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Industrial Hemp in Oregon

Aota1

Member
If a hemp farmer has a crop test a little too high in thc could this cannabinoid free variety be used to remediate that down to a usable number? Is that allowed?
 
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PDX Dopesmoker

Active member
The main uses of cannabinoid-free plants: (1) smoking for flavor without a cannabinoid experience (terpenes also alter mood); (2) using as a blending material to maintain federal legality (0.3% THC) without losing flavor; (3) an actual placebo that looks and tastes like the "real thing" in the use of clinical studies. Most importantly though...

We are replacing hops with a plant that is much easier to grow, harvest, and breed, while increasing the total relative oil yield per acre. Cannabis for the win.

Thanks, I couldn't think up a decent reason myself, but you seemed excited about it, so I knew it was something special. Its kinda hilarious that you bred a workaround for a regulatory burden.
 
R

Robrites

Cannabis pain relief without the 'high'

Cannabis pain relief without the 'high'

Canadian researchers pinpoint the mechanism of cannabidiol for safe pain relief without side effects
McGill University Health Centre


In the wake of cannabis legalization, a team of scientists at the Research Institute of the McGill University Health Centre (MUHC) and McGill University have delivered encouraging news for chronic pain sufferers by pinpointing the effective dose of marijuana plant extract cannabidiol (CBD) for safe pain relief without the typical "high" or euphoria produced by the THC. The findings of their study have been published in the journal PAIN (The Journal of the International Association for the Study of Pain).
Cannabis indica and sativa are the two main cannabis strains that produce the pharmacological principles known as tetrahydrocannabinol (THC) and cannabidiol (CBD). Dr. Gabriella Gobbi's team demonstrated that CBD does not act on the CB1 cannabinoid receptors like THC but through the mechanism that binds specific receptors involved in anxiety (serotonin 5-HT1A) and pain (vanilloid TRPV1). Researchers were able to extrapolate the exact dosage of CBD displaying analgesic and antianxiety properties without the risk of addiction and euphoria classically produced by the THC.
"We found in animal models of chronic pain that low doses of CBD administered for seven days alleviate both pain and anxiety, two symptoms often associated in neuropathic or chronic pain," says first author of the study Danilo De Gregorio, a post-doctoral fellow at McGill University in Dr. Gobbi's laboratory.
Lead author Dr. Gobbi, a researcher in the Brain Repair and Integrative Neuroscience (BRaIN) Program of the RI-MUHC, sees this as advancement for the evidence-based application of cannabis in medicine with CBD offering a safe alternative to THC and opioids for chronic pain, such as back pain, sciatica, diabetic, cancer and post-trauma pain.
"Our findings elucidate the mechanism of action of CBD and show that it can be used as medicine without the dangerous side effects of the THC," says Dr. Gobbi, who is also Professor of Psychiatry at the Faculty of Medicine at McGill University and staff psychiatrist at the MUHC. "This research is a new advancement for an evidence-based application of cannabis in medicine."
Despite widespread public usage, little clinical studies exist on CBD, which became legal in Canada on October 17, 2018, following the passage of Canada's Cannabis Act.
"There is some data showing that CBD provides pain relief for humans but more robust clinical trials are needed ," says Dr. Gobbi, a recent grant recipient for her study of the pharmalogical effects of CBD.
###​
About the Study
The study 'Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain' was co-authored by Danilo De Gregorio (First author); Ryan McLaughlin; Luca Posa; Rafael Ochoa Sanchez; Justine Enns; Martha Lopez Canul; Matthew Aboud; Sabatino Maione; Stefano Comai et Gabriella Gobbi (Corresponding author).
DOI: 10.1097/j.pain.0000000000001386
This work was supported by a matching grant (PSR-SIIRI) from the Ministère de l'Économie Science et Innovation du Québec (MESI, Program PSR-SIIRI) and Aurora Cannabis Inc.



https://www.eurekalert.org/pub_releases/2018-10/muhc-cpr102418.php
 

PDX Dopesmoker

Active member
socioecologist, You seem to be having fantastic success in targeting specific cannabinoids in breeding, including eliminating them completely. Have you tried aiming at specific terpenes yet and is that process similar to targeting specific cannabinoids?
 

Apache123

Member
What are hemp prices going for in Oregon? Per pound? I would imagine its based of off test results of the finished material. What is demanding the highest price? High CBD? CBG? CBN?

Also, I have heard that California/FDA will require any Hemp/CBD etc for human consumption will have to be grown indoors/greenhouses. What say you?

Thank you!
 
socioecologist, You seem to be having fantastic success in targeting specific cannabinoids in breeding, including eliminating them completely. Have you tried aiming at specific terpenes yet and is that process similar to targeting specific cannabinoids?

Great question, and yes, we target specific terpene combinations in our work as well. Many of the mother plants we use to create our CBD lines are farnesene dominant--I haven't seen any other commercially available varieties carrying this trait. We are shifting towards qPCR for early screening of terpene synthases in our hops-replacement breeding program.

Locking in general terpene profiles is attainable. Locking in really specific terpene profiles is difficult, if not impossible. The main problem is that terpene synthases have been found to produce multiple compounds (research done by Jon Page's group at Anandia labs). This helps to explain why environment and nutrition seem to alter flavors so dramatically, even in identical clones. The paper describing these behaviors is publicly available and a really cool read.

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173911
 

PDX Dopesmoker

Active member
Has there been any progress or anything interesting on the CBDV front? There are a couple active threads in other parts of the site about THCV and it reminded me that I've never really seen much at all anywhere about CBDV.
 
Anyone who is interested in this thread might enjoy this podcast
https://media.blubrry.com/shapingfi...rd_The_Nexus_of_Medical_Cannabis_and_Hemp.mp3




Thank you. I will check this out.



We are in the process of licensing an Lp in Canada will many acres of Ag land avail to do hemp. Never done hemp and have lots of questions. Most important would be..What kind of revenues can be generated per acre? What are the uses. I have very little knowledge in the hemp processing tree..
 
Has there been any progress or anything interesting on the CBDV front? There are a couple active threads in other parts of the site about THCV and it reminded me that I've never really seen much at all anywhere about CBDV.

Yes, most definitely. Mark Lewis' group at Napro has a great variety that is equal parts CBD to CBDV--some of their licensed cultivators used it to win at the Emerald Cup last year. We'll have our lines out for field trials summer of 2020.

It has taken some time to develop them. Propyls (i.e. the varins) are a little more finicky than pentyls (the "regular" acid forms we are all used to); because of that, the order of operation is to isolate the pentyls first, then work to increase the propyl fraction. In other words, you have to first find good CBD, CBG, CBC, THC, etc. candidate lines, then outcross or inbreed towards the target of increasing respective CBDV, CBGV, CBCV, THCV, etc. Even with "substantially pure" propyl varieties, there is significant variation of the total "V" proportion present between siblings within seed lines. Some can be 20/80 varin/pentyl, while others are 80/20; the variation is normally distributed.

The lack of CBGVA reference standards have also been a bit of an impediment. It definitely reinforces the reality that even the best cannabis labs lose their usefulness to breeders attempting to isolate compounds rather quickly--our most interesting targets today are just unknown spikes on a chromatogram.

For what it's worth, I can also confirm what you were reading in those other threads that THCV is most definitely NOT psychoactive.
 

PDX Dopesmoker

Active member
Thanks for the briefing, is the lack of reference standards because of others not sharing what they know or because you're exploring new chemicals which people haven't had access to in high concentration before?
 

englishrick

Plumber/Builder
Mentor
ICMag Donor
Veteran
Yes, most definitely. Mark Lewis' group at Napro has a great variety that is equal parts CBD to CBDV--some of their licensed cultivators used it to win at the Emerald Cup last year. We'll have our lines out for field trials summer of 2020.

It has taken some time to develop them. Propyls (i.e. the varins) are a little more finicky than pentyls (the "regular" acid forms we are all used to); because of that, the order of operation is to isolate the pentyls first, then work to increase the propyl fraction. In other words, you have to first find good CBD, CBG, CBC, THC, etc. candidate lines, then outcross or inbreed towards the target of increasing respective CBDV, CBGV, CBCV, THCV, etc. Even with "substantially pure" propyl varieties, there is significant variation of the total "V" proportion present between siblings within seed lines. Some can be 20/80 varin/pentyl, while others are 80/20; the variation is normally distributed.

The lack of CBGVA reference standards have also been a bit of an impediment. It definitely reinforces the reality that even the best cannabis labs lose their usefulness to breeders attempting to isolate compounds rather quickly--our most interesting targets today are just unknown spikes on a chromatogram.

For what it's worth, I can also confirm what you were reading in those other threads that THCV is most definitely NOT psychoactive.

This is a fantastic thread,, full respect to contributors,,, who's the best company for me to check out when buying various cbg and other lines rich in the most uncommon constituents

Thanks
 
R

Robrites

Oregon hemp industry poised for big growth after feds sign off

Oregon hemp industry poised for big growth after feds sign off

Hemp now has something marijuana doesn’t: federal approval.
A provision of the $867 billion farm bill Congress approved this week removes hemp from the list of federally controlled substances and treats the low-THC version of the cannabis plant like any other agricultural crop. If President Donald Trump signs the legislation as expected, it’s projected to rev up already-explosive growth in an industry that has a footprint in 23 states.
The curious only have to look to Oregon to see the potential. Hemp production was effectively legalized here in 2015 as part of a pilot project authorized by that year’s farm bill. Since then, the number of licensed growers has climbed from 13 to 584, and hemp acreage has swelled from essentially zero to more than 11,000 acres, said Sunny Summers, the resident cannabis expert at the Oregon Department of Agriculture.
The state’s hemp farmers are excited about their prospects, said Courtney Moran, a Portland lawyer who has long lobbied for legalization. “We’ve been living under prohibition for 81 years,” she said.
The U.S. hemp market is projected to triple, to $2.5 billion, by 2022, according to New Frontier Data, a cannabis market research firm. More than half of those sales are tied to growing demand for cannabidiol, or CBD, a non-psychoactive compound that many see as a way to better health.
“People are smoking it, not because they get high, but because they get healed,” said Bruce Cohen, chief executive officer of Hemp Inc., a large processor and grower in Medford.
Legalization also is “a huge deal" because of the domino effect, said Sean Murphy, an analyst for New Frontier Data who’s tracked the industry since its infancy in 2015. “Banks can get involved now and if banks get involved, then credit card processors get involved — and if that happens, then big box stores like Target and Wal-Mart get into it. All these big players are going to come in.”
Approval at the national level also brings a host of benefits that the pot industry has yet to see. Hemp farmers will be able to buy crop insurance, apply for loans and grants, and write off their business expenses on their taxes like any other farmer.
Some old-line Oregon farm families are making the switch. David Henze helps run Coleman Agriculture in Gervais, which replaced 17 acres of grass seed land with hemp last year and will plant 100 acres of hemp in 2019. “The farm bill really opens things up,” Henze said. “The pricing seems to be holding even with the big increase in production.”
Federal legalization means those who sell dried flower or CBD-infused products made from hemp can now ship across state lines without fear of prosecution as long as they are careful not to run afoul of the U.S. Food and Drug Administration.
Many did so before, but always looked over their shoulder because the law was unclear.
Michelle and Scott Fields, who run an organic hemp farm outside Grants Pass, include a detailed letter to law enforcement in each package they ship that explains the dried flowers inside may look a lot like pot, but actually can’t get anyone high.
“Probably the best part of this is that everybody can take a sigh of relief and not worry about that gray area anymore,” said Michelle Fields, who worked in real estate until three years ago, when she and her husband started Fields of Hemp LLC.
Hemp generally refers to cannabis plants that have little if any THC, the psychoactive substance in marijuana that gets people high. Hemp has been used to make clothing, paper and a host of other products, but the market showing impressive growth is health and wellness. Hemp extracts – specifically CBD -- can be processed into powder, oil or cream and incorporated into products like anti-anxiety compounds, stress relievers and analgesics for chronic pain.
Oregon Sens. Ron Wyden and Jeff Merkley helped push through the legalization. They worked with Senate Majority Leader Mitch McConnell, R-Kentucky, to ensure the bipartisan Hemp Farming Act of 2018 was included in the final version of the farm bill.
The Hemp Farming Act clearly defines hemp as an agricultural commodity and removes it from the list of controlled substances. It also gives states the opportunity to become the primary regulators of hemp production and normalizes the crop.
Oregon legalized cannabis three years ago. The market has since bifurcated into two major parts: recreational and medical marijuana that contains THC, and hemp, that is rich in CBD but has negligible levels of THC.
The Oregon Liquor Control Commission regulates the recreational market, which includes more than 1,100 growers, 22 labs, 207 processors and 605 retailers.
The Oregon Department of Agriculture registers the hemp sector, where rapid growth is partly attributed to falling prices and too much competition in the recreational market, Summers said.
The Associated Press contributed to this report.
– Jeff Manning | jmanning@oregonian.com | 503-294-7606


https://www.oregonlive.com/politics...oised-for-big-growth-after-feds-sign-off.html
 
R

Robrites

FDA casts shadow on hemp win, calling CBD products illegal

FDA casts shadow on hemp win, calling CBD products illegal

SEATTLE (AP) — The hemp industry still has work ahead to win legal status for hemp-derived cannabidiol, or CBD oil, as an ingredient in food or dietary supplements despite the big farm bill President Donald Trump signed this week designating hemp as an agricultural crop.
CBD oils have become increasingly popular in lotions, tinctures and foods, but their legal status has been murky and the Food and Drug Administration has sent warning letters to some companies making health claims for CBD.
In a statement following Thursday’s bill signing in Washington, FDA Commissioner Scott Gottlieb restated his agency’s stance that CBD is a drug ingredient and therefore illegal to add to food or health products without approval from his agency.
“Selling unapproved products with unsubstantiated therapeutic claims is not only a violation of the law, but also can put patients at risk, as these products have not been proven to be safe or effective,” Gottlieb wrote.
CBD is a non-psychoactive compound found in hemp, a version of the cannabis plant that is low in THC, the part of cannabis that gives pot its high.
An FDA-approved drug for the treatment of seizures, Epidiolex, contains cannabis-derived CBD. GW Pharmaceuticals’ syrup became the first prescription drug derived from the cannabis plant in June.
The FDA statement also specified parts of hemp that are safe as food ingredients, but the CBD stance disappointed advocates. Courtney Moran, a lobbyist for Oregon hemp farmers, said she plans to work with U.S. Sen. Ron Wyden, an Oregon Democrat, to nudge the FDA toward greater acceptance of CBD.
“We do hope the FDA does clear a pathway for these products that have already hit store shelves and are out in the marketplace,” Moran said. She said it’s an “opportunity for industry to educate the FDA.”
The FDA statement said three ingredients derived from hemp — hulled hemp seeds, hemp seed protein and hemp seed oil — are safe as foods and won’t require additional approvals, as long as marketers do not make claims that they treat disease.
Hemp, like marijuana, already was legal in some states before Trump signed the farm bill. But now hemp farmers will be able to buy crop insurance, apply for loans and grants, and write off their business expenses on their taxes like any other farmer.
___
Follow AP Medical Writer Carla K. Johnson on Twitter: @CarlaKJohnson


https://apnews.com/68a5b1d3181e44d180382b273f6187c4
 
R

Robrites

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Notice of Public Hearing


Division 25 - Industrial Hemp



Date and Time: Tuesday, January 15, 2019, 10:00 a.m.

Location: Oregon Liquor Control Commission
9079 SE McLoughlin Blvd., Portland, OR 97222

Presiding Officer: Bryant Haley
Phone: 503.872.5136
Fax: 503.872.5110
Email: bryant.haley@oregon.gov

Notice of Proposed Rulemaking, including Statement of Need and Fiscal Impact
Division 25 of Chapter 845 of the Oregon Administrative Rules sets forth the privileges and prohibitions for licensees and permittees of the Commission regarding the recreational cannabis market. The revisions within this package were
made to implement the changes made by the 2018 Oregon legislature (HB 4089) relating to industrial hemp.


A subsequent two week comment period will be held after the hearing; all written comments must be received by 5:00 p.m. on Tuesday, January 29, 2019.
 

pipeline

Cannabotanist
ICMag Donor
Veteran
Considering getting into cbd hemp farming. May plant an acre or 2 in 2020 or 2021. Need to do some research and get permits!


Is there anywhere I can buy cbd oil extracted from hemp from Oregon CBD seed?


Is spagyric the best extraction method?


This is where I got my first cbd recently. Infowars sponsor Washington's Reserve, which is private labeled cbd oil from EnerHealth Botanicals Longmont, CO.



Seems to have good medical benefit. I use it, but I'm also sourcing it for my brother who has early onset multiple sclerosis.



https://www.washingtonsreserve.com/about-our-hemp-cbd-products/our-extraction-process.html


_________________________________________________
Our Extraction Process
Using The Spagyric Method
At Washington’s Reserve, we produce “raw” living products. We are able to apply our experience and holistic approach, coupled with scientific knowledge, to create the widest-spectrum cannabidiol (CBD)-enriched extract on the market. This means that we use the whole hemp plant, retaining all of the hemp’s naturally occurring beneficial compounds.
We begin with organically grown hemp, grown in the Colorado soil. This ensures a rich mineral content to increase the nutritive value of our extract, as well as creating the cleanest possible product. This is especially important in creating CBD-enriched extracts because the same process that concentrates these target therapeutics can also concentrate any pesticides that may be present in the starting material.
Next, we extract a wide spectrum of the hemp therapeutics, including the many cannabinoids and valuable terpenes, using organic grape alcohol. We keep this process below 100 F° to protect the delicate constituents. This also ensures that not all of our cannabinoid acids are decarboxylated.*
In a process that adapts the ancient wisdom of alchemy and marries it to modern chemistry practices, we then run a second extraction that targets the rare earth mineral salt content that was bound up in the plant’s matrix. These rare earth mineral salts are then added back into the final extract. This completes what we term the spagyric process.
This special spagyric process makes our extracts incredibly bioavailable and nutritive, as well as ensuring that they are the widest-spectrum CBD-enriched extracts on the market today. We believe that by mimicking the natural biochemistry of the plant as closely as possible and processing gently, we can preserve all of the valuable therapeutic constituents.
We base this alchemical practice on internal experimentation and peer-reviewed literature published by reputable scientists and institutions. If you would like to read the original sources for the information we provided here, they may be found here: (source material coming soon).
*To read more about why we believe this is so important to creating an effective and truly whole-plant product, please feel free to read our pages on The Entourage Effectand Cannabinoids.


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