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Old 11-21-2020, 03:47 PM #11
Lester Beans
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I'm not sure wtf I just read. OP is hung up on myth that only "pure" sativa is any good. Best of luck
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Old 11-21-2020, 10:38 PM #12
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Originally Posted by flylowgethigh View Post
How about 'splainin what's the chemical difference between a pure Sative and an Indica. What different parts of the brain are being affected, that Indica isn't reaching? Does CBD have to be in the equation? That would be interesting material.
Different enzymes converting different fatty acids into different sugar alcohols that help endocannabiboids regulate functions they currently aren't regulated, which in most cases is the (in)hibition of other enzymes. Most health issues are enzyme deficiencies/excesses. Not being high is a health issue to a species that coevolved with Cannabis.

D9thc doesn't get you high. It has to be converted. That's why edibles hit different, higher conversion to 11-hydroxy-thc due to more enzymes.

Modern commershica weed is antagonistic to itself, enzymes stripped out in favor of faster glucose production. Smoke yourself sober on one hit and call the side effects of trying to get higher "gettin high". Today's weed is so bad, with such good genes.. You could literally spray any of these pastry crust strains with enzymes and get them to smell like skunk ass...
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Old 11-22-2020, 01:51 AM #13
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Drewsif that's the type of comment that makes this forum special. Rock the fuck on brother, good stuff! Much love
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Old 11-22-2020, 04:51 PM #14
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Originally Posted by sbeanonnamellow View Post
Cannabis sativa L. - Botany and Biotechnology by Chandra, Lata, and ElSohly



Table 1.1 lists Sativa-types as: Widespread (southern Asia), relatively long (late maturing), often in semi-tropical regions, relatively tall (2-4 m), diffusely branched (longer internodes); less dense, more elongated "buds", narrow leaflets, lighter green leaves, relatively late maturation, relatively pleasant aroma (often described as "sweet"), variable ease of detachment of heads from secretory glands, little or no CBD, and relatively euphoric: a "cerebral high" promoting energy and creative thought (occasionally panic attacks in inexperienced users, or a drained feeling)

Table 1.1 lists Indica-types as: Restricted (Afghanistan, Pakistan, northwest India, Relatively short (early-maturing), adapted to relatively cool, arid regions, relatively short (1-2 m), bushy (short internodes), often conical; very dense, more compact "buds", broad leaflets, dark green leaves, relatively early maturation, relatively poorer aroma (sometimes described as "sour" and "acrid", easily detached heads from secretory glands, substantial CBD, and relatively sedative: physically relaxing, producing lethargy.

I kinda hate how they continually say marijuana but all things considered a pretty decent resource. The book suggests that CBD is definetly in the equation of classification of cannabis in relation to agricultural, biotechnological, medical, and recreational utilization.
I typed this before I read Drewsif's reply. Finally we are getting a theory out there. Is this described in scientific literature, and if so any pointers?

More Sativa / Indica BS. I get the effects thing, and hitting some "heavy" Indica before a hot shower and bed is one of lifes great pleasures, but... what is the chemistry that makes these effects different. I have not seen that explained, or even explored, in the literature. Why the different effects? I will venture this, in edibles there is no distinction and "Sativa" or "Indica" edibles are more BS.
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Old 11-22-2020, 07:04 PM #15
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Originally Posted by flylowgethigh View Post
I typed this before I read Drewsif's reply. Finally we are getting a theory out there. Is this described in scientific literature, and if so any pointers?

More Sativa / Indica BS. I get the effects thing, and hitting some "heavy" Indica before a hot shower and bed is one of lifes great pleasures, but... what is the chemistry that makes these effects different. I have not seen that explained, or even explored, in the literature. Why the different effects? I will venture this, in edibles there is no distinction and "Sativa" or "Indica" edibles are more BS.
Clearly you have never tried a pure sativa.
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Old 11-22-2020, 07:26 PM #16
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Originally Posted by flylowgethigh View Post
I will venture this, in edibles there is no distinction "Sativa" or "Indica"
Some narrow leaf dominant long flowering types can pick me up with just a cup of tea made from a few raw fans. I’ve never found a broad leaf dominant short flowering var that can do this, even when encrusted with trichs.

I’ve read that every generation of cbd dominant plants have to be genetically modified in order to maintain low enough levels of thc to be considered hemp as the plant uses thc as sunscreen so continues to produce it out of necessity in future generations.

It makes sense then that long flowering plants from near the equator or high altitude would require more sunscreen and therefore have higher levels of thc/thcv than cbd which competes for the same food source, but interestingly they tend to also have an excess of cbg which is not often found in the short flowering types. So it can’t just be competition for cbg that is preventing cbd production in these plants.

More likely it is because they have never been exposed to genetically modified industrial hemp resulting in some of the medicinal effects that have been lost in modern hybrids still being present.

The logic of blaming cbd fails though when you look at short flowering broad leaf dominant plants that have high levels of cbd but have somehow retained many medicinal attributes vs the modern couch lock hybrids which have low to no cbd or medicinal value.
Perhaps in this case it was keeping the plants it a sterile environment and feeding them salt that was responsible for the changes in effects rather than genetic editing or modification, I’d love to know.

It’s my hope that as technology improves, we will more easily identify contaminated or modified genetics and breed them out of the pool. This is more important now than ever since the invention of plants that produce virus induced water soluble cannabinoids and proteins. We are entering into a whole new world of genetic pollution and it will take a combined effort between growers and patients to save what remains of this plant.
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Old 11-22-2020, 07:53 PM #17
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Old 11-22-2020, 07:55 PM #18
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Quote:
Originally Posted by OnlyPureSativas View Post
Clearly you have never tried a pure sativa.
First real hit of sativa came out of a ghord water pipe....exhaled through my nasal passage.......was more like speed then cannabis lol
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Old 11-22-2020, 08:09 PM #19
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Originally Posted by flylowgethigh View Post
I typed this before I read Drewsif's reply. Finally we are getting a theory out there. Is this described in scientific literature, and if so any pointers?

More Sativa / Indica BS. I get the effects thing, and hitting some "heavy" Indica before a hot shower and bed is one of lifes great pleasures, but... what is the chemistry that makes these effects different. I have not seen that explained, or even explored, in the literature. Why the different effects? I will venture this, in edibles there is no distinction and "Sativa" or "Indica" edibles are more BS.
The quote was pulled from the aforementioned book publication. The authors (ElSohly) of the book are some of, if not the only, federally approved researchers of cannabis in the United States at the University of Mississippi. If I recall, they even sourced some some stuff from Sam back in the day via Hortipharm though I could easily be getting that confused with the partnership of Geoffrey Guy and G.W. Pharmaceuticals with respect to germplasm acquisitions.

The book is the most current publication that I know of and uses previous publications on Cannabis to pull information from. For example, a lot of the nomenclature references are from Clarke and Merlin's - Cannabis Evolution and Ethnobotany, among other literature resources previously published.

It's very scientific based to the point there are chapters dedicated to micropropagation of cannabis. It's more textbook style than most others, very....what's a good word, scholarly? Educational?

It's the type of book you'd get assigned in an advanced Cannabis class if offered at a local college. Cannabis 202 or something like that. There's a bunch of great information but there's also a lot that is left to be desired. Given their license permission, some of the pictures looked like they could use a couple of icmag members to set up their grows.

It's an ongoing study, and I'm certain that in the future it will be spelled out better but at the moment the research is really in it's infancy.

There are a couple other publications from Springer publishing that I haven't scooped up yet that might provide more insight. Phytocannabinoids - Unraveling the Complex Chemistry and Pharmacology of Cannabis Sativa as well as Recent Advances in Cannabinoid Physiology and Pathology

Even still, there's enough empirical evidence in my opinion to differentiate the two types (sativa and indica) as they relate to expected user experience and perception of effects. It's one of those, in my opinion, we know what's going on we just have to prove it in a scientific language.

Gravity is observable, but it wasn't put into a scientific language until it was. Doesn't mean gravity didn't exist until then.

The future of cannabis research is bright. Gone are the day's where THC reigns supreme as the end all be all. Couple years ago we learned of terpenes and their entourage effects via Ethan Russo. Old timers would smell a bag and choose which they want based on smell alone, it's the whole gravity thing again. The old timers didn't know limonene or ocimene influenced this or that. It was empirical evidence that led them towards their choice of which lid to scoop up.

Also worth noting, those old school sativas weren't chock full of THC like todays varieties with 30+% THC. They had a nuance to their makeup that has been strayed far from.

Sativa-types are where it's at for some, indica-types for others. Me though, I wanna be high and soaring. Energized and feeling great. Laughing giggling, loving life.

Sometimes a heavy indica is helpful, but for me it's more the exception than the rule. Everyones mileage certainly varies, different strokes for different folks.

If you can, I'd suggest scooping up some of those publications or see if your local library has them or can order them. Perhaps even better, reach out and write to some or a few of the authors of those books and pose your questions to them. They may very well have more insight that hasn't been published yet. Much love
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Old 11-23-2020, 05:53 AM #20
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This one must be the ultimate stealth strain
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