-
Happy Birthday ICMag! Been 20 years since Gypsy Nirvana created the forum! We are celebrating with a 4/20 Giveaway and by launching a new Patreon tier called "420club". You can read more here.
-
Important notice: ICMag's T.O.U. has been updated. Please review it here. For your convenience, it is also available in the main forum menu, under 'Quick Links"!
Pure ZHO extraction solvent
- Thread starter SkyHighLer
- Start date
The cannabis testing labs are reporting trace residuals of chemicals that have near ambient boiling points such as pentane, but when I boil off a can of butane for a test I'm not seeing a puddle of pentane etc. towards the end, everything just boils off full tilt until there's just the nonvolatile Mystery Oil.
I'm not a chemical engineer, but I did have a full four year Merit scholarship to study Pharmacology at my choice of USC or Stanford back in the 70's... Looking back I'm glad I choose the path of herb instead of trying to cook up something new in the lab... ;-)
I need to wait for the experts to weigh in. Hopefully in next week, after initial test, then actual side by side comparisons.
Here are the lab results.
At the parts per billionth level, there are the usual green alligators and long necked geese, but for all practical purposes, the compounds at high enough levels to be of concern are Dimethylether and CO2.
Neither are particularly toxic but aren't listed in the Guidance for Industry from U.S. Department of Health and Human Services,
Food and Drug Administration Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER)
http://www.fda.govdownloadsDrugsGuidanceComplianceRegulatoryInformation/Guidances/ucm073395.pdf.
Here is a MSDS:
http://www.mesagas.com/images/Dimethyl Ether.pdf
Showing:
11. TOXICOLOGICAL INFORMATION
TOXICITY DATA: The following information is for Dimethyl Ether:
LC50 (inhalation, rat) = 164,000 ppm/4H
LC50 (inhalation, rat) = 308 g/m3
TCLo (inhalation, rat) = 2 ppb/6 hours/30 weeks-intermittent
Probable LD (oral, human) = 0.5-5 g/kg
11. TOXICOLOGICAL INFORMATION
TOXICITY DATA:
ACUTE INHALATION EFFECTS/ CHRONIC INHALATION EFFECTS FOR ANIMALS: Toxicity demonstrated in animals exposed by inhalation for short-term exposures include anesthetic effects, and depression of arterial blood pressure. Cardiac sensitization occurred in dogs exposed to concentrations of 20% in air and greater.
Toxicity experienced in animals from repeated exposure by inhalation include changes in white blood cell counts, anesthetic effects, increase in relative body/organ weight ratios for liver, spleen and testes and weight-gain suppression.
Toxicity demonstrated in rats upon log-term, repeated exposure at 200, 2000, 20000 ppm by inhalation include liver-weight reduction, and alterations of liver enzymes level in the high group.
In a different study in which rats were exposed to concentrations of 2000, 10000, or 25000 ppm observations include decreased red blood cell counts, spleen changes, decreased survival of males at the two higher exposure levels and hemolytic effects at 25,000 ppm.
Tests in animals demonstrate no carcinogenic or developmental toxicity.
EYE IRRITATION: No studies available for Dimethyl Ether.
SUSPECTED CANCER AGENT: Dimethyl Ether is not found on the following lists: FEDERAL OSHA Z LIST, NTP, IARC, CAL/OSHA, and therefore is neither considered to be nor suspected to be a cancer-causing agent by these agencies.
Tests in animals demonstrate no carcinogenic toxicity.
IRRITANCY OF PRODUCT: Dimethyl Ether is not irritating; however, contact with rapidly expanding gases can cause
frostbite to exposed tissue.
SENSITIZATION TO THE PRODUCT: Dimethyl Ether is not known to cause sensitization in humans. Cardiac sensitization has been noted in clinical studies involving test animals exposed to relatively high doses of Dimethyl Ether.
REPRODUCTIVE TOXICITY INFORMATION: Listed below is information concerning the effects of Dimethyl Ether on the
human reproductive system.
Mutagenicity: No human mutagenicity effects have been described for Dimethyl Ether. Dimethyl Ether does not produce genetic damage in bacterial cell cultures but has not been tested in animals.
Embryotoxicity: No embryotoxic effects have been described for Dimethyl Ether.
Teratogenicity: No human teratogenicity effects have been described for Dimethyl Ether.
Reproductive Toxicity: No human reproductive toxicity effects have been described for Dimethyl Ether. Tests in animals
demonstrate no developmental toxicity.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: Individuals with pre-existing diseases of the central nervous system or cardiovascular system may have increased susceptibility to exposures to Dimethyl Ether.
As there were no evil spirits found, we will proceed with extraction and testing.
At the parts per billionth level, there are the usual green alligators and long necked geese, but for all practical purposes, the compounds at high enough levels to be of concern are Dimethylether and CO2.
Neither are particularly toxic but aren't listed in the Guidance for Industry from U.S. Department of Health and Human Services,
Food and Drug Administration Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER)
http://www.fda.govdownloadsDrugsGuidanceComplianceRegulatoryInformation/Guidances/ucm073395.pdf.
Here is a MSDS:
http://www.mesagas.com/images/Dimethyl Ether.pdf
Showing:
11. TOXICOLOGICAL INFORMATION
TOXICITY DATA: The following information is for Dimethyl Ether:
LC50 (inhalation, rat) = 164,000 ppm/4H
LC50 (inhalation, rat) = 308 g/m3
TCLo (inhalation, rat) = 2 ppb/6 hours/30 weeks-intermittent
Probable LD (oral, human) = 0.5-5 g/kg
11. TOXICOLOGICAL INFORMATION
TOXICITY DATA:
ACUTE INHALATION EFFECTS/ CHRONIC INHALATION EFFECTS FOR ANIMALS: Toxicity demonstrated in animals exposed by inhalation for short-term exposures include anesthetic effects, and depression of arterial blood pressure. Cardiac sensitization occurred in dogs exposed to concentrations of 20% in air and greater.
Toxicity experienced in animals from repeated exposure by inhalation include changes in white blood cell counts, anesthetic effects, increase in relative body/organ weight ratios for liver, spleen and testes and weight-gain suppression.
Toxicity demonstrated in rats upon log-term, repeated exposure at 200, 2000, 20000 ppm by inhalation include liver-weight reduction, and alterations of liver enzymes level in the high group.
In a different study in which rats were exposed to concentrations of 2000, 10000, or 25000 ppm observations include decreased red blood cell counts, spleen changes, decreased survival of males at the two higher exposure levels and hemolytic effects at 25,000 ppm.
Tests in animals demonstrate no carcinogenic or developmental toxicity.
EYE IRRITATION: No studies available for Dimethyl Ether.
SUSPECTED CANCER AGENT: Dimethyl Ether is not found on the following lists: FEDERAL OSHA Z LIST, NTP, IARC, CAL/OSHA, and therefore is neither considered to be nor suspected to be a cancer-causing agent by these agencies.
Tests in animals demonstrate no carcinogenic toxicity.
IRRITANCY OF PRODUCT: Dimethyl Ether is not irritating; however, contact with rapidly expanding gases can cause
frostbite to exposed tissue.
SENSITIZATION TO THE PRODUCT: Dimethyl Ether is not known to cause sensitization in humans. Cardiac sensitization has been noted in clinical studies involving test animals exposed to relatively high doses of Dimethyl Ether.
REPRODUCTIVE TOXICITY INFORMATION: Listed below is information concerning the effects of Dimethyl Ether on the
human reproductive system.
Mutagenicity: No human mutagenicity effects have been described for Dimethyl Ether. Dimethyl Ether does not produce genetic damage in bacterial cell cultures but has not been tested in animals.
Embryotoxicity: No embryotoxic effects have been described for Dimethyl Ether.
Teratogenicity: No human teratogenicity effects have been described for Dimethyl Ether.
Reproductive Toxicity: No human reproductive toxicity effects have been described for Dimethyl Ether. Tests in animals
demonstrate no developmental toxicity.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: Individuals with pre-existing diseases of the central nervous system or cardiovascular system may have increased susceptibility to exposures to Dimethyl Ether.
As there were no evil spirits found, we will proceed with extraction and testing.
Attachments
JointOperation
Active member
so its safe? and can i ask... gray wolf i know your the man of extracts lol.. great site u got .. so much info.. love it all..
so what are you conclusions as to .. is this a safer product for people to use without vacuum chambers.. or is butane safer without a vacuum chamber? ..
with a chamber are they both the same .. safety wise?
so what are you conclusions as to .. is this a safer product for people to use without vacuum chambers.. or is butane safer without a vacuum chamber? ..
with a chamber are they both the same .. safety wise?
Either lends itself to vacuum reclaim, but not sure about things like pump and valve seals yet for Dimethyl ether and still checking.
Both have a boiling point significantly below ambient, so will be rapidly vaporizing in open air at ambient temperatures.
Both are highly flammable, and require a high level of attention to detail to safely extract using open extraction systems.
As for toxicity, I see nothing in the analysis that will stop me from sampling the extract I will make using it, but I do plan to use the same vacuum purging techniques that I use for BHO.
Both have a boiling point significantly below ambient, so will be rapidly vaporizing in open air at ambient temperatures.
Both are highly flammable, and require a high level of attention to detail to safely extract using open extraction systems.
As for toxicity, I see nothing in the analysis that will stop me from sampling the extract I will make using it, but I do plan to use the same vacuum purging techniques that I use for BHO.
SteelyMcKush
Member
We had two bags of grass, seventy-five pellets of mescaline, five sheets of high-powered blotter acid, a saltshaker half-full of cocaine, and a whole galaxy of multi-colored uppers, downers, screamers, laughers... Also, a quart of tequila, a quart of rum, a case of beer, a pint of raw ether, and two dozen amyls. Not that we needed all that for the trip, but once you get locked into a serious drug collection, the tendency is to push it as far as you can. The only thing that really worried me was the ether. There is nothing in the world more helpless and irresponsible and depraved than a man in the depths of an ether binge, and I knew we'd get into that rotten stuff pretty soon.
Fear and loathing in Las Vegas.
Fear and loathing in Las Vegas.
MZ12X.
Dr Z hasn't sent me any pure zho for testing, but if they will do so, I will certainly get it tested as well.
Thank you Dr Z for cutting to the chase and supplying the MZ12X samples!
SteelyMcKush
Member
Thanks, I was a little confused there.
Really looking forward to seeing how your extraction goes with it GW, Good luck.
Thanks GW, pm me the bill. 
)
You're welcome Doctor Z... ;-)
)You're welcome Doctor Z... ;-)
Off to buy a case right now, ill post back my results later tonight. Any tips for extraction?? Going to running open tube since i dont have a storage tank i can use for passive recovery. Should i freeze my tube first or anything??? I heard there's alot of pressure in these cans, should i be worried with a glass tube?
I doubt it'll take your glass tube down lower than about -20F before settling in at the BP of about -12F. Wasn't a problem for the Mason jar I shot it into...
I'd freeze everything.
If it leaks down the tube onto your bare hand you won't be able to hold onto the tube...the freezing cold is that excruciatingly painful. Polar Penguin ice fishing gloves are cheap, I purchased mine through ebay because they had a choice of sizes.
I'm expecting it to extract harder/faster, with hopefully a beautiful terpene profile. At the current price, it's main market is probably for closed loop extractions and the curious.
In the vacuum now, sitting around 90F. Looks nice, good color, has a nice smell. Ill pst some pics soon. I froze the can and tube for an hour, i was impatient lol. Ill freeze another tube and can tonight all night and see if that has any effect on color or anything. Yup i wrapped a towel around the tube, and used leather driving gloves. Unfortunately i have no access to testing labs so someone else will have to do that. I do have very sensitive lungs/throat and can usually tell if oil hasn't been purged right
SteelyMcKush
Member
When can we expect to hear about your trial runs with it SkyHighler?
Mz12X First impressions
Mz12X First impressions
Packed 36 grams of REALLY good sugar trim into a 1" ID ~6" long glass tube. Into a 6x8 pryex in some 100F hot water after i was done spraying. Used about 75% of one 500ml can, took around 10 minutes to evaporate enough off to bring inside. Use a heat gun to help in a 90F hot water bath for 15 minutes maybe.
Scraped it up & Threw it on parchment... BAD idea lol silicone is a D rating compatibility... going to use a piece of glass next time. Damn habits, wasn't much solvent left when i put it on the parchment so its probably fine but best option would be glass.
From there it went in a 8" desiccator on a couple hot ceramic tiles at 110-90F. I would take it out rotate tiles with fresh hot tiles and use the heat gun and flip the little slab over a few times every 10 minutes or so for about 40-60 minutes i think.
Soft shatter constancy, could probably go in an oven for longer but my oven and mkIII are being used at the moment at a friends farm, and im lazy so it only purged until there were no more bubbles forming at full vac. Pretty good stuff for using what i had laying around and open blast. Taste is good, pretty smooth, ill give more feedback ass i try it more.
My yield was only 12% returning 4.5 grams.. Ehh not the greatest, the last round i ran this strain the trim kicked back 18% ran using -20F butane in a mkIII no heat poured out method. But it was a wide glass tube and open so its not horrible i guess.
Open tubes suck...
Mz12X First impressions
Packed 36 grams of REALLY good sugar trim into a 1" ID ~6" long glass tube. Into a 6x8 pryex in some 100F hot water after i was done spraying. Used about 75% of one 500ml can, took around 10 minutes to evaporate enough off to bring inside. Use a heat gun to help in a 90F hot water bath for 15 minutes maybe.
Scraped it up & Threw it on parchment... BAD idea lol silicone is a D rating compatibility... going to use a piece of glass next time. Damn habits, wasn't much solvent left when i put it on the parchment so its probably fine but best option would be glass.
From there it went in a 8" desiccator on a couple hot ceramic tiles at 110-90F. I would take it out rotate tiles with fresh hot tiles and use the heat gun and flip the little slab over a few times every 10 minutes or so for about 40-60 minutes i think.
Soft shatter constancy, could probably go in an oven for longer but my oven and mkIII are being used at the moment at a friends farm, and im lazy so it only purged until there were no more bubbles forming at full vac. Pretty good stuff for using what i had laying around and open blast. Taste is good, pretty smooth, ill give more feedback ass i try it more.
My yield was only 12% returning 4.5 grams.. Ehh not the greatest, the last round i ran this strain the trim kicked back 18% ran using -20F butane in a mkIII no heat poured out method. But it was a wide glass tube and open so its not horrible i guess.
Open tubes suck...
Attachments
