Lipids are dissolved to access the trichome insides, so even with subzero extraction dewaxing is sort of inevitable if you soak at those temps for long enough and you have a filter somewhere in there. I think, and this may be what you intended to ask, that it would be more productive to test a subzero extraction against a winterized extract for the remaining lipid fractions.
It's probably very hard to accomplish in any closed loop. Physically the easiest way is to do aluminum tubes in the subzero freezer with the butane. Wouldn't blast frozen glass...Don't think glass should be used in any extraction fwiw. No pressure issues, no issues with moisture in the final product, ect. I never really enjoy dabbing trim runs but fresh frozen I actually enjoy. It absolutely has to be below the freezing point of everything in the tube, specifically the water or else you will get moisture and will mostly likely cloud up the product during vac.
There are a couple types of waxes involved, one generally protecting the plant leaves, stems, and other surfaces, to help retain moisture.
There is also a wax coating the trichomes, that has some molecular differences, in that the molecules are hydrophobic on one side and hydrophylic on the side facing the trichomes.
We must dissolve them to get to the trichomes, but we don't have to take all of the waxes coating the rest of the plant as well.
We've winterized -50C extractions, and did remove some wax, but a small fraction of that with an ambient extraction.