O'Shaugnessy's- Review of Russo's Terpenes and 'Entourage effect'

[Chimera]

http://cannabisclinicians.org/wp-content/uploads/2011/09/Russo-Entourage-Effect.pdf

There's been a few mentions of this article and the one from which this review was drawn, so I figure I'd post it so people could have a look for themselves.

Enjoy,
-Chimera

 

[draztik]

Cool info. Loving your GF X BB!!

 

[Ultra Current]

Nice article! Want to get a copy of that!

 

[Chimera]

You can order O'Shaugnessy's via mail order, it's a great piece of journalism focused on medicinal cannabis in California.

Contact Fred or Martin through projectcbd.org ... tell them Chimera sent you!

Project CBD
P.O. Box 260
Healdsburg, CA 95448
USA

Phone: +707 581 1818
eMail: info@ProjectCBD.org

 

[plastochron]

my boss was quoted in one of these articles. did you check out the lab ring test article from o'shaugnessy's a few months ago? what did you think? on another aside, have you done any breeding projects to produce a really chemically unique cultivar (e.g. high in CBDA, THCVA, any number or combo of terpenes)?

 

[hades]

Great article, thanks for the link. A few of the more notable parts are where he specifically mentions CBD as helping drug addiction and countering drowsiness.

 

[mr.brunch]

thank you for this info

 

[Green Supreme]

Great info. Thanks for sharing. Peace GS

 

[Payaso]

O’Shaughnessy’s is a most respected journal, and the information in the pdf presented by Chimera is fascinating, and apparently quite true.

My hat's off in respect to Fred Gardner for many reasons, but especially for continuing his work with O’Shaughnessy’s.

Thank you Chimera for posting this information!

 

[Dysnomia]

Great article!

I wonder why this hasn't got more attention though. From what I've read on the forums it seems that many people seem to associate the kind of high you get from the herb to the different ratios of cannabinoids, especially the THC:CBD ratio. According to the article however, it seems that when it comes to the specific nuances of the high, the terpenoids that are present seem to play quite a role. Especially so since most varieties nowadays are high in THC and low in CBD, but we still see quite a difference in effects.

For example lets take the terpenoid Myrcene. The article states that combined with THC it may produce the ‘couch-lock’ phenomenon of certain chemotypes.

Now since terpenoids are aromatic molecules and the ones responsible for the wide bouquet of aromas our favorite plant produces AND they play a role in the nuances of the high, would it be safe to say that the aroma of a specific plant plays a much bigger role than just 'wow, this smells nice'? But why stop here? The strength of the aroma should also relate to the amount of terpenoids present (I'm sure it's not really as simple as that, but for arguments' sake) and could therefore indicate how 'modified' the high would be.

Am I over-stating the 'value' of terpenoids, or does it only seem to me, that they have been greatly overlooked in the industry?


regards,
Dysnomia

 

[Fluffy Clouds]

I wonder why this hasn't got more attention though. From what I've read on the forums it seems that many people seem to associate the kind of high you get from the herb to the different ratios of cannabinoids, especially the THC:CBD ratio.

i dont wonder cause for most of people myths are more interesting than truth or real research... yes they are thinking that when some strain has more thc its better than strain with less thc what a joke! they like to translate quality to quantity its easier to count than to think...

 

[Nunsacred]

Great article!
.... the terpenoids that are present seem to play quite a role.

Now since terpenoids are aromatic molecules and the ones responsible for the wide bouquet of aromas our favorite plant produces AND they play a role in the nuances of the high, would it be safe to say that the aroma of a specific plant plays a much bigger role than just 'wow, this smells nice'? But why stop here? The strength of the aroma should also relate to the amount of terpenoids present (I'm sure it's not really as simple as that, but for arguments' sake) and could therefore indicate how 'modified' the high would be.

Am I over-stating the 'value' of terpenoids, or does it only seem to me, that they have been greatly overlooked in the industry?


regards,
Dysnomia

I think you're right to some extent.

Doesn't bubblehash have greatly reduced terpenes compared to dry sift? I expect someone's tried making both from the same plant and could tell us if there's a noticeable difference in hit between the two....

...anyone?

 

[atarijedi]

Makes me think of a quick shoddy experiment one can do.

Take 2 buds from the same plant, cure one normally and do a water cure on the other. Then do some various subjective tests to compare them, smell, taste, the feeling of the high etc...

I say water cure because most water cured bud I have had is notably less aromatic in both smell and taste. But I have never thought to do a high comparison.

 

[El Toker]

I think you're right to some extent.

Doesn't bubblehash have greatly reduced terpenes compared to dry sift? I expect someone's tried making both from the same plant and could tell us if there's a noticeable difference in hit between the two....

...anyone?

The hit seems to be much the same to me with bubble hash as it is with bud and I've never heard of anyone reporting otherwise. However, it still smells like bud and tastes of bud when you cook with it so I assume that the terpenes are still there to some extent as they are responsible for smell and taste.