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Old 09-01-2016, 07:13 PM #201
oldchuck
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A fragrant grave - revealing the mummified remains of a 17th-century bishop
World Archaeology · March 2016
Per Lagerås
Bishop Peder Winstrup died in December 1679, aged 74, and was buried beneath Lund Cathedral. When, in 2014, it was decided that his coffin should be removed from
the crypt, a team of archaeologists took the opportunity to look inside. What they discovered surprised everyone: his clothes, his skin, and his hair were so perfectly preserved that he looked almost as if he were sleeping rather than having been dead for more than three centuries. But another shock awaited the team: the bishop was not alone. Secreted at his feet was the tiny body of a human foetus, probably a still-born baby. Winstrup and the baby lay on a bed of well-preserved plants, its pillows stuffed with herbs. Could these be the reason the remains looked so fresh? An interdisciplinary research team, directed by Per Karsten, Historical Museum at Lund University, was rapidly assembled to investigate.
Ah, Sam, you have an interest in archeology. So do I.
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Old 09-01-2016, 07:34 PM #202
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One of my real interest is Cannabis related archeology, but I have wide ranging Cannabis interests, I love Cannabis and everything related to it. Hemp, Medical, Religious, Recreational. And science like with the DNA work.
-SamS



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Ah, Sam, you have an interest in archeology. So do I.

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Old 09-01-2016, 07:44 PM #203
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thanks, thanks a lot for you have shared here.
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Old 09-03-2016, 08:28 PM #204
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Not so recent. But great for the history.
I will post a few more that are important for the history of Cannabinoid chemistry. They can be harder to find some are up to 100 years old, first try sci-hub.cc it has most of them, or google and see if online elsewhere.
-SamS


XL.- Charas. The Resin of Indian Hemp. T. BARLOW WOOD M. A.
W. T. NEWTON SPIVEY, M. A., and THOMAS HILL EASTERFIELD . M.A., P h . D .
J. Chem. Soc., Trans., 1896,69, 539-546
DOI: 10.1039/CT8966900539


III.—Cannabinol. Part I
Thomas Barlow Wood, M.A., W. T. Newton Spivey, M.A. and Thomas Hill Easterfield, M.A., Ph.D.
J. Chem. Soc., Trans., 1899,75, 20-36
DOI: 10.1039/CT8997500020
IN a paper communicated to the Society in 1896 (Trans., 1896, 88, 539) the authors, under the name of “cannabinol,” described a physiologically active substance which they had isolated from ‘ charas,” the exuded resin of Indian hemp. From the constancy ofcomposition of a number of preparations of this substance obtained from different samples of “charas,” it was believed to be a definite chemical compound of the formula C18H,,02 ; this conclusion seemed
to be justified by the determination of the molecular weight, and by the examination of several derivatives. Since then, the authors have further examined cannabinol, and have found that it is a mixture of at least two compounds having similar physical characters. One of these, of the formula C21H2602, has been isolated, and it is proposed to
retain the name cannabinol for this compound.

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Old 09-03-2016, 08:38 PM #205
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XIV. THE ACTIVE PRINCIPLES OF CANNABIS INDICA RESIN. I
BY THOMAS SPENCE WORK, FRANZ BERGEL AND ALEXANDER ROBERTUS TODD
Biochem J. 1939 Jan; 33(1): 123–127.
THE resinous exudate of the female flowers of Cannabis indica (C. sativa) forms the essential constituent of the drug variously known as hashish, bhang, charas, ganja and marihuana according to the country of origin and mode of pre- paration. Extracts of the flowers have been used in European medicine to some extent but were found to be so variable in activity that C. indica has been removed from the British Pharmacopoeia. The plant is, however, well known through its use as a drug in oriental countrie s and recently, under the name of "marihuana", its use has assumed dangerous proportions in America. Cannabis resin has been the subject of many investigations in the past but much of the earlier work is contradictory. The active principle is contained in a high-boiling resin and is not an alkaloid [Smith, 1857]. The active fraction isolated from the crude resin by Wood Spivey & Easterfield [1896] and given by them the name cannabinol was later found by the same workers [1899]to be a mixture, and the name cannabinol wast ransferred to that portion of the active resin yielding acrystalline acetate,M.P.75°. A good deal of confusion was introduced by later workers, who, although failing to obtain a crystalline acetate, nevertheless applied the name cannabinol to their products. The situation was largely clarified by Cahn [1931], who confirmed the observations of Wood Spivey & Easterfield and established for cannabinol the formula C21H2,O2.The con- stitution of cannabinol has been investigated by Cahn [1930-33] and by Bergel [1932], and for it the former proposed structure (I) in which only the positions of the hydroxyl and n-amyl groups are to be regarded as uncertain.
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Old 09-04-2016, 11:48 AM #206
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Isolation, structure and partial synthesis of an active constituent of hashish.
Journal of the American Chemical Society 86 (8): 1646–1647. Gaoni Y, Mechoulam R (1964).
Hashish (marihuana) ~ the psychotomimetically active resin of the female flowering tops of Cannabis sativa L. is one of the most widely used illicit narcotic drugs. A number of groups have reported the isolation of active constituents.2 Most of these substances are not fully characterized, and comparisons with or between them are difficult.
doi: 10.1021/ja01062a046

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Old 09-04-2016, 12:26 PM #207
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On the preparations of the Indian hemp (Cannabis indica); their effects on the animal system in health, and their utility in the treatment of tetanus and other convulsive diseases.
Transactions of the Medical and Physical Society, Bengal 71– 102, 421–426 (1843) O’Shaughnessy, W.B.
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Old 09-06-2016, 11:57 AM #208
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Science. 1940 Jun 21;91(2373):602-3.
A PHYSIOLOGICALLY ACTIVE PRINCIPLE FROM CANNABIS SATIVA (MARIHUANA).
Haagen-Smit AJ, Wawra CZ, Koepfli JB, Alles GA, Feigen GA, Prater AN.
DOI: 10.1126/science.91.2373.602
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Old 09-06-2016, 12:07 PM #209
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A brief history of cannabinoid and endocannabinoid pharmacology as inspired by the work of British scientists
TRENDS in Pharmacological Sciences Vol.27 No.3 March 2006
Vincenzo Di Marzo 2006
DOI: 10.1016/j.tips.2006.01.010
British scientists have played a leading role in the long history of cannabinoid and endocannabinoid research. Such research has progressed from the first crucial evaluation of the medicinal properties of Cannabis sativa in the Western world to pioneering studies of the chemical constituents of this plant, the development of in vitro biological assays to study cannabinoids, the identification of the mechanism of action of cannabinoids, the discovery of endocannabinoids and the assessment of their therapeutic implications. Stemming from the many innovative ideas and achievements of these researchers, I provide a personal view of where these studies have led us thus far and where they are
likely to take us in the future.
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Old 09-06-2016, 12:14 PM #210
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A historical overview of chemical research on cannabinoids
Raphael Mechoulam , Lumı´r Hanus
Chemistry and Physics of Lipids
108 (2000) 1–13
The chemical research on the plant cannabinoids and their derivatives over two centuries is concisely reviewed. The
tortuous path leading to the discovery of the endogenous cannabinoids is described. Future directions, which will
probably be followed are delineated.
doi: 10.1016/S0009-3084(00)00184-5

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