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I don't use one for low pressure. I have misters running 24/7 and I think this offers the best oxygen/water ratio for hydroponic set-ups. On high pressure set-ups I'd say it's mandatory because such a fine mist dries out very quickly and a constant mist seems like it would suffocate the root system since the micron size of the water is much smaller.
It's not necessarily bad to run a high-pressure pump for more than a few seconds, it's just unnecessary. It only takes a few seconds at most to drench the roots. I personally run my high-pressure systems for a 1on/5off, and see no ill effects because of it.