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Strong CBD/THC to help with symptoms of Pneumonia (and Coronavirus?)

GMT

GMT

The Tri Guy
Veteran
420giveaway
With asthma I do find weed helps to clear the lungs out, cigs on their own don't. But with chest infections, esp the h1n1 that went around a while back, no smoking at all was wise or even possible. I wouldn't advise anything in regards to pneumonia, that has to be between the doctor and the patient.
 
GoatCheese

GoatCheese

Active member
Veteran
DarthSidious said:
I don't think it works this way. Otherwise, Netherlands would be clean of Covid-19, lol
Click to expand...
They don't have too much CBD-rich bud in Dutch coffeeshops, they have some but not that much. ..most of the weed in coffeeshops is THC-rich weed, so i don't see that Holland is such a good example..
 
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GoatCheese

GoatCheese

Active member
Veteran
djav59 said:
No smoke, oral or topical only .
Click to expand...
If the infection hits the lungs how is a topical gonna help? Where are you gonna rub it, on your chest? Is this what you have done yourself while having a pneumonia or just something that you came up with w/o any personal experience?



Smoking sure helped me to feel more comfortable, but some of you anti-smoke people just seem to know better? No personal experience with pneumonia and CBD-rich weed, but still you know what works and what makes it worse.
..Maybe god gave me a pair of proper lungs fit for a man, instead of a pair for old women, i dunno.:)




If anyone has personal experiences with what i suggested in the starting post, do chime in. ..if a topical CBD-rich cream rubbed on your chest helped, please report that as well.



Take care everyone. Glad it, Covid, doesn't seem to be as deadly/dangerous as the early warnings predicted.
 
G

Galaxy420

Active member
the plant cannabinoids seem to be a way to prevent the Cytokine storm as an anti oxidant ... but if you are already sick then ingesting the plant cannabinoids may suppress the immune system making the virus replicate further ETC... we are still unsure how the phytocannabinoid effects the Gi proteins of the cells
 
GoatCheese

GoatCheese

Active member
Veteran
[FONT=&quot]Southern Alberta researchers say medical cannabis could help fight COVID-19[/FONT]
Published Tuesday, April 21, 2020
https://calgary.ctvnews.ca/southern...-cannabis-could-help-fight-covid-19-1.4906249
(...)
The Kovalchuks say, based on the preliminary data and pending further investigations, anti-inflammatory high-CBD cannabis extracts can modulate the levels of the receptors in highly relevant tissues, such as the mouth, lungs and intestinal cells.
One of the receptors, known as ACE2, has now been shown to be a key gateway, to how the COVID-19 virus enters the body.
 "The virus has the capacity to bind to it, and pull it into the cell, almost like a doorway," Olga says.

Other key receptors allow the virus to enter other cells more easily and multiply rapidly. But some cannabis extracts help to reduce inflammation and slow down the virus.

"Imagine a cell being a large building," says Igor. "Cannabinoids decrease the number of doors in the building by, say, 70 per cent, so it means the level of entry will be restricted. So, therefore, you have more chance to fight it."

The early discoveries indicate the cannabis extracts could be used in inhalers, mouthwash and throat gargle products for both clinical practice and at-home treatment.

The Kovalchuks haven’t tested the effects of smoking cannabis and say you won’t find any of these extracts at your local weed store.
 "The key thing is not that any cannabis you would pick up at the store will do the trick," says Olga.

Over the past four years, they have tested hundreds of extracts, but only a small percentage have proven effective.
 Those extracts contain high concentrations of CBD, but very low levels of THC, so users would not experience a "high."

The Kovalchuks say it’s a completely natural product, and has no side effects.

The research was conducted in partnership with the University of Lethbridge, Pathway RX Inc., and Swysh Inc., two companies focused on researching and developing custom cannabis therapies. Many of the cannabis varieties have been patented and are currently licensed to Pathway Rx’s partner Sundial Growers Inc., a Calgary-based cannabis licensed producer.

 They stress their data is based on human tissue models and the next step would be to do clinical trials, something Igor says they are actively pursuing.

"Given the current dire and rapidly developing epidemiological situation, every possible therapeutic opportunity and avenue needs to be considered."
"We need to bring it to the people," says Olga. "We need to fight the beast."
 
GoatCheese

GoatCheese

Active member
Veteran
Does marijuana help sick recover from coronavirus?
The hospital is now recruiting patients to participate in a more extensive study to explore CBD’s effect.

By JERUSALEM POST STAFF
MARCH 2, 2021 14:27
https://www.jpost.com/health-science...navirus-660685

A research team at Rabin Medical Center at Beilinson tested CBD cannabidiol on a group of 11 patients in serious condition with the novel coronavirus and found what they claim could point to promising results.
Out of the 11 patients, 8 saw improvement in the infections they were suffering from - and which are known to cause death in COVID-19 patients – leading to their release sometime between seven and 30 days later. The other three patients died of their illness.

The researchers led by Dr. Moshe Yeshurun, head of the Bone Marrow Unit at the hospital, stressed that the findings were initial and too limited to derive a concrete conclusion about cannabis’s influence on the term of the illness but that the findings did justify continued research with a larger group of COVID-19 patients.

Yeshurun and his team decided to test CBD on COVID patients due to the success they have seen in reducing infections in patients who have undergone bone marrow transplants with CBD. Patients who receive bone marrow transplants are at risk of developing complications when the transplanted cells from the donor identify the recipient as foreign.

This can trigger a reaction that leads the donated cells to attack the patient who received the transplant. Yeshurun and his team have found that Cannabidiol minimizes that risk.
“After giving the cannabis oil we saw a drop in signs of the infection and this is definitely encouraging and gives a foundation to continue the research,” Dr. Iliya Kagan, head of the hospital’s Intensive Care Unit, said of the recent study on coronavirus patients
Kagan said that after the oil was administered the decline of some of the patients – who were all in serious condition – appeared to stop “although it is still premature to determined with certainty that it is a result of the cannabis.”

Kagan said that the hospital is now recruiting patients to participate in a more extensive study to explore CBD’s effect and if it will support the initial optimistic findings.
 
GoatCheese

GoatCheese

Active member
Veteran
Has anyone had Covid and treated it with CBD-rich cannabis in any way (vape, bong, edibles etc.)??
Cannabis for Covid-19 Victory! Stay safe, people :tiphat:
 
GoatCheese

GoatCheese

Active member
Veteran
St. Phatty said:
A neighbor had Covid19 for about a month.

He used Cannabis as a palliative, said it really helped.
Click to expand...

Hey that’s great news and thanks for sharing it.

Did your neighbor mention what strain(s) he/she was using? Many compounds in cannabis are antiinflamatory, antibactrial and/or antiviral so it would be great to know what strains helped with COVID/pneumonia symptoms.
Was it THC rich or high-CBD? Flower or some kind of extract?
..do you mind asking about it if he/she didn’t mention it?

Also, please ask if he/she was vaping it or smoking it or what?
- What kind of amounts daily? For how long?
- And if he/she can describe HOW cannabis helped with the COVID-symptoms. Did it help with breathing? Did it feel like it eased the inflammation in the lungs?

Would be great contribution to get such info posted into this med-cannabis thread, if you don’t mind having a quick chat with your neighbor and maybe writing down few notes. ..You don’t have to write a whole book about. Heh-he:)

Yea, it would be great benefit to get more of this kind of info/data posted in this thread. It would be valuable stuff in these times, esp. if some people don’t wanna get vaccinated and want to try coping with COVID using CBD/THC rich cannabis.
Cheers.:tiphat:
 
S

St. Phatty

Active member
GoatCheese said:


Hey that’s great news and thanks for sharing it.

Did your neighbor mention what strain(s) he/she was using? Many compounds in cannabis are antibactrial and/or antiviral so it would be great to know what strains helped with COVID/pneumonia symptoms.
Was it THC rich or high-CBD? Flower or some kind of extract?
..do you mind asking about it if he/she didn’t mention it?
Click to expand...



He mostly likes concentrates. Kif & Extracts.
 
GoatCheese

GoatCheese

Active member
Veteran
Cannabis compounds can stop the virus that causes COVID-19 from entering human cells by binding to the spike protein and blocking it from infecting people, study finds
  • The compounds are found in hemp and can be taken orally or combine with the coronavirus vaccine
  • The compounds, a pair of cannabinoid acids, bind to the SARS-CoV-2 spike protein
  • This blocks the virus from infecting human cells, thus stopping COVID-19
12 January 2022
https://www.dailymail.co.uk/sciencet...udy-finds.html

Specific cannabis compounds can prevent the virus that causes COVID-19 from entering human cells.
Researchers at Oregon State University identified a pair of cannabinoid acids that bind to the SARS-CoV-2 spike protein, blocking a critical step in the process the virus uses to infect people.
The team found the cannabis compounds, which can be taken orally and are abundantly found in hemp, blocked the alpha and beta variants from infecting the human cells - but the team notes those are the only two variants studied in this research.

This means, according to the team, the compounds could prove successfully in blocking other coronavirus strains.
Richard van Breemen, a researcher with Oregon State's Global Hemp Innovation Center and study lead, said in a statement: 'These cannabinoid acids are abundant in hemp and in many hemp extracts.
'They are not controlled substances like THC, the psychoactive ingredient in marijuana, and have a good safety profile in humans.
'And our research showed the hemp compounds were equally effective against variants of SARS-CoV-2, including variant B.1.1.7, which was first detected in the United Kingdom, and variant B.1.351, first detected in South Africa.'

The specific compounds are cannabigerolic acid, or CBGA, and cannabidiolic acid, CBDA, and the spike protein is the same drug target used in COVID-19 vaccines and antibody therapy.
SARS-CoV-2, which is characterized by crown-like protrusions on its outer surface, features RNA strands that encode its four main structural proteins – spike, envelope, membrane and nucleocapsid – as well as 16 nonstructural proteins and several 'accessory' proteins, van Breemen said.
'Any part of the infection and replication cycle is a potential target for antiviral intervention, and the connection of the spike protein's receptor binding domain to the human cell surface receptor ACE2 is a critical step in that cycle,' he said.
'That means cell entry inhibitors, like the acids from hemp, could be used to prevent SARS-CoV-2 infection and also to shorten infections by preventing virus particles from infecting human cells.
'They bind to the spike proteins so those proteins can't bind to the ACE2 enzyme, which is abundant on the outer membrane of endothelial cells in the lungs and other organs.'
And using compounds to block virus-receptor interaction is nothing new: it has been used to treat HIV-1 and hepatitis.

'One of the primary concerns in the pandemic is the spread of variants, of which there are many, and B.1.1.7 and B.1.351 are among the most widespread and concerning,' said van Breeman.
'These variants are well known for evading antibodies against early lineage SARS-CoV-2, which is obviously concerning given that current vaccination strategies rely on the early lineage spike protein as an antigen.
'Our data show CBDA and CBGA are effective against the two variants we looked at, and we hope that trend will extend to other existing and future variants.'
 
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