oh hell no.....
have to start with a clean slate........
The system I use requires new coco (mix) each go around. Its not much though, as I use the 8" dia airpots (6 liter, I think). I use Botannicare's high aeration ReadyGro with a top drip to waste and it works a charm.
Been using a pond enzyme known a pond care barley clear, which uses peat/barley concentrated enzymes and so far its been working better than cannazyme.
I just cut around the stem and remove the big roots (pull them out) and i put about a fresh handful of preflushed unused coco ontop of the cut out so that the fresh clone has some new coco to grow into and then it can fight its way through the old coco which is saturated with roots. The above technique is done in 2 litre pots filled with coco only for the first 3 runs, after that, i remove the coco completely from the pot and sift through it removing any roots that i can and then repot the coco, 75 percent used, and 25 percent unused preflushed coco.
Before repotting a clone into used coco, i flush the coco with florakleen and Dutchmaster zone to get rid of any nasty salts and unwanted parasites, pathogens etc.
Above technique has served me well and the plants actually thrive much better in the 2nd and 3rd run when reusing the coco in the 2l pots.
Also found out, cause of the extra root mass in the coco, it retains alot more water and you need give atleast 1-2 days between watering until the roots have spread out through the coco, takes about 14 days in square 2l pots, the pots are then light everyday compared to every 2 - 3 days when first potting the clone.