It's honestly more of a hassle, more expensive to set up and probably more efficient on flower if you use a vaporizer. No smoke means cooler temp no stains, the effect might be different but vapor is likely taking the best part and leaving the rest. Instead of making concentrate pens and processing up front you can use flowers with a volcano but they are expensive and cumbersome. Though it's fair to say there is less difference when you are smoking or vaping high grade. Some kind of water chilled or even humidified concentrate is best because lower allergies lower impurities try to reduce any potential negative side effect from ingestion.