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Marijuana Cannabinoids Found to Help Combat Autism

Bi0hazard

Active member
Veteran
Marijuana Cannabinoids Found to Help Combat Autism

Look at the Swag they posted up as a picture. Is that really the only cannabis pictures they have on file?

Full Article @ http://au.ibtimes.com/articles/3920...ids-found-help-combat-autism.htm#.UIFeD8hmMcc

"The cannabinoid compounds naturally found in many varieties of cannabis, also known more commonly as marijuana, may help children with autism spectrum disorders experience dramatic behavioral improvements, and potentially even full recovery from their symptoms. These are the findings of a new study published in the journal Nature Communications that help reinforce the growing body of evidence which shows that medicinal cannabinoids hold incredible potential in both treating and potentially curing chronic illness.

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Daniele Piomelli from the University of California, Irvine (UCI) and her colleague Olivier Manzoni from Inserm, a French research agency, observed that marijuana cannabinoids are very closely related to the endocannabinoid transmitters naturally found in the brain that facilitate the transport of electrical signals between neurons. Known as 2-AG, these transmitters are responsible for regulating a whole host of important bodily processes, which include things like telling the body when it is hungry or when it is experiencing pain.

Children with autism spectrum disorders; however, including those who developed these disorders as a result of Fragile X syndrome, which is said to be the most commonly-known genetic cause of autism, often have poorly or non-functioning 2-AG, which necessitates chronic synaptic failure in the brain. Many children with Fragile X-induced autism end up becoming mentally disabled as a result of this synaptic failure, and have trouble developing basic motor skills like walking and talking, or learning how to behave in various social situations.

But taking marijuana cannabinoids, which as we pointed out in an earlier article are not psychoactive in the same way that tetrahydrocannabinol (THC) is (http://www.naturalnews.com/035759_cannabis_juicing_health.html), can help effectively block the enzymes that inhibit the proper function of 2-AG. In essence, marijuana cannabinoids essentially restore synaptic communication by feeding an ailing body the cannabinoids it lacks, which are absolutely vital for proper cell function and communication.

"Endocannabinoid compounds are created naturally in the body and share a similar chemical structure with THC ... (and) are distinctive because they link with protein molecule receptors -- called cannabinoid receptors -- on the surface of cells," explains the UCI report. "Because the body's natural cannabinoids control a variety of factors -- such as pain, mood and appetite -- they're attractive targets for drug discovery and development."
Can non-psychoactive cannabinoid compounds actually cure chronic illness?

Though the researchers were quick to deny that cannabinoids hold any potential at actually curing autism, which more than likely was a politically-motivated denial rather than a factual admission, other research and actual case studies suggest that cannabinoid compounds are, indeed, powerful enough to mitigate many or all of the symptoms associated with autism, as well as many other diseases.
"Sam's Story," for instance, explains how one young boy with severe autism symptoms experienced dramatic improvements as a result of his parents giving him medical cannabis (http://www.letfreedomgrow.com/cmu/SamsStory.htm). Another young boy named Joey has also responded incredibly well to treatments with medical cannabis which, unlike pharmaceutical drugs, does not elicit any harmful side effects. (AutismNews/mother-son-marijuana-treat-autism/story?id=9153881" target="_blank">http://abcnews.go.com)

The group Cannabis International has also been conducting extensive research into medical marijuana, and particularly the non-psychoactive cannabinoid compounds found abundantly in many cannabis strains that have exhibited powerful benefits in treating autoimmune disorders, chronic inflammatory conditions, cellular and neurological dysfunction, and cancer, among others: http://www.naturalnews.com/035759_cannabis_juicing_health.html

Learn more: http://www.naturalnews.com/037445_marijuana_cannabinoids_autism.html#ixzz28hR5aEo1
 
S

SeaMaiden

Wow. I'm waiting for the definitive paper on cannabinoids and Tourette's, too.

Thank you.
 
That's great research one day the powers that be will have to acknowledge the many benefits of this great plant it is also much better for ADD than any of the current drugs.
 

jayjayfrank

Member
Veteran
really hate to do this, but i would love to think that cannabis cures all kinds of crap but some of the links on that site looked shady.

"Most Popular Stories
Colorado Batman shooting shows obvious signs of being staged"


but i found something a little more reassuring - the actual article http://www.nature.com/ncomms/journal/v3/n9/full/ncomms2045.html

which is comforting because i have actually heard of the journal "Nature" before.


also some of the comments got the wheels turning
"Although cannibinoids may impact symptomology, it is unwise to think that the person with autism would be "cured." Autism is a pervasive brain difference expressed in multiple brain structures, regions, and functions."

just an idea, a crazy theory, couldn't be true but just saying. what if its not smoking weed that caused autism. like going generations of not having whatever THC does to your endocannabinoid system lets autism take a 'foothold' - these combined with other factors (sterile delivery rooms/vaccines/diet) in varying degrees amount to the spectrum of autism. anecdotal evidence for why also some claim to 'cure' it through diet or non-vaccination.

another one of the reasons there should be massive efforts for pharmaceutical cannabis research.
 

Bi0hazard

Active member
Veteran
AUTISM

Consequences of cannabinoid and monoaminergic system disruption in a mouse model of autism spectrum disorders. (abst – 2011) http://www.ncbi.nlm....pubmed/21886592

Use of dronabinol (delta-9-THC) in autism: A prospective single-case-study with an early infantile autistic child (full – 2010) http://www.cannabis-...n_2010_04_1.pdf

Variation in the human Cannabinoid Receptor (CNR1) gene modulates gaze duration for happy faces. (full – 2011) http://www.molecular...0-2392-2-10.pdf

Can autism be triggered by acetaminophen activation of the endocannabinoid system?
(link to full – 2010) http://www.ane.pl/sh...le.php?art=7026

THE SAM PROJECT: James D. (news / anecdotal - 2002)
http://www.letfreedo...les/james_d.htm

Medical marijuana: a valuable treatment for autism? (news / anecdotal - 2003)
http://www.autism.co...d_marijuana.htm

Variations in the human cannabinoid receptor (CNR1) gene modulate striatal responses to happy faces. (abst – 2006) http://www.ncbi.nlm....pubmed/16623851

Autism, ADD, ADHD and Marijuana Therapy (news - 2008)
http://www.entheolog...iewer.asp?a=319

Does marijuana replace pharmaceuticals as a treatment for Autism? (news – 2009)
http://www.examiner....ment-for-autism

Sam‘s Story: Using Medical Cannabis to Treat Autism Spectrum Disorder
(news / anecdotal - 2009) http://www.letfreedo...u/SamsStory.htm

Mom: Medical marijuana saved son's life (news / anecdotal - 2009)
http://abclocal.go.c...alth&id=6989085

The ultimate herbal remedy: Can cannabis improve autism? (news / anecdotal - 2009)
http://www.independe...sm-1814756.html

Sam's Story: Medical Marijuana and Autism (news / anecdotal - 2009)
http://www.ktla.com/...0,1396115.story

Steamboat mom sees results from giving autistic son medical marijuana
(news/ anecdotal - 2010)
http://www.steamboat...tistic-son-med/

Why I Give My Autistic Son Pot, Part1 (news – 2010)
http://www.doublex.c...-9-year-old-pot

Why I Give My Autistic Son Pot, Part2 (news – 2010)
http://www.doublex.c...old-pot-part-ii

Why I Give My 9-Year-Old Pot, Part 3 (news - 2010) http://www.slate.com/id/2251174/

Cannabis Science And The Unconventional Foundation For Autism (UF4A) Partner To Advance Successful Cannabis-Based Autism Treatments (news/info-mercial - 2011)
http://www.medicalne...ases/219569.php

Why I Give My Autistic Son Pot, Part 4 (news – 2011) http://www.slate.com...94072/?from=rss

Wayne Valley alum making a difference in autism research (news – 2011)
http://www.northjers...m_research.html
 
S

SeaMaiden

I won't say, because I can't say it cures autism, but I feel it mitigates the effects very well/strongly. Especially certain stemming behaviors and, just as importantly for many, helps with appetite and intestinal issues that so many austistics suffer chronically, such as IBS/Chrohn's (sp?).

I also have direct experience with a Touretter and cannabis and can measurably demonstrate that once the cannabinoids enter the system, his tics disappear. Completely. It's fascinating, and I wish I'd known long ago.
 
I won't say, because I can't say it cures autism, but I feel it mitigates the effects very well/strongly. Especially certain stemming behaviors and, just as importantly for many, helps with appetite and intestinal issues that so many austistics suffer chronically, such as IBS/Chrohn's (sp?).

I also have direct experience with a Touretter and cannabis and can measurably demonstrate that once the cannabinoids enter the system, his tics disappear. Completely. It's fascinating, and I wish I'd known long ago.


That is VERY interesting information. It would be nice to know what form of autism has been declared and how cannabis effects that specific classification. Regarding the Tourette syndrome, It`s usually something that effects children and those under the age of 18 years. It can persist into adulthood and this can be very problematic for the quality of life.

Cannabis has been proven to effect the memory. ~ (although I have no problem remembering more than 200 numbers in 10 minutes and reciting them 10 minutes later.)

http://www.academia.edu/243769/The_chronic_effects_of_cannabis_on_memory_in_humans_a_review

It COULD be the cannabis can change the "TIC`S" of a person suffering from Tourette`s syndrome by forcing the brain to "forget" the TIC`s. any information you have will be great. :)
 

Bi0hazard

Active member
Veteran
Stondestmanaliv,

Strains with high THC with low CBD can create some short term memory issues, especially in people with low tolerances. However, strains that have CBD, prevent memory issues. The cannabinoids protect each other and help balance out side effects that the others create.

Smoke strains higher in CBD during the week, and even times when you are just smoking high THC strains, your memory will be better.

Abstract Results:
Groups did not differ in the THC content of the cannabis they smoked. Unlike the marked impairment in prose recall of individuals who smoked cannabis low in cannabidiol (CBD), participants smoking cannabis high in cannabidiol (CBD) showed no memory impairment.
 
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Bi0hazard

Active member
Veteran
Impact of CBD (Cannabidiol) on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study (2010)
Full Primary Article @ http://bjp.rcpsych.org/content/197/4/285.full.pdf


The medical cannabis movement needs to be country wide, and we need to move towards full legalization ASAP; to prevent the fed from attacking the states for medical use (claiming that anything under schedule 1 has no medical value). If it was legal, they would no longer have their bull shit grounds to stand on in harassing medical patients and growers country wide.

Found a really interesting article on how strains with higher amounts of CBD - remove any memory issues associated with cannabis use. They found strains high in THC with very little to no CDB were the culprit for the memory issues and that high CBD rates not only removed any short term memory issues - but also help rebuild brain networks (Neuron genesis) for diseases where brain damage or memory loss is an issue - like Alzheimer's for example. Really interesting and good info to know =]

Seriously, the Endocannabinoid (Natural cannabinoid) system in our body is one of the most interesting things - they have found out in the past 15 years that it is involved in the regulation of 70% of our body in one way or another. From regulating Leptin (Our bodies metabolism), regulating inflammation, releasing the high associated with eating chocolate (Anandamide), or most of the runner's high from working out (it used to believe it was mostly endorphins (natural opiates) but they found way more natural cannabinoids released during working out than endorphins. The natural cannabinoid system has been found to have a part in the natural regulation of hundreds of functions involving the body.

Full Primary Article @ http://bjp.rcpsych.org/content/197/4/285.full.pdf

Abstract Results:
Groups did not differ in the THC content of the cannabis they smoked. Unlike the marked impairment in prose recall of individuals who smoked cannabis low in cannabidiol (CBD), participants smoking cannabis high in cannabidiol (CBD) showed no memory impairment.

Conclusions (Abstract)
The antagonistic effects of cannabidiol (CBD) at the CB1 receptor are probably responsible for its profile in smoked cannabis, attenuating the memory-impairing effects of THC. In terms of harm reduction, users should be made aware of the higher risk of memory impairment associated with smoking low-cannabidiol strains of cannabis like ‘skunk’ and encouraged to use strains containing higher levels of cannabidiol.
 
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Bi0hazard

Active member
Veteran
Cannabinoids have also been shown in lab studies to Grow new Adult Neurons (New brain cells!) in the hippocampus. Which is the area of the brain involved in Learning and Memory:

Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects (2005)
Full Article: http://www.jci.org/articles/view/25509
 
S

SeaMaiden

Bi0, you're not kidding about the endocannabinoid system. We humans already use at least some phyto-genic (not sure if I've made that word up, plant-based medications is what I intend to convey) replacements when our bodies aren't making something that we need. Progesterone creams applied dermally or transvaginally, compounded from soy or a type of wild yam found in Mexico, are the first example I think of here. Progesterone is an incredibly strong hormone and body process regulator.

I have a paper to share with you about endocannabinoids. You've probably seen it.

http://www.ingentaconnect.com/content/ben/cpd/2000/00000006/00000013/art00006
 

Bi0hazard

Active member
Veteran
SeaMaiden,

I haven't read that one yet. Although I did start reading through a university book on the endocannabinoid system recently. It would be nice to see the full article. One of my favorites so far is this one, this great chart comes from this research: It doesn't cover THC, which has many incredible benefits, especially when mixed with the other cannabinoids. This article is very in depth though, about the other spectrum of cannabinoids.

Full Article: Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb (2009)

Full Article PDF @ http://www.onlinepot.org/medical/Izzo%20Plant%20Cannabinoids%20Therapeutic%20Opportunities%20TIPS%202009.pdf

picture.php
 
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