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    Ok back to the subject at hand.

    Any Cancer Treatment patients in the house that are using concentrates? Methods? Outlook?

    You are all in our thoughts, Jah Blessed.

    LT
    LostTribe

    C99 The Ultimate Search and Rescue Mission
    https://www.icmag.com/ic/showthread.php?threadid=334331

    Treating Cancer with Concentrates
    https://www.icmag.com/ic/showthread.php?t=301121

    Comment


      Somebody was on here discussing his colon cancer treatments this week hope he keeps strong and fights through it!
      LostTribe

      C99 The Ultimate Search and Rescue Mission
      https://www.icmag.com/ic/showthread.php?threadid=334331

      Treating Cancer with Concentrates
      https://www.icmag.com/ic/showthread.php?t=301121

      Comment


        For the suppositories what are the recommended dosages? Are you guys infusing with coco oil or just straight concentrates?
        LostTribe

        C99 The Ultimate Search and Rescue Mission
        https://www.icmag.com/ic/showthread.php?threadid=334331

        Treating Cancer with Concentrates
        https://www.icmag.com/ic/showthread.php?t=301121

        Comment


          Originally posted by Gray Wolf View Post
          Ummm, 200 mg of cannabis absolute in a coco butter suppository certainly demonstrated THC effects when I personally tested it and the cancer patients we've made them for report effects as well.

          Hee, hee, hee, wait till I tell you where we all stuck them!
          So is the 200mg of absolute combined with coco oil what you would recommend for most cancer patients?
          LostTribe

          C99 The Ultimate Search and Rescue Mission
          https://www.icmag.com/ic/showthread.php?threadid=334331

          Treating Cancer with Concentrates
          https://www.icmag.com/ic/showthread.php?t=301121

          Comment


            If you are using suppositories I whould recommend olive oil over coco. It blends evenly and doesn't separate. And I would be afraid to go over 1:1
            Its a weed it will grow.

            Comment


              Originally posted by LostTribe View Post
              So is the 200mg of absolute combined with coco oil what you would recommend for most cancer patients?
              Coco butter. It is stiff enough to insert, where coconut oil is not.

              We worked our cancer patients up to 300 mg doses. I only tested the 200 mg.
              An age is called Dark not because the light fails to shine, but because people refuse to see it.

              Believing is seeing and ignorance is bliss until it bites you in the ass!

              Fervor is the weapon of the impotent. The harder the sell, the poorer the product.

              Alas, my ignorance abounds; the more I've learned, the less I know that I know..........

              Thou shalt seek and respect the opinions of operators, even unto the third helper, for theirs is a wisdom unknown to technicrats.

              Wise men learn more from fools, than fools from wise men.

              In my dotage I finally discovered that the secret to putting on pants both legs at a time is sitting down.


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              Comment


                Originally posted by Mednugs View Post
                If you are using suppositories I whould recommend olive oil over coco. It blends evenly and doesn't separate. And I would be afraid to go over 1:1
                Ummmm, how easy is it to insert? Maybe a little like shooting pool with a cotton rope for a cue?
                An age is called Dark not because the light fails to shine, but because people refuse to see it.

                Believing is seeing and ignorance is bliss until it bites you in the ass!

                Fervor is the weapon of the impotent. The harder the sell, the poorer the product.

                Alas, my ignorance abounds; the more I've learned, the less I know that I know..........

                Thou shalt seek and respect the opinions of operators, even unto the third helper, for theirs is a wisdom unknown to technicrats.

                Wise men learn more from fools, than fools from wise men.

                In my dotage I finally discovered that the secret to putting on pants both legs at a time is sitting down.


                https://graywolfslair.com/

                Comment


                  Originally posted by G.O. Joe View Post
                  It's an established scientific fact, whether it's true or not. The hemisuccinate ester is the usual suppository form of THC.
                  Does conversion to the ester make it more water soluble?

                  Would this same prodrug work orally or is it completely different mechanisms of absorption and metabolization?

                  Comment


                    Currently have a friend with pancreatic cancer w/ metastasis into liver, 2nd round of chemo. Made some oil using ethanol/rice cooker and 20 cc syringe. He felt it was too 'druggy' (his term) not being a cannabis user. We experimented with dose, but he didn't like the sensation orally.

                    Then, I made suppositories from the remaining oil (size 1#). He's taking 3x a day, larger dose at night (00#). Reports less pain, a bit more energy, ability to eat after chemo.

                    Made another batch finely ground herb heated in coconut oil, then cooled before filling capsules. He seems to tolerate that better, again, 3x a day (size 1# gel capsule) and 00# at night. Cannot accurately measure g/ml and mg, but ratios for ground herb into oil 3:1.5, similar to a paste.

                    Any added suggestions would be welcome.
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                    Comment


                      Originally posted by live resin View Post
                      Does conversion to the ester make it more water soluble?

                      Would this same prodrug work orally or is it completely different mechanisms of absorption and metabolization?
                      I assume it's easily hydrolyzed regardless - it can be injected as well - so measuring solubility could be a problem.
                      In the clinical field, the practical application of these substances must be awaited with the usual necessary patience. - Roger Adams
                      Marihuana
                      February 19, 1942

                      Comment


                        what are recommendations for taking concentrates orally for cancer? The same as for the suppositories?
                        LostTribe

                        C99 The Ultimate Search and Rescue Mission
                        https://www.icmag.com/ic/showthread.php?threadid=334331

                        Treating Cancer with Concentrates
                        https://www.icmag.com/ic/showthread.php?t=301121

                        Comment


                          Originally posted by aridbud View Post
                          Currently have a friend with pancreatic cancer w/ metastasis into liver, 2nd round of chemo. Made some oil using ethanol/rice cooker and 20 cc syringe. He felt it was too 'druggy' (his term) not being a cannabis user. We experimented with dose, but he didn't like the sensation orally.

                          Then, I made suppositories from the remaining oil (size 1#). He's taking 3x a day, larger dose at night (00#). Reports less pain, a bit more energy, ability to eat after chemo.

                          Made another batch finely ground herb heated in coconut oil, then cooled before filling capsules. He seems to tolerate that better, again, 3x a day (size 1# gel capsule) and 00# at night. Cannot accurately measure g/ml and mg, but ratios for ground herb into oil 3:1.5, similar to a paste.

                          Any added suggestions would be welcome.
                          We bought disposable suppository molds off the internet, and mixed warm coco butter and the dosage, blended them well, and poured them in the molds, before sticking them in the freezer to set.

                          When they cool down, they are solid enough at room temperature to insert, after the disposable mold is torn away. Coco butter way stiffer than coconut oil.

                          Here is a mold link as an example, but if you google suppository molds you will be offered a panoply of choices.

                          http://www.cureyourowncancer.org/suppository-molds.html
                          An age is called Dark not because the light fails to shine, but because people refuse to see it.

                          Believing is seeing and ignorance is bliss until it bites you in the ass!

                          Fervor is the weapon of the impotent. The harder the sell, the poorer the product.

                          Alas, my ignorance abounds; the more I've learned, the less I know that I know..........

                          Thou shalt seek and respect the opinions of operators, even unto the third helper, for theirs is a wisdom unknown to technicrats.

                          Wise men learn more from fools, than fools from wise men.

                          In my dotage I finally discovered that the secret to putting on pants both legs at a time is sitting down.


                          https://graywolfslair.com/

                          Comment


                            Originally posted by LostTribe View Post
                            what are recommendations for taking concentrates orally for cancer? The same as for the suppositories?
                            We've used the same dosages and gone through the same issues with building tolerance before administering 330 mg dosages three times a day.
                            An age is called Dark not because the light fails to shine, but because people refuse to see it.

                            Believing is seeing and ignorance is bliss until it bites you in the ass!

                            Fervor is the weapon of the impotent. The harder the sell, the poorer the product.

                            Alas, my ignorance abounds; the more I've learned, the less I know that I know..........

                            Thou shalt seek and respect the opinions of operators, even unto the third helper, for theirs is a wisdom unknown to technicrats.

                            Wise men learn more from fools, than fools from wise men.

                            In my dotage I finally discovered that the secret to putting on pants both legs at a time is sitting down.


                            https://graywolfslair.com/

                            Comment


                              Originally posted by Gray Wolf View Post
                              We've used the same dosages and gone through the same issues with building tolerance before administering 330 mg dosages three times a day.
                              I would have to agree. Three doses per day. Building up a tolerance can be difficult, but well worth the effort.

                              The most difficult thing in treating a couple of my patients was building up a tolerance. It took three months before we could start increasing the doses, but it went more smoothly from that point.

                              Comment


                                Dosing three times a day was problematic for one patient I'm currently working with.
                                Lack of tolerance was making it too hard for her to function/ up the dose.
                                Switching to four times a day helped her deal better and she got up to her target dose per day within a couple of weeks of switching to 4 daily doses.
                                Proud to be an indoor sativa masochist.

                                Still adrift in Hilbert space.

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