at the bottom I'll place an article about it; so you get the idea.
Of course, you've covered the Omega's and other vitamins/supplements and surely have your homework finished.

Another Google for you is for: Granny StormCrows list: She is an honored member at most boards that takes healing and cannabis seriously; I think I've read some of juicing in some of her posts or some posts that she has posted in. We aren't allowed to post links to other sites or I'd set one in for you, in regards to juicing.

The best resource, in regards to the compounds of our favorite medication and details of terpenes..etc. Is Greywolf, he frequents the "Concentrate" threads and generally checks in a corrects inaccurate information. Or, Google Skunk Pharma (Oregon); he is a total expert of the plant.

HEALTH NEWS
D-Limonene: Help for Digestion, Metabolism, Detoxification, Anxiety & Breast Cancer Prevention


D-Limonene, an oil nutrient called a terpene, is an amazing natural compound found in lemon and orange peels. It has potent antioxidant and anti-inflammatory properties, offers assistance for a variety of metabolic and health problems, has anti-cancer properties, and even helps with weight management.
As a health compound, it has shown a wonderful ability to help with a variety of health issues including improving indigestion, acid reflux, and sluggish bowel. It is a unique fat cleanser and helps clear cholesterol sludge including the sludge in the gall bladder that can form stones. Another aspect of cleansing assistance is that it also helps liver detoxification enzymes. Its calming properties help settle anxiety and therefore can be used as a natural sleep aid. It helps reduce appetite and improve metabolism, making it one more nutrient to assist with healthy weight management. And of great importance, it is a superior nutrient for breast cancer prevention.
All plants synthesize terpenes and they are used by the plant as a natural defense against insects and environmental stress and to repair injuries and wounds. People naturally ingest a wide variety of terpenes in the diet, which is essential for good health. For example, all carotenes are terpenes. Many of the medicinal properties of herbs and plants are based on their terpene activity. Common to terpene activity is the interaction of terpenes with NF-kappaB, the core gene signal that regulates immunity and cellular inflammation in plants and humans.
D-Limonene is a type of terpene called a monoterpene. A person consuming 1 - 2 servings of citrus per day is likely to get 15 - 40 mg of d-Limonene; if the peels are consumed in some way this level may rise to 50 - 90 mg.
Dietary supplements of d-Limonene are typically produced from the peels of oranges, with a typical dose of 1,000 mg per capsule. This natural compound is safe in high doses and offers assistance for a variety of metabolic and health problems.
Antioxidant and Anti-inflammatory Properties

Because d-Limonene has potent antioxidant and anti-inflammatory properties, it can be used by any person as part of a general health program. In this case a dose ranging from 1,000 mg to 3,000 mg per day is adequate to significantly support your natural defense systems. Many nutrients contain antioxidant and anti-inflammatory properties, thus d-Limonene is simply another member of your team. The reason to add it to your team is to support specific health issues that it improves, wherein you actually notice the improvement. Let’s review some of these important topics.
Bowel Motility & Digestive Balance of Power

Your bowels must move forward in a timely manner. Preferably you should have a bowel movement shortly after getting up and another after breakfast or lunch. To help move your bowels forward 1,000 mg of d-Limonene per day can be enough, although higher doses may be desired.
Part of sluggish bowels is often due to an overgrowth of bacteria or Candida albicans that produce toxic metabolites that slow down your colon. Remember, d-Limonene is designed by plants to kill pathogens. It has antibacterial and anti-fungal properties.
Use enough d-Limonene to notice an improvement in the flow of your bowels.
Reflux Indigestion / GERD

Reflux occurs partly because motility is not moving forward at the optimal pace, partly because contents in the stomach are irritating, and often because bile is backing up into the stomach. D-Limonene appears to help all three aspects of this issue. Human studies have found that 1,000 mg per day or even every other day has a beneficial impact on reflux within 10 doses.
I would like to point out that while acid blocking medication is typically used to suppress symptoms of indigestion, a great deal of reflux is actually caused by bile acids moving backwards into the stomach. This is typically caused by excess food consumption, wherein your liver makes extra bile and stuffs cholesterol in it as a last ditch effort to avoid being overwhelmed by too much food. This readily causes bile stagnation in the gall bladder and bile surges into the digestive tract at the wrong times, which move backwards and cause reflux.
Because d-Limonene actually dissolves the sludge buildup in the gall bladder it can help solve the problem at its source, along with not eating too often or meals that are too large.
Detoxification & Gallstones

D-Limonene activates several of the Phase I and Phase II liver detox enzymes responsible for clearing toxins. However, I believe its greatest detoxification effect is its ability to clear fat sludge all around the body. The terpenes of d-Limonene literally dissolve fat sludge. For example, turpentine is nonfood terpenes used to dissolve oil based paint. Similarly, terpenes are one of the best compounds for dissolving cholesterol. This is why they have been shown to dissolve cholesterol gallstones. This is more common in women, because estrogen helps to supersaturate the cholesterol into a stagnant condition.
D-Limonene is also active in the lymphatic system where fat-soluble sludge often builds up and causes “plumbing problems.” These include excess mucous, shoulder stiffness, and many types of headaches. Of course, a stagnant lymph system is an immune system handicap.
An overweight person tends to build up stagnant fat in all the wrong places, which needs to be cleansed and metabolized. D-Limonene offers tremendous promise in this regard. At this time no studies evaluate whether or not it can clear out stagnant fat buildup in the arteries or damaged fat accumulation in white adipose tissue (extra pounds of stubborn fat), however, theoretically it would be quite good at these cleansing activities.
Metabolism & Weight Loss

D-Limonene has a mild appetite suppressant effect, which can be used by anyone to help settle down their appetite.
In a recent animal experiment with diabetic rats, d-Limonene treatment for 45 days was found to significantly improve all major antioxidant enzymes, reducing serious health ramifications from having this metabolic problem. Other animal studies with oils rich in d-Limonene show that it reduces food intake and body weight, and can help lower blood lipids such as cholesterol. In animals fed a high fat diet d-Limonene prevented the buildup in fat that results in a fatty liver while also preventing insulin resistance.
The ability of d-Limonene to act as an antioxidant, suppress food intake, and help fat flow along in metabolism are all attributes that help to solve the type of metabolic problems an overweight person is experiencing.
Anxiety, Sleep & Mood

D-Limonene is a selective activator of the adenosine A(2A) receptor on cell membranes, which senses molecules outside the cell and in turn triggers activity within the cell. These receptors are vital for nervous system function. The lack of their activation is associated with anxiety, insomnia, and impaired dopamine transmission (addictive tendencies and lack of motivation). A lack of activation of adenosine A(2A) receptors on immune cells results in a hyperimmune response (allergic reactions).
Various doses of d-Limonene have a potent anti-anxiety effect. Even inhaling the vapors of d-Limonene can calm down nerves as well as allergic reactions.
Taking d-Limonene before bedtime will help calm nerves and promote restful sleep, yet another benefit of this multitalented nutrient.
A Novel Nutrient for Breast Cancer Prevention

The intake of d-Limonene deserves serious consideration by any woman concerned about the breast cancer issue. There is almost three decades of animal research, along with some human cancer data. The mechanism of benefit is not limited to breast cancer. The basic nutritional value of d-Limonene and its lack of toxicity, combined with its powerful modes of operation, make it a novel nutritional tool with a great deal of upside potential. It should be considered as part of a healthy diet, exercise, and lifestyle program toward the goal of reducing breast cancer risk.
NF-kappaB is Central to Cell Regulation and Cancer Prevention

The NF-kappaB gene signaling system is essentially a local intelligence within your cells that helps your cells adapt to stress and resolve challenges to survival. When your cells are cruising along in a happy metabolic state, then NF-kappaB has little to do beyond baseline functions. When an attack occurs on a cell, be it a pathogen, a toxin, an injury, stress chemicals, an excess amount of free radicals, or even a shortage of fuel (food) then the NF-kappaB system swings into action to orchestrate the response, similar to a 911 operator helping in a time of need. This system is vital for survival. Many of its initial steps are inflammatory in nature.
Problems occur when the NF-kappaB system cannot orchestrate a full resolution, often caused by ongoing stress, poor diet, lack of sleep, ongoing infection, ongoing toxin exposure, or other wear and tear factors. You might say the 911 operator is getting frustrated with daily calls from the same person, leaving the system chronically inflamed. Since the NF-kappaB gene signaling system is central to all other types of inflammation of any kind, this is a rather big issue.
In cancer, cells with a confused and inefficient NF-kappaB system are hijacked—it hijacks the NF-kappaB system itself, which is now used to forward the survival of the cancer cells.
Many nutrients help calm down NF-kappaB, helping it to do its job more efficiently so that it is less susceptible to being hijacked. For example, the polyphenols in green tea, quercetin, resveratrol, grape seed extract, curcumin, and blueberries all help regulate and calm down NF-kappaB. Likewise, another broad array of nutrients from the plant kingdom are called terpenes. All carotenes (beta carotene, lyopene, lutein, astaxanthan) are forms of terpenes. The tocotrienol form of vitamin E has a terpene attached to the vitamin E molecule, making it highly biologically active against breast cancer. The NF-kappaB regulating property of terpenes is widely believed as a primary mode of operation for their anticancer properties. In fact, many nutrients can tell the difference between a healthy cell and a cancer cell; they help the healthy cell survive and help to kill the cancer cell, all by “intelligent” interaction with the NF-kappaB signaling system.
What makes d-Limonene so interesting is that it is highly fat soluble and readily accumulates in fatty tissue such as breast tissue. Once it is in position it helps to fortify healthy NF-kappaB function, a useful tool for promoting breast tissue health. It is unknown what dose of d-Limonene is needed to enable enough breast tissue accumulation of d-Limonene to actually prevent breast cancer. However, researchers at the University of Arizona have proven that even 500 mg of d-Limonene per day readily accumulates in white adipose tissue, indicating that breast tissue accumulation of d-Limonene is likely at doses typical from d-Limonene dietary supplements. If people manage many aspects of their health well, then they have less inappropriate activation of NF-kappaB and would likely need a lower dose to maintain health. If a person is overweight and/or has multiple other risk factors and health issues, then a higher dose of d-Limonene makes sense.
Animal Tumor Research

Researchers demonstrated in 1984, 1986, 1989, and 1994 that d-Limonene could prevent the formation of experimentally induced breast tumors as well as eradicate existing breast tumors. It did so with very low toxicity, either from the d-Limonene or from the manner in which the cancer was being killed.
In terms of preventing the start of breast cancer, it was found that d-Limonene assisted the liver with detoxification of chemical toxins, preventing the toxins from inducing DNA damage, which led to cancer. In established cancer, d-Limonene utilizes its solvent properties to enter tumors and directly influence cell signaling to help kill the tumor. While it acts as an antioxidant for healthy cells it seems to know the difference when cancer has taken hold. It actually turns up free radical production in cancer cells to help kill them. While this seems to be yet another example of a nutrient displaying intelligent operation within the body, it is more likely that the gene signaling of the human body is quite adept at using common nutrients that have been around since the beginning of human evolution to defend itself.
Other researchers have shown that d-Limonene has anti-cancer properties for gastric cancer, liver cancer, lung cancer, pancreatic cancer, and prostate cancer.
A recent study shows that d-Limonene improves important aspects in the NF-kappaB signaling pathways, thereby preventing and reducing skin cancer. The researchers showed that d-Limonene also restored antioxidant enzyme function for healthy function.
Human Research

Extensive human research on d-Limonene and cancer is lacking.
In a 2000 study researchers at the University of Arizona found that people living in the sunny Southwest who consumed lemon peels as part of their diet, but not lemons or lemonade, had significantly reduced occurrence of skin cancer.
A few specific patients with advanced breast and colon cancer, taking high dose d-Limonene, were able to hold off progression of the cancer for up to six months. General excitement in the scientific community led to initial human clinical trials using a secondary metabolite of d-Limonene called perillyl alcohol, most likely because this compound could be made into a drug. Results were disappointing because it is rapidly cleared in the urine, requiring high doses that had too many uncomfortable side effects. D-Limonene does not have these types of problems, but there is a lack of funding for expensive human trials since no drug will result.
The anti-breast cancer properties of d-Limonene have been extensively reviewed in 1999 by researchers at Purdue University and in 2010 by researchers at the University of Arizona. Read either full-length paper by following the preceding links. These papers explain that d-Limonene exerts its anti-cancer activity by multiple mechanisms including improved immune response, improved antioxidant defense system, improved detoxification, reduction in inflammation, better regulation of the cell cycle, and induction of death signals in cancer cells.
Safety and Absorption of D-Limonene

D-Limonene is rapidly and easily absorbed by the human digestive tract. The oil is spread throughout the body with a preference for fatty tissues such as white adipose tissue, breast tissue, the liver and brain. It exerts direct metabolic activity as well as combines with oxygen to produce a variety of secondary metabolites that are also biologically active.
An oral dose of 1.6 grams (1,600 mg) in humans was mostly cleared through the urine within 48 hours. A dose of 500 mg from specially prepared lemonade was cleared within 24 hours. The biological activity of a dose of d-Limonene lasts from 12 - 24 hours. A single dose of 20 grams of d-Limonene in healthy men was found to have no toxic effects. Ongoing supplementation with 100 mg per kilogram (about 7 grams per day for an average adult) was found to have no toxic effects. Doses up to 15 grams per day have been used in human breast cancer studies with no toxic effects. High doses of d-Limonene are considered safe for human consumption, with no toxicity to the liver or kidneys.
At these higher doses a person may experience belching of the oil, which is annoying but is not a health problem. Because the nutrient has relaxing and anti-anxiety properties, higher doses may make a person tired, (which may be quite useful as a sleep aid). Because the nutrient moves peristaltic motion forward, higher doses could cause diarrhea. Because the nutrient unclogs sludge in the gall bladder, higher doses could move stagnant bile rapidly into the digestive tract, which could cause nausea. Because d-Limonene has anti-fungal properties some individuals with an overgrowth of Candida albicans could experience a “die off” from a high dose (nausea or flu-like symptoms). These symptoms have been reported in human studies, in some people, when doses reach 7 - 15 grams per day. In other words, most uncomfortable symptoms with very high dose d-Limonene are not toxic symptoms but reflect a dose that is higher than can be easily metabolized based on a person’s existing metabolic situation. If any of these should occur when taking d-Limonene, cut back the dose or discontinue for a few days, then try a lower dose.
Useful metabolic doses of d-Limonene range from 1,000 mg to 6,000 mg per day (1 – 6 grams per day).
Summary

The scientific basis to use d-Limonene as an anti-cancer nutrient, especially for breast cancer prevention and treatment, is well established in literature. It is unfortunate that billions of dollars are spent researching toxic cancer drugs when so much benefit could be had by doing the needed human research to prove the most effective dose of d-Limonene for cancer prevention as well as to help treatment in various situations. It is clear that we have a rather sick cancer industry, where putting patents on profitable drugs trumps safe and effective natural health options for people in need.
Nevertheless, no harm is done by incorporating d-Limonene into your diet, especially if it can be of assistance for other health issues that may also benefit from it. Terpenes are basic components of the human diet, used by our bodies throughout evolution to promote human health.
Originally published 10-12-2012
Please, Oh Yes--I am begging you to keep your info and this thread going; you have no idea how much it might help yourself and many others, in the future! Wishing a healing for you both.:ying:jpt
 
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