Nicotinia Rustica, also known as "Wild Tobacco" has a nicotine content that is roughly 3x stronger in percentage then the typical Nicotinia Tobaccum (Common Tobacco) and it is only grown in the agricultural production settings for pesticide use and applications once its processed.
Pretty easy to grow and most insects are going to avoid the plant, especially if it is eaten. Aphids though, well they are a tobacco farmers nemesis due to their fondness for the tobacco stalks juices. They don't really harm the plant in small numbers, but the secretions that ants collect while farming them tends to develop black sooty looking mold almost overnight. In short, I keep wild tobacco in all of my gardens outside and I rarely have any problems with pests other than the Aphids mentioned which if caught earlier in the infestation are easily dealt with using a garden hose and a little Tanglefoot or even Vaseline.
Manidoo Seeds - Capturing the Spirit of Star Plants from around the world in Spirit Seeds bringing medicine to the people.