I err on the side of not pruning now after I pruned the bottom quarter of my last crop two weeks into flower, cost me 50% in yield
urine..diluted in water at 1:10 lol
i also think it depends on the strain,and how the buds form..some strains have huge,top colas,while some (og's,bubba kush,trainwreck) have alot of smallish round chunky buds,and theyr all viney and floppy,i think the latter would benefit from cutting off big fan leaves,
This is exactly what I do. Knowing when stretch is over is huge. 40% of the 12/12 cycle will be stretch.it all depends on how much time I have to veg. Any topping or de-leafing stresses and slows the growth so I'm careful not to cost myself a full canopy by the end of stretch.
If I have plenty of veg time, I absolutely do. I usually only top once when they are little. Then I aggressively defoliate once a week. This keeps the node spacing much tighter and helps control the plants growing into each other and causing even more stretch. It also pushes out tons more budsites.
Then at one week prior to flip, I take clones off the lower branches and prune off any suckers and low light branches. Then they recover for one week and the flip. Then I don't touch* until again till after stretch. After stretch I nip off any sucker branches that may have appeared and big fans that are shading. Then throughout the remainder of flower I only nip oversized fans.
*the only time that I will mess with them during stretch is if there are some shoots or tops that are getting outta control. For those I will supercrop (pinch) or defoliate the shoot to stunt it a little.