I created this thread to pose this question "Do women get as high as men do?".
Up until 1990 women were banned from clinical trails. Women are affected differently than men with pharmaceuticals. To limit the pharmaceutical's test trails, they simply removed women entirely from the results.
What they have learned in scientific journals is that women are 50 to 75 percent more likely to experience side effects. Due to a difference in amount and type of hormones in their body verses men, they have a difference experience of the drug.
Metabolism is very different in women verses men. They burn more glucose than men. Not only that but women also burn and store fats different than we do.
Women experience greater pain relief from opioid pain killers perhaps due to estrogen. Antidepressents are more potent for women because men have more binding capacity in their blood. Women may trap drugs in their fats for a longer period of time. The stomach of a women is less acidic than men, which causes them to feel the effects of a drug faster, and more powerfully. Men's kidneys filter out drugs fatter than women which is why they tell women to wait longer before taking a second dose. Benzodiazepines are designed to dissolve in lipids to cross from the blood stream into the brain and since women have more body fats drugs tend to linger longer.
From animal studies to clinical trials, drugs are often tested on males only. Yet eight out of 10 drugs pulled from the market by the fda between 1997 and 2001 posed greater health risks for women than men, according to a government report. This testing bias can be unwitting or intentional—many clinical trials exclude women because their different hormones are considered a “confounding variable.” Pregnant women also typically do not take part in clinical trials for safety reasons, but mounting evidence suggests that their hormonal changes can alter the effects of certain drugs.
I really did not know the answer when i posted this question on the forum. I was curious to see if you too felt there would be a difference. The strongest response from the women here is that they are "affected stronger than men". How better to get to the right answer than get right to the source. What was interning was all the men's responses, and was not expecting men to come here and respond. I decided to look up this question in medical journals, and found the information very easily. It seems this is an old question that was discovered in medical trials, and the answer scared them so much they excluded all women from their trials and did not change this until 1990.
A person really can not say that women merely need more to get as high as us. It might be better said that men need more stash so they experience the high as well as women. Even then, it would not be the same, women are just different than men in a lot of wonderful ways, and this os one of them.